butyl hydroxybenzoate-6446 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the butyl hydroxybenzoate-6446 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACO2 aconitase 2, mitochondrial
ADCK4 aarF domain containing kinase 4
AIF1 allograft inflammatory factor 1
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ANXA2P3 annexin A2 pseudogene 3
APOC1 apolipoprotein C-I
AQP1 aquaporin 1 (Colton blood group)
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
BEGAIN brain-enriched guanylate kinase-associated
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
C18ORF25 chromosome 18 open reading frame 25
C19ORF66 chromosome 19 open reading frame 66
C21ORF2 chromosome 21 open reading frame 2
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CALD1 caldesmon 1
CD4 CD4 molecule
CD44 CD44 molecule (Indian blood group)
CDC25C cell division cycle 25C
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CEP135 centrosomal protein 135kDa
CFAP69 cilia and flagella associated protein 69
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
CLCA2 chloride channel accessory 2
CLDN1 claudin 1
CNN1 calponin 1, basic, smooth muscle
CREBBP CREB binding protein
DDIT3 DNA-damage-inducible transcript 3
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DSC1 desmocollin 1
EGR1 early growth response 1
EGR3 early growth response 3
EML2 echinoderm microtubule associated protein like 2
FBXL8 F-box and leucine-rich repeat protein 8
FOSL2 FOS-like antigen 2
FUS FUS RNA binding protein
GAP43 growth associated protein 43
GATA4 GATA binding protein 4
GEM GTP binding protein overexpressed in skeletal muscle
GFER growth factor, augmenter of liver regeneration
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GNG11 guanine nucleotide binding protein (G protein), gamma 11
HGD homogentisate 1,2-dioxygenase
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3
HYAL1 hyaluronoglucosaminidase 1
ICA1 islet cell autoantigen 1, 69kDa
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGHM immunoglobulin heavy constant mu
IKZF1 IKAROS family zinc finger 1 (Ikaros)
INHBE inhibin, beta E
JAK2 Janus kinase 2
LRP12 low density lipoprotein receptor-related protein 12
LRRC23 leucine rich repeat containing 23
MANBA mannosidase, beta A, lysosomal
MAX MYC associated factor X
MFAP3L microfibrillar-associated protein 3-like
MUC4 mucin 4, cell surface associated
MYL4 myosin, light chain 4, alkali; atrial, embryonic
MYOZ3 myozenin 3
NKX3-2 NK3 homeobox 2
NTN1 netrin 1
ORAI2 ORAI calcium release-activated calcium modulator 2
OSMR oncostatin M receptor
PCDHA6 protocadherin alpha 6
PGR progesterone receptor
PHYHIP phytanoyl-CoA 2-hydroxylase interacting protein
PIGR polymeric immunoglobulin receptor
PLCL2 phospholipase C-like 2
PLD1 phospholipase D1, phosphatidylcholine-specific
POM121 POM121 transmembrane nucleoporin
POPDC3 popeye domain containing 3
PPAP2B phosphatidic acid phosphatase type 2B
PPP4R4 protein phosphatase 4, regulatory subunit 4
PPP5C protein phosphatase 5, catalytic subunit
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PTGER3 prostaglandin E receptor 3 (subtype EP3)
RAD54B RAD54 homolog B (S. cerevisiae)
RFPL3 ret finger protein-like 3
RGS5 regulator of G-protein signaling 5
RIMBP2 RIMS binding protein 2
RNF19B ring finger protein 19B
SH3D21 SH3 domain containing 21
SIGLEC8 sialic acid binding Ig-like lectin 8
SIX1 SIX homeobox 1
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20
SPRR2B small proline-rich protein 2B
TBX10 T-box 10
TGM2 transglutaminase 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TPSG1 tryptase gamma 1
TRAF3IP3 TRAF3 interacting protein 3
TRIM36 tripartite motif containing 36
TTC38 tetratricopeptide repeat domain 38
TUBA3C tubulin, alpha 3c
WAS Wiskott-Aldrich syndrome

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
AFAP1 actin filament associated protein 1
AFF4 AF4/FMR2 family, member 4
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ANKRD28 ankyrin repeat domain 28
AR androgen receptor
ASPN asporin
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
C11ORF80 chromosome 11 open reading frame 80
C17ORF70 chromosome 17 open reading frame 70
CBX7 chromobox homolog 7
CCDC186 coiled-coil domain containing 186
CCP110 centriolar coiled coil protein 110kDa
CD3D CD3d molecule, delta (CD3-TCR complex)
CDK20 cyclin-dependent kinase 20
CHKB choline kinase beta
CHRM3 cholinergic receptor, muscarinic 3
CLCN6 chloride channel, voltage-sensitive 6
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DGKE diacylglycerol kinase, epsilon 64kDa
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DOK5 docking protein 5
DYSF dysferlin
EXOC5 exocyst complex component 5
FAM110B family with sequence similarity 110, member B
FBXO31 F-box protein 31
GLI3 GLI family zinc finger 3
GLTSCR1 glioma tumor suppressor candidate region gene 1
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GRPR gastrin-releasing peptide receptor
GRTP1 growth hormone regulated TBC protein 1
GTF2I general transcription factor IIi
HOXB2 homeobox B2
HP1BP3 heterochromatin protein 1, binding protein 3
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
IDI2-AS1 IDI2 antisense RNA 1
IL12RB1 interleukin 12 receptor, beta 1
INCENP inner centromere protein antigens 135/155kDa
IPO8 importin 8
KCTD20 potassium channel tetramerization domain containing 20
KDM8 lysine (K)-specific demethylase 8
KIAA1456 KIAA1456
LIME1 Lck interacting transmembrane adaptor 1
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LOXL3 lysyl oxidase-like 3
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LYPD1 LY6/PLAUR domain containing 1
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAST3 microtubule associated serine/threonine kinase 3
MBNL3 muscleblind-like splicing regulator 3
MED9 mediator complex subunit 9
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MT1HL1 metallothionein 1H-like 1
N4BP3 NEDD4 binding protein 3
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NPM3 nucleophosmin/nucleoplasmin 3
PCDHA9 protocadherin alpha 9
PGPEP1 pyroglutamyl-peptidase I
PLD3 phospholipase D family, member 3
PLEKHA6 pleckstrin homology domain containing, family A member 6
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PRDM14 PR domain containing 14
PROL1 proline rich, lacrimal 1
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RNF141 ring finger protein 141
SCAI suppressor of cancer cell invasion
SCGB2A2 secretoglobin, family 2A, member 2
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SFRP5 secreted frizzled-related protein 5
SLC12A8 solute carrier family 12, member 8
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)
STON1 stonin 1
SYNC syncoilin, intermediate filament protein
SYTL2 synaptotagmin-like 2
TCTN1 tectonic family member 1
TRABD TraB domain containing
TTC30A tetratricopeptide repeat domain 30A
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UBTD1 ubiquitin domain containing 1
UPK3B uroplakin 3B
USP27X ubiquitin specific peptidase 27, X-linked
WDR62 WD repeat domain 62
WDR76 WD repeat domain 76
ZC3H3 zinc finger CCCH-type containing 3
ZFP30 ZFP30 zinc finger protein
ZMAT5 zinc finger, matrin-type 5
ZNF324 zinc finger protein 324
ZNF33B zinc finger protein 33B
ZNF692 zinc finger protein 692