c-Ets-1 Gene Set

Dataset MotifMap Predicted Transcription Factor Targets
Category genomics
Type transcription factor
Description v-ets avian erythroblastosis virus E26 oncogene homolog 1|This gene encodes a member of the ETS family of transcription factors, which are defined by the presence of a conserved ETS DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T in target genes. These proteins function either as transcriptional activators or repressors of numerous genes, and are involved in stem cell development, cell senescence and death, and tumorigenesis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011] (NCBI Entrez Gene Database, 2113)
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Genes

74 target genes of the c-Ets-1 transcription factor predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.

Symbol Name
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1
ACADVL acyl-CoA dehydrogenase, very long chain
ADCY7 adenylate cyclase 7
AP2M1 adaptor-related protein complex 2, mu 1 subunit
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit
ARHGAP31 Rho GTPase activating protein 31
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
B3GNT5 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
BANK1 B-cell scaffold protein with ankyrin repeats 1
BAX BCL2-associated X protein
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
CANX calnexin
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast)
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1
CD40LG CD40 ligand
CLDN2 claudin 2
CNGA4 cyclic nucleotide gated channel alpha 4
CTTNBP2NL CTTNBP2 N-terminal like
DGUOK deoxyguanosine kinase
DOCK5 dedicator of cytokinesis 5
DTX4 deltex 4, E3 ubiquitin ligase
DUSP6 dual specificity phosphatase 6
DUSP7 dual specificity phosphatase 7
E2F3 E2F transcription factor 3
E2F5 E2F transcription factor 5, p130-binding
EGFLAM EGF-like, fibronectin type III and laminin G domains
EHBP1L1 EH domain binding protein 1-like 1
FAM134A family with sequence similarity 134, member A
FAM65A family with sequence similarity 65, member A
FURIN furin (paired basic amino acid cleaving enzyme)
GGNBP2 gametogenetin binding protein 2
GMPR2 guanosine monophosphate reductase 2
HGFAC HGF activator
HMGA1 high mobility group AT-hook 1
HNRNPUL2-BSCL2 HNRNPUL2-BSCL2 readthrough (NMD candidate)
HOXC4 homeobox C4
KIAA1522 KIAA1522
KIF1C kinesin family member 1C
LCK LCK proto-oncogene, Src family tyrosine kinase
LST1 leukocyte specific transcript 1
LYN LYN proto-oncogene, Src family tyrosine kinase
MADD MAP-kinase activating death domain
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MIR1284 microRNA 1284
MIR208A microRNA 208a
MIR365A microRNA 365a
MIR4505 microRNA 4505
MIR494 microRNA 494
MPG N-methylpurine-DNA glycosylase
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)
NR5A2 nuclear receptor subfamily 5, group A, member 2
PEAR1 platelet endothelial aggregation receptor 1
PER2 period circadian clock 2
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4
RBMS2 RNA binding motif, single stranded interacting protein 2
RIIAD1 regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1
RIN3 Ras and Rab interactor 3
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
SEC24C SEC24 family member C
SH3BP2 SH3-domain binding protein 2
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SPNS3 spinster homolog 3 (Drosophila)
TDRD7 tudor domain containing 7
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNNI2 troponin I type 2 (skeletal, fast)
TPP2 tripeptidyl peptidase II
TTN titin
TWIST1 twist family bHLH transcription factor 1
USP53 ubiquitin specific peptidase 53
VAC14 Vac14 homolog (S. cerevisiae)
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WDR43 WD repeat domain 43
ZNF35 zinc finger protein 35