| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | c-Kit-IN-1 perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the c-Kit-IN-1_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIO | trio Rho guanine nucleotide exchange factor | 0.230382 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.18649 |
| DST | dystonin | 0.129595 |
| SLC39A11 | solute carrier family 39, member 11 | 0.120582 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.114217 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.104462 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0959399 |
| FRMD5 | FERM domain containing 5 | 0.0901697 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0896061 |
| TENM3 | teneurin transmembrane protein 3 | 0.0877264 |
| HDAC9 | histone deacetylase 9 | 0.0813489 |
| AUTS2 | autism susceptibility candidate 2 | 0.0754022 |
| RUNX1 | runt-related transcription factor 1 | 0.0691861 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0670112 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0665359 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0643084 |
| MSI2 | musashi RNA-binding protein 2 | 0.0622593 |
| NDRG1 | N-myc downstream regulated 1 | 0.0612039 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.060234 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0592108 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0587127 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0583428 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.057301 |
| CD109 | CD109 molecule | 0.0572541 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0565083 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0563424 |
| NAV2 | neuron navigator 2 | 0.0554879 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0551265 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0540425 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0523113 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0500752 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0499226 |
| ANK2 | ankyrin 2, neuronal | 0.0497587 |
| CANX | calnexin | 0.047179 |
| OR51B5 | olfactory receptor, family 51, subfamily B, member 5 | 0.0466349 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0463786 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0455233 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0454644 |
| FLNB | filamin B, beta | 0.0450706 |
| APP | amyloid beta (A4) precursor protein | 0.0450083 |
| COPA | coatomer protein complex, subunit alpha | 0.0441706 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0438933 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | 0.043877 |
| LDHA | lactate dehydrogenase A | 0.0436083 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0434603 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0413215 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0411075 |
| HELZ | helicase with zinc finger | 0.0410502 |
| FLNA | filamin A, alpha | 0.040708 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0402461 |
| COL5A1 | collagen, type V, alpha 1 | 0.039722 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | 0.0389354 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0388159 |
| ARFGEF3 | ARFGEF family member 3 | 0.0378668 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0377354 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0371658 |
| PRELID2 | PRELI domain containing 2 | 0.0370887 |
| TPM3 | tropomyosin 3 | 0.0370632 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0368219 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0366861 |
| EGFR | epidermal growth factor receptor | 0.0365933 |
| MSN | moesin | 0.0362523 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0359417 |
| FSTL1 | follistatin-like 1 | 0.0358928 |
| FNIP1 | folliculin interacting protein 1 | 0.0357644 |
| FAM219A | family with sequence similarity 219, member A | 0.0356777 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0356771 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0354735 |
| MAP1B | microtubule-associated protein 1B | 0.0351765 |
| USP34 | ubiquitin specific peptidase 34 | 0.0351563 |
| GOLGA4 | golgin A4 | 0.0351394 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0348197 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0347588 |
| TUFT1 | tuftelin 1 | 0.0344092 |
| RND3 | Rho family GTPase 3 | 0.0342801 |
| ZNF207 | zinc finger protein 207 | 0.0342393 |
| MYOF | myoferlin | 0.0341124 |
| ATP13A3 | ATPase type 13A3 | 0.0339173 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.0335974 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0335838 |
| TAOK1 | TAO kinase 1 | 0.0334075 |
| ANO6 | anoctamin 6 | 0.0327454 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0327353 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | 0.0325345 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.0324738 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0317578 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0314709 |
| RTN4 | reticulon 4 | 0.0313594 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0312515 |
| NBAS | neuroblastoma amplified sequence | 0.0312293 |
| GPC6 | glypican 6 | 0.0309878 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0307256 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.03058 |
| FMNL2 | formin-like 2 | 0.0305269 |
| SFTPA2 | surfactant protein A2 | 0.0304943 |
| DENND1A | DENN/MADD domain containing 1A | 0.030373 |
| PLEC | plectin | 0.0302643 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0300006 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0297666 |
| NUP58 | nucleoporin 58 | 0.0294303 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.14783 |
| VIM | vimentin | -0.145877 |
| MT2A | metallothionein 2A | -0.126391 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.114918 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0957885 |
| LOX | lysyl oxidase | -0.079019 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0783023 |
| COL1A2 | collagen, type I, alpha 2 | -0.0647311 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0629455 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0609973 |
| HLA-B | major histocompatibility complex, class I, B | -0.0608363 |
| COL3A1 | collagen, type III, alpha 1 | -0.0597661 |
| S100A10 | S100 calcium binding protein A10 | -0.0580894 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0568954 |
| SUCNR1 | succinate receptor 1 | -0.0504227 |
| FBN1 | fibrillin 1 | -0.0471997 |
| PRSS23 | protease, serine, 23 | -0.0468353 |
| MX2 | MX dynamin-like GTPase 2 | -0.0467649 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0452209 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0450634 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0447654 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0424683 |
| B2M | beta-2-microglobulin | -0.041023 |
| S100A6 | S100 calcium binding protein A6 | -0.0404129 |
| THBS2 | thrombospondin 2 | -0.0395986 |
| HLA-C | major histocompatibility complex, class I, C | -0.0372543 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0356151 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0353649 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0352173 |
| PTMA | prothymosin, alpha | -0.0347985 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0337063 |
| CD44 | CD44 molecule (Indian blood group) | -0.0333017 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0323365 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0322251 |
| CAVIN1 | caveolae associated protein 1 | -0.0319304 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0287902 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.028728 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0284843 |
| RPL12 | ribosomal protein L12 | -0.0278815 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0277042 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0276577 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0272561 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0271798 |
| RIGI | RNA sensor RIG-I | -0.0271319 |
| COL5A2 | collagen, type V, alpha 2 | -0.0270249 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0263917 |
| RPS23 | ribosomal protein S23 | -0.026185 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0260493 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0251089 |
| S100A4 | S100 calcium binding protein A4 | -0.0250296 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0245658 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0244256 |
| FTL | ferritin, light polypeptide | -0.0242266 |
| FN1 | fibronectin 1 | -0.0240562 |
| MYADM | myeloid-associated differentiation marker | -0.023908 |
| RPL35A | ribosomal protein L35a | -0.0235162 |
| RPLP1 | ribosomal protein, large, P1 | -0.0232731 |
| TMSB4X | thymosin beta 4, X-linked | -0.0232219 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0231658 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0230736 |
| RPS8 | ribosomal protein S8 | -0.0229832 |
| RPL34 | ribosomal protein L34 | -0.0228671 |
| NAV1 | neuron navigator 1 | -0.0227986 |
| CD99 | CD99 molecule | -0.0219266 |
| RPL37A | ribosomal protein L37a | -0.0218404 |
| NPR2 | natriuretic peptide receptor 2 | -0.0215858 |
| RPS6 | ribosomal protein S6 | -0.0215495 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0215392 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0212772 |
| RPL28 | ribosomal protein L28 | -0.0212353 |
| SP100 | SP100 nuclear antigen | -0.0211532 |
| RRBP1 | ribosome binding protein 1 | -0.0208203 |
| FRMD4A | FERM domain containing 4A | -0.0207095 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0205781 |
| RPLP2 | ribosomal protein, large, P2 | -0.0205753 |
| SEC61G | Sec61 gamma subunit | -0.020482 |
| RPL26 | ribosomal protein L26 | -0.020331 |
| RPS24 | ribosomal protein S24 | -0.0201731 |
| CD63 | CD63 molecule | -0.0201359 |
| RPL36 | ribosomal protein L36 | -0.0196739 |
| EDF1 | endothelial differentiation-related factor 1 | -0.0195242 |
| RPS13 | ribosomal protein S13 | -0.019519 |
| STC1 | stanniocalcin 1 | -0.0191147 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0190223 |
| HLA-E | major histocompatibility complex, class I, E | -0.018862 |
| SAMD9L | sterile alpha motif domain containing 9-like | -0.0187898 |
| RPL38 | ribosomal protein L38 | -0.0187111 |
| RPS27A | ribosomal protein S27a | -0.0185941 |
| CBX3 | chromobox homolog 3 | -0.0184233 |
| RPL23 | ribosomal protein L23 | -0.0184136 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0181738 |
| S100A11 | S100 calcium binding protein A11 | -0.0181467 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0181079 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0180628 |
| PLAT | plasminogen activator, tissue | -0.0176057 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0173467 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0172656 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0170861 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0168618 |
| ACTG1 | actin gamma 1 | -0.0167144 |
