| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | c-Kit-IN-1 perturbation in A549 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the c-Kit-IN-1_A549 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC35F3 | solute carrier family 35, member F3 | 0.109506 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0982779 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0928811 |
| EFNA5 | ephrin-A5 | 0.0922038 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0890574 |
| PLEC | plectin | 0.0889383 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0887745 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0880558 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0808547 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0808127 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0785139 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0750337 |
| EGFR | epidermal growth factor receptor | 0.0706732 |
| AUTS2 | autism susceptibility candidate 2 | 0.0691127 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0678316 |
| AHNAK | AHNAK nucleoprotein | 0.0622879 |
| ACTN4 | actinin, alpha 4 | 0.0620686 |
| CMIP | c-Maf inducing protein | 0.0620271 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0613772 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0612089 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0607261 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0604587 |
| EHBP1 | EH domain binding protein 1 | 0.0583626 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0580144 |
| RNF213 | ring finger protein 213 | 0.0574832 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0572621 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0570563 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0569677 |
| FLNA | filamin A, alpha | 0.056 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.054719 |
| PTK2 | protein tyrosine kinase 2 | 0.0540483 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0531088 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0529052 |
| FAT1 | FAT atypical cadherin 1 | 0.0524899 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0522521 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0516261 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0506219 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.050475 |
| ASPH | aspartate beta-hydroxylase | 0.0486226 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0479413 |
| FNIP1 | folliculin interacting protein 1 | 0.0459556 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0451943 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0450705 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0448217 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0438279 |
| VCL | vinculin | 0.0436849 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0427651 |
| DST | dystonin | 0.0422326 |
| PRKCA | protein kinase C, alpha | 0.042087 |
| HMGA2 | high mobility group AT-hook 2 | 0.0408374 |
| INTS6 | integrator complex subunit 6 | 0.0407617 |
| ANXA2 | annexin A2 | 0.0402202 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0401381 |
| WWOX | WW domain containing oxidoreductase | 0.0398599 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0391309 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0388697 |
| MSI2 | musashi RNA-binding protein 2 | 0.0376643 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | 0.0374843 |
| MYO10 | myosin X | 0.0370511 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0370504 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0370161 |
| TNS3 | tensin 3 | 0.0369637 |
| NRG1 | neuregulin 1 | 0.0369365 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0367862 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0366546 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0361781 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0359545 |
| TCF12 | transcription factor 12 | 0.035915 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0358914 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0356093 |
| RAD51B | RAD51 paralog B | 0.0350508 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0349105 |
| SQSTM1 | sequestosome 1 | 0.0348599 |
| MYO1E | myosin IE | 0.0348257 |
| FN1 | fibronectin 1 | 0.0347139 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0345297 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.034504 |
| KIRREL3 | kin of IRRE like 3 (Drosophila) | 0.0341311 |
| NF1 | neurofibromin 1 | 0.0338941 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0335687 |
| PALLD | palladin, cytoskeletal associated protein | 0.0333963 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0331625 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0329419 |
| DENND1A | DENN/MADD domain containing 1A | 0.0328715 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0324502 |
| GPC6 | glypican 6 | 0.0321947 |
| SP100 | SP100 nuclear antigen | 0.0321351 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0316294 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.0316236 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0312378 |
| RHCG | Rh family, C glycoprotein | 0.0312004 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0311626 |
| EZR | ezrin | 0.0307041 |
| BICC1 | BicC family RNA binding protein 1 | 0.0305471 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0301712 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0300773 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0299574 |
| MED13 | mediator complex subunit 13 | 0.0297728 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0295398 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0292085 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.160156 |
| MT2A | metallothionein 2A | -0.156414 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.152307 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.122456 |
| FTL | ferritin, light polypeptide | -0.0991622 |
| TMSB10 | thymosin beta 10 | -0.0927005 |
| MT1X | metallothionein 1X | -0.072429 |
| STC1 | stanniocalcin 1 | -0.0712761 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0704343 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0603677 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0598683 |
| KCTD9 | potassium channel tetramerization domain containing 9 | -0.0578876 |
| RPLP1 | ribosomal protein, large, P1 | -0.0571563 |
| RPS6 | ribosomal protein S6 | -0.0545134 |
| ACTG1 | actin gamma 1 | -0.0538778 |
| RPS19 | ribosomal protein S19 | -0.0522176 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0487664 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0451895 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0450028 |
| UBC | ubiquitin C | -0.0431895 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0414351 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.0412097 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0409294 |
| RPS2 | ribosomal protein S2 | -0.0394426 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | -0.0383316 |
| USP3 | ubiquitin specific peptidase 3 | -0.0375534 |
| VIM | vimentin | -0.0372299 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0372248 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.037003 |
| S100A6 | S100 calcium binding protein A6 | -0.0367353 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0367004 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0362462 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0356569 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0352913 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0349086 |
| AGFG1 | ArfGAP with FG repeats 1 | -0.0340814 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0335672 |
| TXNRD1 | thioredoxin reductase 1 | -0.0334448 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0332506 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0327838 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0321187 |
| PFN1 | profilin 1 | -0.0315741 |
| RPL28 | ribosomal protein L28 | -0.0303977 |
| PTMA | prothymosin, alpha | -0.0297676 |
| AXL | AXL receptor tyrosine kinase | -0.0286652 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0286305 |
| KRT81 | keratin 81, type II | -0.0275901 |
| RIN2 | Ras and Rab interactor 2 | -0.0274893 |
| NDRG1 | N-myc downstream regulated 1 | -0.0274602 |
| RPS16 | ribosomal protein S16 | -0.0273321 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0272496 |
| RPL26 | ribosomal protein L26 | -0.026742 |
| RPL7 | ribosomal protein L7 | -0.0267093 |
| CDCA2 | cell division cycle associated 2 | -0.026661 |
| YBX3 | Y box binding protein 3 | -0.0265368 |
| ANGPTL4 | angiopoietin-like 4 | -0.0261825 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0259441 |
| RPS13 | ribosomal protein S13 | -0.0254712 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0247015 |
| RPS27A | ribosomal protein S27a | -0.024204 |
| RPL18 | ribosomal protein L18 | -0.0241642 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0239611 |
| RPS23 | ribosomal protein S23 | -0.023259 |
| RPS8 | ribosomal protein S8 | -0.0232193 |
| HELZ | helicase with zinc finger | -0.0230623 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0227597 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0221786 |
| GPRIN3 | GPRIN family member 3 | -0.0220375 |
| OGA | O-GlcNAcase | -0.0220368 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0218312 |
| RPL12 | ribosomal protein L12 | -0.0218163 |
| RPL32 | ribosomal protein L32 | -0.0214685 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0213575 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0212127 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.0211865 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0210891 |
| RPS3 | ribosomal protein S3 | -0.0209761 |
| RPS5 | ribosomal protein S5 | -0.0208787 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0208695 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0204011 |
| WASF2 | WAS protein family, member 2 | -0.0201849 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0200319 |
| RPS29 | ribosomal protein S29 | -0.0198028 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0197615 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0195921 |
| SRGN | serglycin | -0.0192221 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.01893 |
| RPS21 | ribosomal protein S21 | -0.0188123 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0187626 |
| RNF24 | ring finger protein 24 | -0.0187352 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0185156 |
| S100A10 | S100 calcium binding protein A10 | -0.0185133 |
| KLF6 | Kruppel-like factor 6 | -0.018452 |
| RPL38 | ribosomal protein L38 | -0.0184296 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0183857 |
| CEP95 | centrosomal protein 95kDa | -0.0182871 |
| RPL8 | ribosomal protein L8 | -0.0182733 |
| SPAG9 | sperm associated antigen 9 | -0.0180038 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0179942 |
| RPLP0 | ribosomal protein, large, P0 | -0.0177964 |
