| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | c-Kit-IN-1 perturbation in AN3 CA cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the c-Kit-IN-1_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PEG10 | paternally expressed 10 | 0.149566 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.116178 |
| HMGA2 | high mobility group AT-hook 2 | 0.107147 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0988461 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0986894 |
| MSRB3 | methionine sulfoxide reductase B3 | 0.0916672 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0872793 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.084025 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0783154 |
| ATRNL1 | attractin-like 1 | 0.0755346 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0689948 |
| VEGFA | vascular endothelial growth factor A | 0.0681637 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0651107 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0599525 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.059784 |
| SIK3 | SIK family kinase 3 | 0.0594673 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0591251 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0587336 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0554217 |
| GPC6 | glypican 6 | 0.0542157 |
| PDGFC | platelet derived growth factor C | 0.0532652 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0525706 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0515972 |
| TULP4 | tubby like protein 4 | 0.0506488 |
| APP | amyloid beta (A4) precursor protein | 0.0505774 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.050014 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0495242 |
| CTBP2 | C-terminal binding protein 2 | 0.0491294 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0490498 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0481913 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | 0.0481441 |
| JMJD1C | jumonji domain containing 1C | 0.0475043 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0465618 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0462204 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0461514 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0460905 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0460579 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0456775 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0455766 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0451257 |
| NBAS | neuroblastoma amplified sequence | 0.0445409 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.0443612 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0441851 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0438776 |
| PCDH7 | protocadherin 7 | 0.0432918 |
| ZNF638 | zinc finger protein 638 | 0.0432101 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0428917 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0428143 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0423194 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0423078 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0416742 |
| NPTN | neuroplastin | 0.0413228 |
| MED13L | mediator complex subunit 13-like | 0.0409333 |
| PTK2 | protein tyrosine kinase 2 | 0.0409125 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0407609 |
| WWC2 | WW and C2 domain containing 2 | 0.040747 |
| SHROOM3 | shroom family member 3 | 0.040552 |
| SMYD3 | SET and MYND domain containing 3 | 0.039889 |
| IGF2R | insulin-like growth factor 2 receptor | 0.039457 |
| NUP58 | nucleoporin 58 | 0.0388567 |
| ZNF608 | zinc finger protein 608 | 0.0387961 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0385352 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0381866 |
| MATR3 | matrin 3 | 0.0381509 |
| GSK3B | glycogen synthase kinase 3 beta | 0.037932 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0373169 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.0372737 |
| TAOK1 | TAO kinase 1 | 0.0372246 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.037185 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.037064 |
| UTRN | utrophin | 0.0369222 |
| TRAF3 | TNF receptor-associated factor 3 | 0.036785 |
| SRPK2 | SRSF protein kinase 2 | 0.0367301 |
| CLIC4 | chloride intracellular channel 4 | 0.0364667 |
| GSE1 | Gse1 coiled-coil protein | 0.036337 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0361652 |
| IPO7 | importin 7 | 0.0361345 |
| NCKAP1 | NCK-associated protein 1 | 0.0359194 |
| ADIPOR2 | adiponectin receptor 2 | 0.0355463 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0354539 |
| MKI67 | marker of proliferation Ki-67 | 0.0353246 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0353111 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0352358 |
| PKM | pyruvate kinase, muscle | 0.0351991 |
| FMNL2 | formin-like 2 | 0.03494 |
| PDS5B | PDS5 cohesin associated factor B | 0.0349382 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0348155 |
| LDHA | lactate dehydrogenase A | 0.0346944 |
| IVNS1ABP | influenza virus NS1A binding protein | 0.0346166 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0345957 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0345194 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0344949 |
| NDRG1 | N-myc downstream regulated 1 | 0.0344727 |
| ASPH | aspartate beta-hydroxylase | 0.0344593 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0342607 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0341195 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0340541 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0339792 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0338315 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0337508 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MEST | mesoderm specific transcript | -0.154564 |
| CENPF | centromere protein F, 350/400kDa | -0.0811885 |
| MEOX2 | mesenchyme homeobox 2 | -0.0805668 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0734151 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0548095 |
| RPLP0 | ribosomal protein, large, P0 | -0.0500681 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0470236 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0463882 |
| TPK1 | thiamin pyrophosphokinase 1 | -0.0456584 |
| COL1A2 | collagen, type I, alpha 2 | -0.0441767 |
| BTBD3 | BTB (POZ) domain containing 3 | -0.0437705 |
| MGP | matrix Gla protein | -0.0425844 |
| RPS6 | ribosomal protein S6 | -0.0393484 |
| TUBB | tubulin, beta class I | -0.0386365 |
| RPL13A | ribosomal protein L13a | -0.0369666 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0363828 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0350402 |
| SQSTM1 | sequestosome 1 | -0.0346879 |
| KLHL24 | kelch-like family member 24 | -0.0341984 |
| SERINC1 | serine incorporator 1 | -0.0338405 |
| KLHDC10 | kelch domain containing 10 | -0.0335226 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | -0.0326209 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0307148 |
| NCAPG | non-SMC condensin I complex, subunit G | -0.0302433 |
| WBP11 | WW domain binding protein 11 | -0.0299665 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | -0.0296289 |
| RPS27A | ribosomal protein S27a | -0.0292648 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.029186 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0279589 |
| KANTR | KDM5C adjacent non-coding transcript | -0.0279511 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.027175 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0270308 |
| IER3 | immediate early response 3 | -0.0268061 |
| RPS8 | ribosomal protein S8 | -0.0267354 |
| DDX50 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 | -0.0264152 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0263847 |
| HOXC10 | homeobox C10 | -0.0261959 |
| AKAP10 | A kinase (PRKA) anchor protein 10 | -0.0252465 |
| NFIA | nuclear factor I/A | -0.024262 |
| RSF1 | remodeling and spacing factor 1 | -0.0239826 |
| CIRSR | corepressor of RBPJ and splicing regulator | -0.0237422 |
| KIF18A | kinesin family member 18A | -0.0236565 |
| HDAC8 | histone deacetylase 8 | -0.0236186 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | -0.0234767 |
| CREBRF | CREB3 regulatory factor | -0.0234019 |
| SHOC2 | soc-2 suppressor of clear homolog (C. elegans) | -0.0233445 |
| UBB | ubiquitin B | -0.0232434 |
| PSMB2 | proteasome (prosome, macropain) subunit, beta type, 2 | -0.0229287 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0227126 |
| RPS3 | ribosomal protein S3 | -0.0226544 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | -0.0221273 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 | -0.0215442 |
| ATXN10 | ataxin 10 | -0.0214291 |
| AHI1 | Abelson helper integration site 1 | -0.0213854 |
| SEMA6A | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A | -0.0213381 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0210902 |
| TPR | translocated promoter region, nuclear basket protein | -0.0207009 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0203095 |
| SHISA3 | shisa family member 3 | -0.0202345 |
| PPIP5K2 | diphosphoinositol pentakisphosphate kinase 2 | -0.0201468 |
| HBP1 | HMG-box transcription factor 1 | -0.0200074 |
| STAG2 | stromal antigen 2 | -0.0197 |
| LMO4 | LIM domain only 4 | -0.0196253 |
| YTHDF2 | YTH N(6)-methyladenosine RNA binding protein 2 | -0.0195773 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.019437 |
| B2M | beta-2-microglobulin | -0.0192531 |
| KIF11 | kinesin family member 11 | -0.0190337 |
| CDC37 | cell division cycle 37 | -0.0189944 |
| ZNF395 | zinc finger protein 395 | -0.0187221 |
| TTK | TTK protein kinase | -0.0186777 |
| STIL | SCL/TAL1 interrupting locus | -0.0186586 |
| ITM2B | integral membrane protein 2B | -0.0185076 |
| ATP6V0E1 | ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 | -0.0184457 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0182828 |
| SCAMP1 | secretory carrier membrane protein 1 | -0.0181736 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0181492 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0181163 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0181109 |
| DSTN | destrin (actin depolymerizing factor) | -0.0180021 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0176551 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0175945 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | -0.0174903 |
| IFT88 | intraflagellar transport 88 | -0.017483 |
| NEK7 | NIMA-related kinase 7 | -0.0174738 |
| USP40 | ubiquitin specific peptidase 40 | -0.0174594 |
| SARAF | store-operated calcium entry-associated regulatory factor | -0.0173314 |
| RPS15 | ribosomal protein S15 | -0.0172738 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0171878 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0170911 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0170566 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0170314 |
| CHD6 | chromodomain helicase DNA binding protein 6 | -0.0169535 |
| RPS10 | ribosomal protein S10 | -0.016949 |
| UBC | ubiquitin C | -0.0168595 |
| OSBPL9 | oxysterol binding protein-like 9 | -0.0168554 |
| EPC1 | enhancer of polycomb homolog 1 (Drosophila) | -0.0167899 |
| CDCA2 | cell division cycle associated 2 | -0.0167614 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0166915 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0165742 |
| EGFR | epidermal growth factor receptor | -0.0165519 |
