| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | c-Kit-IN-1 perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the c-Kit-IN-1_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FMN1 | formin 1 | 0.161829 |
| VCL | vinculin | 0.147503 |
| TRIB2 | tribbles pseudokinase 2 | 0.115738 |
| DST | dystonin | 0.1137 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.106979 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.100264 |
| LSAMP | limbic system-associated membrane protein | 0.0987781 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | 0.0984496 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0947181 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.0905192 |
| FRMD5 | FERM domain containing 5 | 0.0837942 |
| DKK2 | dickkopf WNT signaling pathway inhibitor 2 | 0.0816286 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0774309 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0740281 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0712215 |
| DACH2 | dachshund family transcription factor 2 | 0.0702196 |
| PRKCA | protein kinase C, alpha | 0.0700285 |
| ACTG1 | actin gamma 1 | 0.0699792 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0690944 |
| MSI2 | musashi RNA-binding protein 2 | 0.0591768 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0585057 |
| SEPTIN9 | septin 9 | 0.0577014 |
| KLHL13 | kelch-like family member 13 | 0.0517799 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0492382 |
| NCAM2 | neural cell adhesion molecule 2 | 0.0488618 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0477372 |
| ENAH | enabled homolog (Drosophila) | 0.046754 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0459648 |
| PCDH9 | protocadherin 9 | 0.0457264 |
| TCF12 | transcription factor 12 | 0.0442029 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0432845 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0421573 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0417219 |
| ZNRF3 | zinc and ring finger 3 | 0.0410192 |
| ZNF804A | zinc finger protein 804A | 0.0404807 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0403783 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0400871 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0399369 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0394753 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0391135 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0385567 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) | 0.0382321 |
| VCAN | versican | 0.0374852 |
| UNC5C | unc-5 homolog C (C. elegans) | 0.0370902 |
| INTS6 | integrator complex subunit 6 | 0.0369275 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0366953 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0359868 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0352601 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0348748 |
| GREM2 | gremlin 2, DAN family BMP antagonist | 0.0346467 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0346241 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0342936 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0341808 |
| DGKH | diacylglycerol kinase, eta | 0.0339401 |
| DNM3 | dynamin 3 | 0.0339083 |
| TMEM108 | transmembrane protein 108 | 0.0335333 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0335078 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0335028 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0331761 |
| MAP1B | microtubule-associated protein 1B | 0.0330172 |
| TPM1 | tropomyosin 1 (alpha) | 0.0328833 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0323952 |
| TULP4 | tubby like protein 4 | 0.0321984 |
| SACS | sacsin molecular chaperone | 0.0321824 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.031851 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0315234 |
| PCDH15 | protocadherin-related 15 | 0.0313708 |
| ACTN1 | actinin, alpha 1 | 0.0309264 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0308415 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0300338 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0298724 |
| MCL1 | myeloid cell leukemia 1 | 0.0296739 |
| ITGA1 | integrin, alpha 1 | 0.02945 |
| MYO1E | myosin IE | 0.0293824 |
| FERMT2 | fermitin family member 2 | 0.0293586 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0293264 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0290326 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0288677 |
| MALT1 | MALT1 paracaspase | 0.0287735 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0268467 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | 0.0268212 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0265085 |
| FLNA | filamin A, alpha | 0.0265078 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0265035 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0263388 |
| PNN | pinin, desmosome associated protein | 0.0261411 |
| TENM4 | teneurin transmembrane protein 4 | 0.0258323 |
| VEGFA | vascular endothelial growth factor A | 0.0257815 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0257356 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0256371 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0253511 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.025237 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0250387 |
| MRTFA | myocardin related transcription factor A | 0.0245874 |
| TPM4 | tropomyosin 4 | 0.0244414 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | 0.0244011 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0243405 |
| STK38L | serine/threonine kinase 38 like | 0.024159 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0239868 |
| LIMA1 | LIM domain and actin binding 1 | 0.0237483 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.257486 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.212405 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.131624 |
| FAM13A | family with sequence similarity 13, member A | -0.0836373 |
| VIM | vimentin | -0.0768402 |
| PLAT | plasminogen activator, tissue | -0.0763114 |
| PTMA | prothymosin, alpha | -0.0750739 |
| HELZ | helicase with zinc finger | -0.0628431 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0624745 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0584708 |
| FNBP1 | formin binding protein 1 | -0.0539999 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0525125 |
| ZNF292 | zinc finger protein 292 | -0.0522722 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0516465 |
| OGA | O-GlcNAcase | -0.0505218 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0493829 |
| NDRG1 | N-myc downstream regulated 1 | -0.0488365 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0474319 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0433233 |
| LPIN1 | lipin 1 | -0.043174 |
| NEK7 | NIMA-related kinase 7 | -0.0426792 |
| RPLP1 | ribosomal protein, large, P1 | -0.0425272 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0418033 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0397714 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0390539 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0388215 |
| RPL38 | ribosomal protein L38 | -0.0380167 |
| B2M | beta-2-microglobulin | -0.0376006 |
| RPS6 | ribosomal protein S6 | -0.0367019 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0365139 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.036353 |
| SYT1 | synaptotagmin I | -0.0360307 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0357429 |
| HAND2 | heart and neural crest derivatives expressed 2 | -0.035392 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0350933 |
| COL1A1 | collagen, type I, alpha 1 | -0.0350029 |
| SBF2 | SET binding factor 2 | -0.0347994 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0347873 |
| CDK19 | cyclin-dependent kinase 19 | -0.0347276 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0347228 |
| RPL34 | ribosomal protein L34 | -0.0340676 |
| WDR45B | WD repeat domain 45B | -0.0336346 |
| HMGB2 | high mobility group box 2 | -0.0332733 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0332508 |
| KLHL24 | kelch-like family member 24 | -0.0331411 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0328575 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0322107 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0319282 |
| TMSB10 | thymosin beta 10 | -0.0312059 |
| C1ORF21 | chromosome 1 open reading frame 21 | -0.0310936 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0310847 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0310438 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0306119 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0299768 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0299479 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0298949 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0291371 |
| S100A9 | S100 calcium binding protein A9 | -0.0283949 |
| NBR1 | neighbor of BRCA1 gene 1 | -0.0283345 |
| MBTD1 | mbt domain containing 1 | -0.0280926 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | -0.0276661 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0275323 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | -0.0273542 |
| RPS19 | ribosomal protein S19 | -0.0270505 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0265224 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.0260145 |
| H3-3B | H3.3 histone B | -0.0252454 |
| FTL | ferritin, light polypeptide | -0.0252312 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0252192 |
| PHF21A | PHD finger protein 21A | -0.0251738 |
| RPL35A | ribosomal protein L35a | -0.0251178 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.0250208 |
| MEIS2 | Meis homeobox 2 | -0.0249371 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0246046 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0245393 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0245257 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0244821 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0243816 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.0242091 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.0239333 |
| SRP54 | signal recognition particle 54kDa | -0.0238376 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0237946 |
| HIP1 | huntingtin interacting protein 1 | -0.0234884 |
| CREBRF | CREB3 regulatory factor | -0.0234129 |
| PRTG | protogenin | -0.0234108 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0234033 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0233786 |
| HDAC5 | histone deacetylase 5 | -0.0231263 |
| PCM1 | pericentriolar material 1 | -0.0229777 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0227424 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | -0.0227339 |
| PARD3 | par-3 family cell polarity regulator | -0.022686 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0225428 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | -0.022523 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0224282 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.022245 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0222337 |
| PHF3 | PHD finger protein 3 | -0.0221619 |
| COL3A1 | collagen, type III, alpha 1 | -0.0221402 |
| PHIP | pleckstrin homology domain interacting protein | -0.0221233 |
