| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | c-Kit-IN-1 perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the c-Kit-IN-1_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | 0.113173 |
| EXT1 | exostosin glycosyltransferase 1 | 0.103538 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0621807 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0600254 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0502664 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0502588 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0501593 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0499917 |
| PDZD8 | PDZ domain containing 8 | 0.0482779 |
| SQSTM1 | sequestosome 1 | 0.0482487 |
| FRMD5 | FERM domain containing 5 | 0.0449207 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0401937 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0394304 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0371785 |
| NUP58 | nucleoporin 58 | 0.0364671 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0357674 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0317525 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0306281 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0303421 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0291536 |
| LAMB3 | laminin, beta 3 | 0.0288494 |
| NCKAP1 | NCK-associated protein 1 | 0.0285476 |
| RASEF | RAS and EF-hand domain containing | 0.0281116 |
| PCDHB16 | protocadherin beta 16 | 0.0280491 |
| LDHA | lactate dehydrogenase A | 0.0276199 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0275464 |
| TNPO1 | transportin 1 | 0.027302 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0262986 |
| PLEC | plectin | 0.0249474 |
| ASPH | aspartate beta-hydroxylase | 0.0249251 |
| SIK3 | SIK family kinase 3 | 0.02486 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0241727 |
| SPAG9 | sperm associated antigen 9 | 0.0239618 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0235274 |
| FOXO3 | forkhead box O3 | 0.0232726 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0231122 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0227173 |
| MKI67 | marker of proliferation Ki-67 | 0.0224864 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0221809 |
| TOP1 | topoisomerase (DNA) I | 0.0219197 |
| TFRC | transferrin receptor | 0.0217116 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0216127 |
| IPO7 | importin 7 | 0.0215361 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.020442 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0201184 |
| SMAD3 | SMAD family member 3 | 0.0200352 |
| OLA1 | Obg-like ATPase 1 | 0.019932 |
| EMP1 | epithelial membrane protein 1 | 0.0198083 |
| CRY1 | cryptochrome circadian clock 1 | 0.0197473 |
| AXIN2 | axin 2 | 0.0196997 |
| RND3 | Rho family GTPase 3 | 0.0196684 |
| ANXA1 | annexin A1 | 0.0195726 |
| ATP13A3 | ATPase type 13A3 | 0.0194882 |
| SLTM | SAFB-like, transcription modulator | 0.0193066 |
| NTN4 | netrin 4 | 0.0192983 |
| MYO5B | myosin VB | 0.0188575 |
| GCLM | glutamate-cysteine ligase, modifier subunit | 0.0187955 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0186151 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0183113 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.018211 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | 0.018132 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0181133 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.017329 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0173154 |
| ARRDC3 | arrestin domain containing 3 | 0.0172753 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0170949 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0169745 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0168855 |
| TLE4 | transducin-like enhancer of split 4 | 0.016848 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.0168119 |
| EREG | epiregulin | 0.016775 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.0163954 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.016367 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0163521 |
| SLMAP | sarcolemma associated protein | 0.0163464 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0163155 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0161431 |
| FAM135A | family with sequence similarity 135, member A | 0.0161162 |
| C3ORF52 | chromosome 3 open reading frame 52 | 0.0160343 |
| USP3 | ubiquitin specific peptidase 3 | 0.0157867 |
| STX3 | syntaxin 3 | 0.0156338 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0156125 |
| SGMS2 | sphingomyelin synthase 2 | 0.0156067 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0153416 |
| KITLG | KIT ligand | 0.0152694 |
| SDCBP | syndecan binding protein (syntenin) | 0.0151418 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0149389 |
| MIMS1 | mitochondrial inner membrane scaffold 1 | 0.0149249 |
| UBQLN1 | ubiquilin 1 | 0.0149197 |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | 0.0147879 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0147229 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0146717 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0146553 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0145962 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0145339 |
| PRR5L | proline rich 5 like | 0.0144842 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0144536 |
| ELOVL7 | ELOVL fatty acid elongase 7 | 0.0144391 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0142805 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0142712 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS6 | ribosomal protein S6 | -0.161759 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.139301 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.135013 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.13234 |
| PTMA | prothymosin, alpha | -0.117443 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.114284 |
| NDRG1 | N-myc downstream regulated 1 | -0.104225 |
| FTL | ferritin, light polypeptide | -0.0965778 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0963043 |
| RPLP1 | ribosomal protein, large, P1 | -0.0942651 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0889052 |
| LYZ | lysozyme | -0.0867039 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.086227 |
| TMSB10 | thymosin beta 10 | -0.086094 |
| RPS19 | ribosomal protein S19 | -0.0848208 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.0796858 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0794915 |
| RPS8 | ribosomal protein S8 | -0.078987 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0773958 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0769286 |
| WASF2 | WAS protein family, member 2 | -0.0752684 |
| ACTN4 | actinin, alpha 4 | -0.0745915 |
| FRY | furry homolog (Drosophila) | -0.0731905 |
| RPL23 | ribosomal protein L23 | -0.0717502 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0693057 |
| RPLP2 | ribosomal protein, large, P2 | -0.0671689 |
| BPTF | bromodomain PHD finger transcription factor | -0.0651625 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0635832 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0633641 |
| AGR2 | anterior gradient 2 | -0.0612769 |
| RPS3 | ribosomal protein S3 | -0.0597932 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0591806 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0583099 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0576739 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0571736 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0559391 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0557364 |
| ACTG1 | actin gamma 1 | -0.0556386 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0555747 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0554403 |
| EGR1 | early growth response 1 | -0.0538879 |
| RPL13A | ribosomal protein L13a | -0.0530271 |
| RPS12 | ribosomal protein S12 | -0.0523368 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0516581 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0510668 |
| RPS13 | ribosomal protein S13 | -0.0509832 |
| RPS11 | ribosomal protein S11 | -0.0493369 |
| NECTIN2 | nectin cell adhesion molecule 2 | -0.049094 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0488588 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.048457 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0476931 |
| ANXA2 | annexin A2 | -0.0474366 |
| TMC5 | transmembrane channel-like 5 | -0.0468395 |
| SLC45A4 | solute carrier family 45, member 4 | -0.0467444 |
| JUP | junction plakoglobin | -0.046258 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0460589 |
| RSF1 | remodeling and spacing factor 1 | -0.045849 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0454735 |
| RPL35A | ribosomal protein L35a | -0.0453278 |
| RPL28 | ribosomal protein L28 | -0.0452626 |
| RPS23 | ribosomal protein S23 | -0.045033 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0448718 |
| RPS25 | ribosomal protein S25 | -0.0448124 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0443574 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0441665 |
| DNM2 | dynamin 2 | -0.0439614 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0432754 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.043088 |
| AHNAK | AHNAK nucleoprotein | -0.0429047 |
| HM13 | histocompatibility (minor) 13 | -0.042842 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0425682 |
| CUX1 | cut-like homeobox 1 | -0.0424166 |
| PCED1B | PC-esterase domain containing 1B | -0.0423806 |
| RPL37A | ribosomal protein L37a | -0.0423676 |
| DIAPH2 | diaphanous-related formin 2 | -0.0422224 |
| RPL31 | ribosomal protein L31 | -0.0421187 |
| RPL34 | ribosomal protein L34 | -0.0420066 |
| PRELID2 | PRELI domain containing 2 | -0.0418641 |
| RPS16 | ribosomal protein S16 | -0.0412879 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | -0.0412813 |
| HDLBP | high density lipoprotein binding protein | -0.0411516 |
| CANX | calnexin | -0.0407518 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0404678 |
| PKM | pyruvate kinase, muscle | -0.040342 |
| KRT20 | keratin 20, type I | -0.0400396 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0399781 |
| KRT19 | keratin 19, type I | -0.0398361 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0394734 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0393826 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0390107 |
| RPS27 | ribosomal protein S27 | -0.0386283 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0383923 |
| ASTN2 | astrotactin 2 | -0.0383272 |
| GOLGB1 | golgin B1 | -0.0382953 |
| RPS17 | ribosomal protein S17 | -0.0373546 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | -0.0373117 |
| STK24 | serine/threonine kinase 24 | -0.037043 |
| S100A6 | S100 calcium binding protein A6 | -0.0364873 |
| RPL27A | ribosomal protein L27a | -0.03648 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0364165 |
