| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | c-Kit-IN-1 perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the c-Kit-IN-1_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SLTM | SAFB-like, transcription modulator | 0.135302 |
| NDRG1 | N-myc downstream regulated 1 | 0.122404 |
| USP3 | ubiquitin specific peptidase 3 | 0.0953592 |
| FNIP1 | folliculin interacting protein 1 | 0.0928418 |
| RYBP | RING1 and YY1 binding protein | 0.0914086 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0900111 |
| ANXA2 | annexin A2 | 0.0889862 |
| NPTN | neuroplastin | 0.0889287 |
| GOLGA4 | golgin A4 | 0.0879848 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0871597 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0853205 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0852669 |
| KRT17 | keratin 17, type I | 0.0789472 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0788101 |
| RPL11 | ribosomal protein L11 | 0.0778203 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0717103 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0717014 |
| RLF | rearranged L-myc fusion | 0.0685055 |
| LAMB3 | laminin, beta 3 | 0.0678135 |
| SON | SON DNA binding protein | 0.0670981 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | 0.0669213 |
| FUS | FUS RNA binding protein | 0.0665423 |
| AGO3 | argonaute RISC catalytic component 3 | 0.0658605 |
| DTNA | dystrobrevin, alpha | 0.0657272 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.065311 |
| PTEN | phosphatase and tensin homolog | 0.0639195 |
| CCNL1 | cyclin L1 | 0.0634259 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0627437 |
| RPL37A | ribosomal protein L37a | 0.0619227 |
| SRPK2 | SRSF protein kinase 2 | 0.0618218 |
| GPHN | gephyrin | 0.0612559 |
| JUN | jun proto-oncogene | 0.0611081 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0606904 |
| LDHA | lactate dehydrogenase A | 0.0597797 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0594595 |
| RTN4 | reticulon 4 | 0.0589362 |
| PUM1 | pumilio RNA-binding family member 1 | 0.058659 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0586545 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0573844 |
| NBAS | neuroblastoma amplified sequence | 0.0571874 |
| NGLY1 | N-glycanase 1 | 0.0564833 |
| NAA15 | N(alpha)-acetyltransferase 15, NatA auxiliary subunit | 0.0563196 |
| SNX9 | sorting nexin 9 | 0.0562998 |
| ANXA1 | annexin A1 | 0.0555631 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.0526691 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0526389 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0522167 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0517739 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0512135 |
| FOXO3 | forkhead box O3 | 0.0508704 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0506229 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0502129 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0501506 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0501232 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0491517 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0485978 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.048548 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0483779 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0482432 |
| DDX56 | DEAD (Asp-Glu-Ala-Asp) box helicase 56 | 0.0481449 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0481025 |
| SMAD3 | SMAD family member 3 | 0.0473449 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0470525 |
| RPL23 | ribosomal protein L23 | 0.0465895 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0447873 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0444686 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0443577 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0442989 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0438547 |
| JMJD1C | jumonji domain containing 1C | 0.0437265 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.04344 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0424664 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | 0.0422818 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0421118 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0420109 |
| PLEC | plectin | 0.0417097 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0414951 |
| ZNF292 | zinc finger protein 292 | 0.0400123 |
| HELZ | helicase with zinc finger | 0.0380307 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0378878 |
| QKI | QKI, KH domain containing, RNA binding | 0.0376122 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0375153 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.0367698 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0366759 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0360872 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.035625 |
| RUNX1 | runt-related transcription factor 1 | 0.0354561 |
| BRD2 | bromodomain containing 2 | 0.0352845 |
| MYO5B | myosin VB | 0.0344375 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0340344 |
| DSPP | dentin sialophosphoprotein | 0.0338192 |
| FMNL2 | formin-like 2 | 0.0337192 |
| EGFR | epidermal growth factor receptor | 0.0332641 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0330283 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0325182 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0322089 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0319427 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0314633 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0312009 |
| ACTG1 | actin gamma 1 | 0.0309013 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.128612 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.12373 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.108904 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0963883 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0908551 |
| FTL | ferritin, light polypeptide | -0.0842936 |
| ENO1 | enolase 1, (alpha) | -0.0818197 |
| VIM | vimentin | -0.0786938 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0760165 |
| TMSB10 | thymosin beta 10 | -0.075799 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0726368 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0714782 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0703131 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0700479 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0697053 |
| RIGI | RNA sensor RIG-I | -0.069066 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0680584 |
| S100A9 | S100 calcium binding protein A9 | -0.0675543 |
| TPM4 | tropomyosin 4 | -0.0670897 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0661657 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.065759 |
| GOLGB1 | golgin B1 | -0.0656055 |
| BPTF | bromodomain PHD finger transcription factor | -0.0649823 |
| B2M | beta-2-microglobulin | -0.0647466 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0633777 |
| MYOF | myoferlin | -0.0627319 |
| LMO7 | LIM domain 7 | -0.062039 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0583693 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0583216 |
| RORA | RAR-related orphan receptor A | -0.0577222 |
| THBS1 | thrombospondin 1 | -0.0572836 |
| GPC6 | glypican 6 | -0.055996 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0555345 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0552114 |
| NBEA | neurobeachin | -0.0550115 |
| EFNA5 | ephrin-A5 | -0.0549409 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0547252 |
| FLNB | filamin B, beta | -0.0545875 |
| FAT1 | FAT atypical cadherin 1 | -0.0539712 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0539605 |
| EXOC4 | exocyst complex component 4 | -0.0534926 |
| PARD3 | par-3 family cell polarity regulator | -0.0531784 |
| NRG1 | neuregulin 1 | -0.0523521 |
| PDE10A | phosphodiesterase 10A | -0.0513413 |
| KYNU | kynureninase | -0.0505903 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0505172 |
| ASPH | aspartate beta-hydroxylase | -0.0501175 |
| PERP | PERP, TP53 apoptosis effector | -0.0498444 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0480475 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.047538 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0473346 |
| MED13L | mediator complex subunit 13-like | -0.0464275 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0460587 |
| ERBIN | erbb2 interacting protein | -0.0459843 |
| RNF213 | ring finger protein 213 | -0.0459133 |
| AHNAK | AHNAK nucleoprotein | -0.0452099 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0449991 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0446685 |
| ABHD17C | abhydrolase domain containing 17C | -0.0437935 |
| FOXP1 | forkhead box P1 | -0.0430195 |
| SMYD3 | SET and MYND domain containing 3 | -0.0428625 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0416058 |
| TANK | TRAF family member-associated NFKB activator | -0.0413867 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.041355 |
| NUMB | numb homolog (Drosophila) | -0.0401781 |
| STK17A | serine/threonine kinase 17a | -0.0396724 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0395665 |
| PTMA | prothymosin, alpha | -0.0390468 |
| RAI14 | retinoic acid induced 14 | -0.0388357 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0384366 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0384048 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0382284 |
| ZNF638 | zinc finger protein 638 | -0.0382214 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.0381418 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.037847 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | -0.0369898 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0367183 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0366069 |
| ATOSA | atos homolog A | -0.036475 |
| RUFY1 | RUN and FYVE domain containing 1 | -0.0361269 |
| MAPK6 | mitogen-activated protein kinase 6 | -0.0359907 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0358345 |
| RPS27A | ribosomal protein S27a | -0.0356667 |
| USP53 | ubiquitin specific peptidase 53 | -0.0354827 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0353604 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0351343 |
| CCNI | cyclin I | -0.0347398 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0347103 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0345458 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0344219 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0342805 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0342382 |
| NEBL | nebulette | -0.0338496 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0335913 |
| RPL31 | ribosomal protein L31 | -0.0328461 |
| PRELID2 | PRELI domain containing 2 | -0.032839 |
| STC1 | stanniocalcin 1 | -0.0326737 |
| RPL35A | ribosomal protein L35a | -0.0326095 |
| CEP350 | centrosomal protein 350kDa | -0.032564 |
| KIAA1671 | KIAA1671 | -0.031345 |
