| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | c-Kit-IN-1 perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the c-Kit-IN-1_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.119674 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.113059 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.104351 |
| ASPH | aspartate beta-hydroxylase | 0.0960097 |
| TXNRD1 | thioredoxin reductase 1 | 0.0944811 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0888146 |
| GRAMD1B | GRAM domain containing 1B | 0.0812592 |
| PDE10A | phosphodiesterase 10A | 0.0781249 |
| MCL1 | myeloid cell leukemia 1 | 0.0766837 |
| MYOF | myoferlin | 0.071328 |
| CD109 | CD109 molecule | 0.0704064 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0696028 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0653407 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0649346 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0633492 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0613043 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0601605 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0599624 |
| FMNL2 | formin-like 2 | 0.0589545 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0583879 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0582902 |
| EZR | ezrin | 0.0577021 |
| TBXT | T-box transcription factor T | 0.055282 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.054936 |
| KYNU | kynureninase | 0.0543196 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0540455 |
| FLNB | filamin B, beta | 0.0536761 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0516881 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0510565 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0502675 |
| GDA | guanine deaminase | 0.0486526 |
| SPAG9 | sperm associated antigen 9 | 0.0475826 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.0446141 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0437235 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0433518 |
| PALLD | palladin, cytoskeletal associated protein | 0.0425549 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0423074 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0420434 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.041419 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0409234 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0402735 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0399531 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0387422 |
| MSN | moesin | 0.0386044 |
| SFTPA2 | surfactant protein A2 | 0.0375118 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0369503 |
| PTK2 | protein tyrosine kinase 2 | 0.0359596 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0359461 |
| CENPF | centromere protein F, 350/400kDa | 0.0358799 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0353114 |
| PTEN | phosphatase and tensin homolog | 0.0352471 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0347045 |
| PCBP2 | poly(rC) binding protein 2 | 0.0345826 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0341599 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0337702 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0334383 |
| ANXA2 | annexin A2 | 0.0333984 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0332708 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0326797 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0326747 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0324109 |
| CTBP2 | C-terminal binding protein 2 | 0.0323399 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0317775 |
| ZNF638 | zinc finger protein 638 | 0.0316772 |
| EFNA5 | ephrin-A5 | 0.0314845 |
| NBAS | neuroblastoma amplified sequence | 0.0314474 |
| USP34 | ubiquitin specific peptidase 34 | 0.031376 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0312689 |
| CUL4A | cullin 4A | 0.0311096 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0308814 |
| HELZ | helicase with zinc finger | 0.0305638 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0305593 |
| CDK6 | cyclin-dependent kinase 6 | 0.0303425 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0302014 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0300884 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0299348 |
| NDRG1 | N-myc downstream regulated 1 | 0.0296303 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0287796 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.0287034 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0286848 |
| ANO6 | anoctamin 6 | 0.0284046 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0281413 |
| MATR3 | matrin 3 | 0.0280911 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0279868 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.027905 |
| B2M | beta-2-microglobulin | 0.0278716 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.027787 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0277052 |
| NCKAP1 | NCK-associated protein 1 | 0.0275109 |
| MKI67 | marker of proliferation Ki-67 | 0.0274293 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0273317 |
| FAM13A | family with sequence similarity 13, member A | 0.0263612 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0263512 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0260921 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0260098 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.0258129 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0257329 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0257168 |
| IL6 | interleukin 6 | 0.0256425 |
| XPO1 | exportin 1 | 0.0255365 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.380753 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.147259 |
| FN1 | fibronectin 1 | -0.139924 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.100621 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0996603 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0831525 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0774536 |
| RPL26 | ribosomal protein L26 | -0.0760908 |
| PCBP3 | poly(rC) binding protein 3 | -0.074338 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0733648 |
| VCL | vinculin | -0.0663234 |
| RPL12 | ribosomal protein L12 | -0.0560994 |
| RPL31 | ribosomal protein L31 | -0.0542151 |
| RPS24 | ribosomal protein S24 | -0.0531567 |
| ACTG1 | actin gamma 1 | -0.0522349 |
| RPS3 | ribosomal protein S3 | -0.0521431 |
| RPS27A | ribosomal protein S27a | -0.0518748 |
| ADGRD1 | adhesion G protein-coupled receptor D1 | -0.0513309 |
| RPL37A | ribosomal protein L37a | -0.0508279 |
| CDH13 | cadherin 13 | -0.0488309 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0477887 |
| RPS12 | ribosomal protein S12 | -0.0462016 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0459806 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0442244 |
| FTL | ferritin, light polypeptide | -0.0440598 |
| RPS6 | ribosomal protein S6 | -0.0427407 |
| RPL38 | ribosomal protein L38 | -0.0412266 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0403885 |
| NCKAP5 | NCK-associated protein 5 | -0.0402405 |
| PTMA | prothymosin, alpha | -0.0395582 |
| RPL9 | ribosomal protein L9 | -0.0377395 |
| RPLP1 | ribosomal protein, large, P1 | -0.0376508 |
| RACK1 | receptor for activated C kinase 1 | -0.0368627 |
| RPL11 | ribosomal protein L11 | -0.0363817 |
| RPL13A | ribosomal protein L13a | -0.0357902 |
| RPS17 | ribosomal protein S17 | -0.0354898 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0354306 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0352612 |
| RPLP0 | ribosomal protein, large, P0 | -0.0341639 |
| RPL19 | ribosomal protein L19 | -0.0335687 |
| RPS23 | ribosomal protein S23 | -0.0334626 |
| DST | dystonin | -0.0333322 |
| RPL37 | ribosomal protein L37 | -0.033284 |
| RPS29 | ribosomal protein S29 | -0.033118 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0327804 |
| RPS8 | ribosomal protein S8 | -0.0322401 |
| RPL35 | ribosomal protein L35 | -0.0316213 |
| PRELID2 | PRELI domain containing 2 | -0.0315999 |
| NOP56 | NOP56 ribonucleoprotein | -0.0314787 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0306663 |
| RPL34 | ribosomal protein L34 | -0.0306019 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.030126 |
| TENM3 | teneurin transmembrane protein 3 | -0.0294883 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0290205 |
| RPL35A | ribosomal protein L35a | -0.0289233 |
| RPS2 | ribosomal protein S2 | -0.0285098 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0284545 |
| RTN1 | reticulon 1 | -0.0271392 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.026814 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0258068 |
| ESM1 | endothelial cell-specific molecule 1 | -0.0257712 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0254415 |
| RPLP2 | ribosomal protein, large, P2 | -0.0249451 |
| NRCAM | neuronal cell adhesion molecule | -0.0248897 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0248381 |
| RPS25 | ribosomal protein S25 | -0.0246134 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0242524 |
| CCDC68 | coiled-coil domain containing 68 | -0.0239852 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0237483 |
| CTNND2 | catenin (cadherin-associated protein), delta 2 | -0.0233607 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | -0.0230423 |
| PA2G4 | proliferation-associated 2G4, 38kDa | -0.0228801 |
| RPL22L1 | ribosomal protein L22-like 1 | -0.0227019 |
| RPS13 | ribosomal protein S13 | -0.0225136 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.022155 |
| GLCCI1 | glucocorticoid induced 1 | -0.0217182 |
| RPS21 | ribosomal protein S21 | -0.0217107 |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit | -0.0216862 |
| RPL23 | ribosomal protein L23 | -0.0215685 |
| RPS5 | ribosomal protein S5 | -0.0215544 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0213567 |
| TPM4 | tropomyosin 4 | -0.0211884 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0210522 |
| DNAH11 | dynein, axonemal, heavy chain 11 | -0.0210192 |
| RPL27 | ribosomal protein L27 | -0.0205914 |
| RPL30 | ribosomal protein L30 | -0.0204678 |
| AEBP2 | AE binding protein 2 | -0.0201402 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0197342 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | -0.0196291 |
| PCDH9 | protocadherin 9 | -0.0193345 |
| GABRE | gamma-aminobutyric acid (GABA) A receptor, epsilon | -0.0192955 |
| INTS6 | integrator complex subunit 6 | -0.0192142 |
| VDAC1 | voltage-dependent anion channel 1 | -0.019097 |
| CANX | calnexin | -0.0190787 |
| SLC16A6 | solute carrier family 16, member 6 | -0.0186571 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.0185829 |
| HMGA2 | high mobility group AT-hook 2 | -0.0184994 |
| RPS14 | ribosomal protein S14 | -0.0184739 |
| RPS10 | ribosomal protein S10 | -0.0184606 |
| RPS15 | ribosomal protein S15 | -0.0183576 |
