| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | c-Kit-IN-1 perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the c-Kit-IN-1_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.158484 |
| DST | dystonin | 0.155009 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.1442 |
| WDR43 | WD repeat domain 43 | 0.0941416 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.088668 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0847448 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0843832 |
| ANK2 | ankyrin 2, neuronal | 0.0819278 |
| COL11A1 | collagen, type XI, alpha 1 | 0.075766 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.074356 |
| PGAP1 | post-GPI attachment to proteins 1 | 0.0681294 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0621619 |
| APP | amyloid beta (A4) precursor protein | 0.0613328 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0589942 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.057567 |
| NOP58 | NOP58 ribonucleoprotein | 0.0572662 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0548183 |
| TENM3 | teneurin transmembrane protein 3 | 0.0538678 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0529025 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.051267 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | 0.0505537 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.0493932 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.048608 |
| NCKAP1 | NCK-associated protein 1 | 0.0485876 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.047425 |
| LRRC4C | leucine rich repeat containing 4C | 0.0471633 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0462529 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0449431 |
| DDX56 | DEAD (Asp-Glu-Ala-Asp) box helicase 56 | 0.044772 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0442715 |
| ITGAV | integrin, alpha V | 0.0441628 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0427062 |
| SPAG9 | sperm associated antigen 9 | 0.0419139 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0417596 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0416479 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0409486 |
| GOLGA4 | golgin A4 | 0.0404959 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0404761 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0396668 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0396473 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0393339 |
| NTM | neurotrimin | 0.0392717 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0390667 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0382464 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0376813 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0375192 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0373282 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | 0.0368346 |
| OLA1 | Obg-like ATPase 1 | 0.0366309 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0361712 |
| NUP153 | nucleoporin 153kDa | 0.0354568 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | 0.0353994 |
| CALR | calreticulin | 0.035291 |
| TPM3 | tropomyosin 3 | 0.03526 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0349797 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.034531 |
| AHCTF1 | AT hook containing transcription factor 1 | 0.0344818 |
| NAA15 | N(alpha)-acetyltransferase 15, NatA auxiliary subunit | 0.0344454 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0342769 |
| SRPK2 | SRSF protein kinase 2 | 0.0342611 |
| MDN1 | MDN1, midasin homolog (yeast) | 0.033956 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0336703 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0332141 |
| SMYD3 | SET and MYND domain containing 3 | 0.0331753 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0329697 |
| FNBP1L | formin binding protein 1-like | 0.0328974 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0325659 |
| LHFPL6 | LHFPL tetraspan subfamily member 6 | 0.0322184 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0318866 |
| FIP1L1 | factor interacting with PAPOLA and CPSF1 | 0.0317118 |
| TARS1 | threonyl-tRNA synthetase 1 | 0.0313927 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | 0.0313665 |
| CADM2 | cell adhesion molecule 2 | 0.0309725 |
| TNPO1 | transportin 1 | 0.0305358 |
| MYO10 | myosin X | 0.0305001 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0303444 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0301227 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.029751 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.029662 |
| RLF | rearranged L-myc fusion | 0.0295149 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0295095 |
| ACACA | acetyl-CoA carboxylase alpha | 0.0294736 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0291893 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0291703 |
| LARP4 | La ribonucleoprotein domain family, member 4 | 0.0290972 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0290241 |
| PCNX1 | pecanex 1 | 0.0290217 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | 0.0290175 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.028988 |
| AGO3 | argonaute RISC catalytic component 3 | 0.028958 |
| SCAF4 | SR-related CTD-associated factor 4 | 0.0287241 |
| IPO7 | importin 7 | 0.0285628 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0284895 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0284284 |
| PUM3 | pumilio RNA binding family member 3 | 0.0281825 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0281106 |
| PAPOLA | poly(A) polymerase alpha | 0.0279724 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0279246 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0278242 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0278185 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.211056 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0914084 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0805489 |
| POTEF | POTE ankyrin domain family, member F | -0.0735811 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0673617 |
| TMSB10 | thymosin beta 10 | -0.0608991 |
| PHIP | pleckstrin homology domain interacting protein | -0.0570763 |
| PTMA | prothymosin, alpha | -0.0551187 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0545974 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0545785 |
| PFN1 | profilin 1 | -0.0537708 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0528097 |
| CENPF | centromere protein F, 350/400kDa | -0.0527684 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0510468 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0455845 |
| EMP1 | epithelial membrane protein 1 | -0.0454351 |
| PCDH9 | protocadherin 9 | -0.0437181 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.0420623 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0420028 |
| SOX2 | SRY (sex determining region Y)-box 2 | -0.0409155 |
| WASF2 | WAS protein family, member 2 | -0.0390134 |
| RPS6 | ribosomal protein S6 | -0.038496 |
| RPLP1 | ribosomal protein, large, P1 | -0.037731 |
| TMSB4X | thymosin beta 4, X-linked | -0.0368598 |
| EAPP | E2F-associated phosphoprotein | -0.036283 |
| FTL | ferritin, light polypeptide | -0.0361024 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0360222 |
| ACTG1 | actin gamma 1 | -0.0358739 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0357655 |
| ZNF217 | zinc finger protein 217 | -0.0356353 |
| TUBA1B | tubulin, alpha 1b | -0.0355597 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.0350165 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0344335 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.03437 |
| DEK | DEK proto-oncogene | -0.0343607 |
| NEK7 | NIMA-related kinase 7 | -0.0340946 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0335275 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0334942 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0326976 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0326724 |
| HMGA1 | high mobility group AT-hook 1 | -0.0326637 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0322583 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0317668 |
| SERINC1 | serine incorporator 1 | -0.0307553 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0306231 |
| RPS16 | ribosomal protein S16 | -0.0306115 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.0304072 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0302418 |
| SYT1 | synaptotagmin I | -0.0302225 |
| HMGB2 | high mobility group box 2 | -0.0299041 |
| RFPL4B | ret finger protein-like 4B | -0.0290405 |
| PDGFC | platelet derived growth factor C | -0.0290248 |
| FN1 | fibronectin 1 | -0.0290012 |
| MEIS2 | Meis homeobox 2 | -0.0281937 |
| TOX | thymocyte selection-associated high mobility group box | -0.0276148 |
| FIGN | fidgetin | -0.0273153 |
| STAG2 | stromal antigen 2 | -0.0272966 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0272087 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0271929 |
| ZNF292 | zinc finger protein 292 | -0.0270401 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0270223 |
| RPLP0 | ribosomal protein, large, P0 | -0.026959 |
| MED13L | mediator complex subunit 13-like | -0.0266594 |
| HBP1 | HMG-box transcription factor 1 | -0.0266349 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0266139 |
| ARHGAP15 | Rho GTPase activating protein 15 | -0.0262757 |
| RPS13 | ribosomal protein S13 | -0.0262448 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0261816 |
| PHF3 | PHD finger protein 3 | -0.0260429 |
| CBX3 | chromobox homolog 3 | -0.0253673 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.025288 |
| MT2A | metallothionein 2A | -0.0250128 |
| DSTN | destrin (actin depolymerizing factor) | -0.0249721 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0249534 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0246718 |
| OSBPL9 | oxysterol binding protein-like 9 | -0.0246677 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0246243 |
| BBX | bobby sox homolog (Drosophila) | -0.0245962 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0243655 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0241389 |
| TPX2 | TPX2, microtubule-associated | -0.0241341 |
| RPL35A | ribosomal protein L35a | -0.024094 |
| PPM1B | protein phosphatase, Mg2+/Mn2+ dependent, 1B | -0.0239526 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0238813 |
| HMGB1 | high mobility group box 1 | -0.023692 |
| GPC3 | glypican 3 | -0.0233649 |
| FOXP1 | forkhead box P1 | -0.0232127 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0230654 |
| PEG10 | paternally expressed 10 | -0.0229625 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0228928 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0228082 |
| TMEM123 | transmembrane protein 123 | -0.0226534 |
| RPLP2 | ribosomal protein, large, P2 | -0.0226052 |
| OGA | O-GlcNAcase | -0.0222274 |
| B2M | beta-2-microglobulin | -0.0221174 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0220937 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.02194 |
| GNAS | GNAS complex locus | -0.0218906 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0217024 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0216912 |
