| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | c-Kit-IN-1 perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the c-Kit-IN-1_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.211679 |
| CALD1 | caldesmon 1 | 0.114747 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.10368 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0931116 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0778382 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0732044 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0704438 |
| COL5A1 | collagen, type V, alpha 1 | 0.0682024 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.065843 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0649213 |
| NRXN3 | neurexin 3 | 0.0628826 |
| PRELID2 | PRELI domain containing 2 | 0.0628245 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0560299 |
| TNNC1 | troponin C type 1 (slow) | 0.0559092 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0545969 |
| FRMD5 | FERM domain containing 5 | 0.0541928 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0516219 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0506 |
| VEGFA | vascular endothelial growth factor A | 0.0503615 |
| RUNX1 | runt-related transcription factor 1 | 0.0502389 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0485887 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0474614 |
| PDZRN3 | PDZ domain containing ring finger 3 | 0.0474515 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.047085 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0454958 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.044827 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0441926 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0429265 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0424164 |
| DST | dystonin | 0.0421979 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0416088 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0406632 |
| EGFR | epidermal growth factor receptor | 0.0405487 |
| NBAS | neuroblastoma amplified sequence | 0.0390237 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0386392 |
| HMGA2 | high mobility group AT-hook 2 | 0.0385527 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0384304 |
| ATP13A3 | ATPase type 13A3 | 0.0383422 |
| PTK2 | protein tyrosine kinase 2 | 0.0360361 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0337427 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0333295 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0328494 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.032586 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0325247 |
| MYO10 | myosin X | 0.0321723 |
| FAM219A | family with sequence similarity 219, member A | 0.0320028 |
| PDGFC | platelet derived growth factor C | 0.0314659 |
| FNDC3B | fibronectin type III domain containing 3B | 0.031281 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.031214 |
| LAMB1 | laminin, beta 1 | 0.0306344 |
| FNIP1 | folliculin interacting protein 1 | 0.0305032 |
| HDAC9 | histone deacetylase 9 | 0.0299655 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0295081 |
| SYTL2 | synaptotagmin-like 2 | 0.0293861 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0289674 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0288136 |
| STK17A | serine/threonine kinase 17a | 0.0285368 |
| RYBP | RING1 and YY1 binding protein | 0.0283186 |
| TARS1 | threonyl-tRNA synthetase 1 | 0.0280686 |
| NAV2 | neuron navigator 2 | 0.0279861 |
| MSI2 | musashi RNA-binding protein 2 | 0.0277895 |
| CORO1C | coronin, actin binding protein, 1C | 0.0276559 |
| NGLY1 | N-glycanase 1 | 0.0274959 |
| FLNA | filamin A, alpha | 0.0273325 |
| STC2 | stanniocalcin 2 | 0.0272855 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0271114 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0270831 |
| CUL3 | cullin 3 | 0.0269191 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.026717 |
| ZNF638 | zinc finger protein 638 | 0.0263059 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0262475 |
| PGK1 | phosphoglycerate kinase 1 | 0.0261483 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.025962 |
| WWOX | WW domain containing oxidoreductase | 0.0257848 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0250988 |
| PLEC | plectin | 0.0249375 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0249098 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0243548 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0238587 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0237785 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0236048 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0228435 |
| SLTM | SAFB-like, transcription modulator | 0.0228141 |
| NUP58 | nucleoporin 58 | 0.02275 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0227111 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.0226156 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0225998 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0225345 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0225058 |
| ANXA5 | annexin A5 | 0.022282 |
| FAT1 | FAT atypical cadherin 1 | 0.022252 |
| MAP4 | microtubule-associated protein 4 | 0.0221336 |
| TOP1 | topoisomerase (DNA) I | 0.0221215 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0218985 |
| MSN | moesin | 0.0217762 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0217572 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0217092 |
| SNX13 | sorting nexin 13 | 0.0217035 |
| FBN1 | fibrillin 1 | 0.0216366 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0215212 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.318912 |
| MT2A | metallothionein 2A | -0.247503 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.187776 |
| TMSB10 | thymosin beta 10 | -0.18339 |
| VIM | vimentin | -0.163662 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.130826 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.129089 |
| HLA-B | major histocompatibility complex, class I, B | -0.121175 |
| B2M | beta-2-microglobulin | -0.105133 |
| PTMA | prothymosin, alpha | -0.0901836 |
| FTL | ferritin, light polypeptide | -0.0849954 |
| COL1A1 | collagen, type I, alpha 1 | -0.0782655 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.075911 |
| PRSS23 | protease, serine, 23 | -0.0710351 |
| SDC4 | syndecan 4 | -0.0705538 |
| COL1A2 | collagen, type I, alpha 2 | -0.0679628 |
| HLA-A | major histocompatibility complex, class I, A | -0.0665931 |
| STC1 | stanniocalcin 1 | -0.0644643 |
| HLA-C | major histocompatibility complex, class I, C | -0.0628218 |
| LOX | lysyl oxidase | -0.0590784 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0535804 |
| OGA | O-GlcNAcase | -0.0526317 |
| LOXL2 | lysyl oxidase-like 2 | -0.05231 |
| UBC | ubiquitin C | -0.0517478 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0493503 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0486061 |
| MT1X | metallothionein 1X | -0.0482273 |
| S100A10 | S100 calcium binding protein A10 | -0.046747 |
| CCNI | cyclin I | -0.046366 |
| CD44 | CD44 molecule (Indian blood group) | -0.0446176 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0430908 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0418071 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0417499 |
| CAVIN1 | caveolae associated protein 1 | -0.0412059 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0410923 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0410073 |
| H3-3B | H3.3 histone B | -0.040174 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0401484 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0401239 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0389302 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0388343 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0383402 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0368034 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0366769 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0363286 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0360649 |
| RPLP1 | ribosomal protein, large, P1 | -0.0356182 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0355189 |
| MYOF | myoferlin | -0.0354266 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0350103 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0346789 |
| S100A9 | S100 calcium binding protein A9 | -0.0343527 |
| POTEF | POTE ankyrin domain family, member F | -0.0342171 |
| HM13 | histocompatibility (minor) 13 | -0.0339603 |
| GNAS | GNAS complex locus | -0.0336624 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0329803 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0323281 |
| TXNIP | thioredoxin interacting protein | -0.0319658 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0316793 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0304554 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0303286 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.029593 |
| ARF1 | ADP-ribosylation factor 1 | -0.0293569 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0290929 |
| RPL28 | ribosomal protein L28 | -0.0290735 |
| SEPTIN7 | septin 7 | -0.0290151 |
| WASF2 | WAS protein family, member 2 | -0.0288994 |
| HBP1 | HMG-box transcription factor 1 | -0.0288609 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0287585 |
| HMGB1 | high mobility group box 1 | -0.0287447 |
| THY1 | Thy-1 cell surface antigen | -0.0287009 |
| CD99 | CD99 molecule | -0.0280956 |
| RPL34 | ribosomal protein L34 | -0.0279963 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0279034 |
| NAV1 | neuron navigator 1 | -0.0276156 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0274187 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0272411 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0270733 |
| HDLBP | high density lipoprotein binding protein | -0.0268811 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0266459 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0265628 |
| S100A6 | S100 calcium binding protein A6 | -0.0265612 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0263931 |
| SRGN | serglycin | -0.0261454 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0259308 |
| CST3 | cystatin C | -0.0256209 |
| HIP1 | huntingtin interacting protein 1 | -0.0256105 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0254895 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0251105 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0246198 |
| LAMB3 | laminin, beta 3 | -0.0243981 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0242587 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0241862 |
| HMGB2 | high mobility group box 2 | -0.0241793 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.023801 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0237114 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0235546 |
| ADM | adrenomedullin | -0.0233263 |
| RPS5 | ribosomal protein S5 | -0.0231724 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0229503 |
