| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | c-Kit-IN-1 perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the c-Kit-IN-1_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0971637 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0934452 |
| GOLGA4 | golgin A4 | 0.0676198 |
| FNIP1 | folliculin interacting protein 1 | 0.0665061 |
| NUP58 | nucleoporin 58 | 0.0651342 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.065084 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0643253 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0602222 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0599438 |
| DTNA | dystrobrevin, alpha | 0.056386 |
| GPC6 | glypican 6 | 0.0542435 |
| MAP1B | microtubule-associated protein 1B | 0.0532201 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0530226 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0489184 |
| ARFGEF3 | ARFGEF family member 3 | 0.0477345 |
| PRELID2 | PRELI domain containing 2 | 0.043741 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.043438 |
| CLTC | clathrin, heavy chain (Hc) | 0.0433451 |
| SEC24A | SEC24 family member A | 0.0432452 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0411176 |
| SET | SET nuclear proto-oncogene | 0.0407124 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0406206 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | 0.040599 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0394086 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0386459 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0375362 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0374035 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0366077 |
| WDR43 | WD repeat domain 43 | 0.0359397 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0352395 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0350246 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0343767 |
| IPO7 | importin 7 | 0.0338251 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0337945 |
| ATP13A3 | ATPase type 13A3 | 0.0337752 |
| NGLY1 | N-glycanase 1 | 0.0323694 |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 | 0.0323158 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0315526 |
| LDHA | lactate dehydrogenase A | 0.0308855 |
| SNX14 | sorting nexin 14 | 0.030757 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0306386 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0305652 |
| CEP250 | centrosomal protein 250kDa | 0.030407 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0295494 |
| PANK3 | pantothenate kinase 3 | 0.0294961 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | 0.0291918 |
| AARS1 | alanyl-tRNA synthetase 1 | 0.0291586 |
| NBAS | neuroblastoma amplified sequence | 0.0288664 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0284092 |
| SEPTIN10 | septin 10 | 0.0280963 |
| ASPH | aspartate beta-hydroxylase | 0.0280578 |
| TARS1 | threonyl-tRNA synthetase 1 | 0.0274866 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0274249 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0268811 |
| TXNRD1 | thioredoxin reductase 1 | 0.0267065 |
| TM9SF4 | transmembrane 9 superfamily protein member 4 | 0.0265722 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0264492 |
| DDX56 | DEAD (Asp-Glu-Ala-Asp) box helicase 56 | 0.0263501 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0262297 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0259308 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0258728 |
| XPOT | exportin, tRNA | 0.0257544 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0256793 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0256547 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0254623 |
| CAPRIN1 | cell cycle associated protein 1 | 0.0242888 |
| TFRC | transferrin receptor | 0.0242765 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0242342 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0239282 |
| TNPO1 | transportin 1 | 0.0237496 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.023306 |
| TPM3 | tropomyosin 3 | 0.0232566 |
| PCBP2 | poly(rC) binding protein 2 | 0.0231598 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.0229958 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0229626 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0227852 |
| FLNB | filamin B, beta | 0.02256 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.022516 |
| SPAG9 | sperm associated antigen 9 | 0.0225057 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0224885 |
| LARS1 | leucyl-tRNA synthetase 1 | 0.0223464 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0220109 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0218541 |
| NSUN2 | NOP2/Sun RNA methyltransferase family, member 2 | 0.021809 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0217405 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0217037 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0215417 |
| GPATCH2L | G patch domain containing 2-like | 0.0213895 |
| NPTN | neuroplastin | 0.0213844 |
| SFXN1 | sideroflexin 1 | 0.0213667 |
| C1GALT1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | 0.0213486 |
| CASC3 | cancer susceptibility candidate 3 | 0.0213424 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0213024 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0212507 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0212229 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0210806 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.020868 |
| LHFPL6 | LHFPL tetraspan subfamily member 6 | 0.0205105 |
| SEC24D | SEC24 family member D | 0.020482 |
| SCFD1 | sec1 family domain containing 1 | 0.0204687 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.382749 |
| VIM | vimentin | -0.183063 |
| TMSB10 | thymosin beta 10 | -0.171721 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0908538 |
| MT2A | metallothionein 2A | -0.0902794 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0745697 |
| PTMA | prothymosin, alpha | -0.0725458 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0686239 |
| CD44 | CD44 molecule (Indian blood group) | -0.0675809 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0647803 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0628224 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0627578 |
| RPLP1 | ribosomal protein, large, P1 | -0.0615846 |
| YBX3 | Y box binding protein 3 | -0.0614557 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0597363 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0596041 |
| HMGA2 | high mobility group AT-hook 2 | -0.0565328 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0553817 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0551037 |
| IGF2 | insulin-like growth factor 2 | -0.0540402 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0525718 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0497563 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0483665 |
| POTEF | POTE ankyrin domain family, member F | -0.0464775 |
| RPL35A | ribosomal protein L35a | -0.0454354 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0452809 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0450896 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0447307 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0439077 |
| CCDC91 | coiled-coil domain containing 91 | -0.0434941 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0433406 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0426579 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0426361 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0422065 |
| PKM | pyruvate kinase, muscle | -0.0416455 |
| SVIL | supervillin | -0.0414909 |
| ATXN1 | ataxin 1 | -0.0414027 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0413276 |
| RPS3 | ribosomal protein S3 | -0.04078 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.040602 |
| RPS8 | ribosomal protein S8 | -0.0405297 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0402699 |
| H3-3B | H3.3 histone B | -0.0391508 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0391484 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0387048 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0385276 |
| DEK | DEK proto-oncogene | -0.0383363 |
| DNER | delta/notch-like EGF repeat containing | -0.0377658 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0375281 |
| FMN1 | formin 1 | -0.0366028 |
| ANGPTL4 | angiopoietin-like 4 | -0.0363013 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0361187 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.036071 |
| TPI1 | triosephosphate isomerase 1 | -0.035186 |
| FTL | ferritin, light polypeptide | -0.0351348 |
| RAD51B | RAD51 paralog B | -0.0350864 |
| DYNLRB1 | dynein, light chain, roadblock-type 1 | -0.0350811 |
| EGR1 | early growth response 1 | -0.0350186 |
| B2M | beta-2-microglobulin | -0.0348519 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0341056 |
| RSF1 | remodeling and spacing factor 1 | -0.0337478 |
| PRR16 | proline rich 16 | -0.0337121 |
| S100A9 | S100 calcium binding protein A9 | -0.0337051 |
| NDRG1 | N-myc downstream regulated 1 | -0.0336758 |
| FAM3C | family with sequence similarity 3, member C | -0.0333228 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0330313 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0329548 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0328809 |
| RPS13 | ribosomal protein S13 | -0.0327916 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0325458 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0324228 |
| IER3 | immediate early response 3 | -0.032122 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0313911 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.031369 |
| RIGI | RNA sensor RIG-I | -0.0312367 |
| RPS12 | ribosomal protein S12 | -0.0310756 |
| RPS14 | ribosomal protein S14 | -0.0305908 |
| BBX | bobby sox homolog (Drosophila) | -0.0304392 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0300906 |
| KLHL24 | kelch-like family member 24 | -0.0300804 |
| OGA | O-GlcNAcase | -0.0298529 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0298521 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0297729 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0294886 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0292644 |
| PARD3 | par-3 family cell polarity regulator | -0.0289734 |
| CWF19L2 | CWF19-like 2, cell cycle control (S. pombe) | -0.0288745 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0288228 |
| HLA-B | major histocompatibility complex, class I, B | -0.0287085 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0283988 |
| TMEM123 | transmembrane protein 123 | -0.0283505 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0282563 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0280749 |
| ATF7IP | activating transcription factor 7 interacting protein | -0.0280011 |
| CREBRF | CREB3 regulatory factor | -0.0278405 |
| RPS25 | ribosomal protein S25 | -0.0277442 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0275475 |
| RPL31 | ribosomal protein L31 | -0.0272468 |
| ACTG1 | actin gamma 1 | -0.0270135 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0266836 |
