c-Rel Gene Set

Dataset MotifMap Predicted Transcription Factor Targets
Category genomics
Type transcription factor
Description v-rel avian reticuloendotheliosis viral oncogene homolog|This gene encodes a protein that belongs to the Rel homology domain/immunoglobulin-like fold, plexin, transcription factor (RHD/IPT) family. Members of this family regulate genes involved in apoptosis, inflammation, the immune response, and oncogenic processes. This proto-oncogene plays a role in the survival and proliferation of B lymphocytes. Mutation or amplification of this gene is associated with B-cell lymphomas, including Hodgkin's lymphoma. Single nucleotide polymorphisms in this gene are associated with susceptibility to ulcerative colitis and rheumatoid arthritis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2014] (NCBI Entrez Gene Database, 5966)
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Genes

316 target genes of the c-Rel transcription factor predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.

Symbol Name
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4
ACTN3 actinin, alpha 3 (gene/pseudogene)
ADRBK2 adrenergic, beta, receptor kinase 2
ADTRP androgen-dependent TFPI-regulating protein
AGO1 argonaute RISC catalytic component 1
AHDC1 AT hook, DNA binding motif, containing 1
AHI1 Abelson helper integration site 1
AKAP13 A kinase (PRKA) anchor protein 13
ALG6 ALG6, alpha-1,3-glucosyltransferase
ANK2 ankyrin 2, neuronal
ANKRD34A ankyrin repeat domain 34A
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
ARHGAP26-AS1 ARHGAP26 antisense RNA 1
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARL14 ADP-ribosylation factor-like 14
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ATF7IP activating transcription factor 7 interacting protein
ATG16L2 autophagy related 16-like 2 (S. cerevisiae)
ATP5G1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
B2M beta-2-microglobulin
B4GALT3 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3
BCL3 B-cell CLL/lymphoma 3
BCL6B B-cell CLL/lymphoma 6, member B
BICC1 BicC family RNA binding protein 1
BIRC2 baculoviral IAP repeat containing 2
BIRC3 baculoviral IAP repeat containing 3
BMP2K BMP2 inducible kinase
BSPRY B-box and SPRY domain containing
C10ORF55 chromosome 10 open reading frame 55
C15ORF26 chromosome 15 open reading frame 26
C15ORF27 chromosome 15 open reading frame 27
CA14 carbonic anhydrase XIV
CACHD1 cache domain containing 1
CALR calreticulin
CAMTA1 calmodulin binding transcription activator 1
CBLL1 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase
CCL20 chemokine (C-C motif) ligand 20
CCSER1 coiled-coil serine-rich protein 1
CD40 CD40 molecule, TNF receptor superfamily member 5
CD82 CD82 molecule
CD86 CD86 molecule
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDH8 cadherin 8, type 2
CDK8 cyclin-dependent kinase 8
CEP152 centrosomal protein 152kDa
CEP350 centrosomal protein 350kDa
CHD2 chromodomain helicase DNA binding protein 2
CHD9 chromodomain helicase DNA binding protein 9
CLIC5 chloride intracellular channel 5
CLPTM1 cleft lip and palate associated transmembrane protein 1
CNKSR2 connector enhancer of kinase suppressor of Ras 2
COMMD3 COMM domain containing 3
COMMD3-BMI1 COMMD3-BMI1 readthrough
CREB1 cAMP responsive element binding protein 1
CREBL2 cAMP responsive element binding protein-like 2
CSF1 colony stimulating factor 1 (macrophage)
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
CSRP1 cysteine and glycine-rich protein 1
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CYLD cylindromatosis (turban tumor syndrome)
DDR1 discoidin domain receptor tyrosine kinase 1
DMD dystrophin
DMPK dystrophia myotonica-protein kinase
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DSP desmoplakin
DTX3 deltex 3, E3 ubiquitin ligase
DTX4 deltex 4, E3 ubiquitin ligase
DUSP22 dual specificity phosphatase 22
E2F5 E2F transcription factor 5, p130-binding
EDNRA endothelin receptor type A
EFCAB6 EF-hand calcium binding domain 6
EFCAB7 EF-hand calcium binding domain 7
EGFR epidermal growth factor receptor
EGOT eosinophil granule ontogeny transcript (non-protein coding)
EGR2 early growth response 2
EHBP1L1 EH domain binding protein 1-like 1
EHF ets homologous factor
EIF4A2 eukaryotic translation initiation factor 4A2
EIF5A eukaryotic translation initiation factor 5A
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
EML2 echinoderm microtubule associated protein like 2
ENO1 enolase 1, (alpha)
ENO3 enolase 3 (beta, muscle)
ERAL1 Era-like 12S mitochondrial rRNA chaperone 1
ETV3L ets variant 3-like
FAM162A family with sequence similarity 162, member A
FAM178B family with sequence similarity 178, member B
FAM187A family with sequence similarity 187, member A
FAM189A2 family with sequence similarity 189, member A2
FAM65A family with sequence similarity 65, member A
FBRS fibrosin
FCAMR Fc receptor, IgA, IgM, high affinity
FEZF2 FEZ family zinc finger 2
FFAR2 free fatty acid receptor 2
FLJ16124
FLJ31104 uncharacterized LOC441072
FOSL2 FOS-like antigen 2
FOXP4 forkhead box P4
FOXS1 forkhead box S1
FTHL17 ferritin, heavy polypeptide-like 17
FXYD7 FXYD domain containing ion transport regulator 7
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GADD45B growth arrest and DNA-damage-inducible, beta
GATA4 GATA binding protein 4
GDNF-AS1 GDNF antisense RNA 1 (head to head)
GLRA2 glycine receptor, alpha 2
GPBP1 GC-rich promoter binding protein 1
GPC6 glypican 6
GPR171 G protein-coupled receptor 171
GPR21 G protein-coupled receptor 21
GREM1 gremlin 1, DAN family BMP antagonist
GRK5 G protein-coupled receptor kinase 5
HDAC9 histone deacetylase 9
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2
HES1 hes family bHLH transcription factor 1
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
HLA-DMA major histocompatibility complex, class II, DM alpha
HMGB1 high mobility group box 1
HOXA13 homeobox A13
HS1BP3 HCLS1 binding protein 3
ICAM1 intercellular adhesion molecule 1
IFNB1 interferon, beta 1, fibroblast
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IKZF3 IKAROS family zinc finger 3 (Aiolos)
IL13RA1 interleukin 13 receptor, alpha 1
IL1RAPL1 interleukin 1 receptor accessory protein-like 1
IL25 interleukin 25
INADL InaD-like (Drosophila)
IRF8 interferon regulatory factor 8
ITGB8 integrin, beta 8
ITPKC inositol-trisphosphate 3-kinase C
KAT7 K(lysine) acetyltransferase 7
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KDM2A lysine (K)-specific demethylase 2A
KIAA0368 KIAA0368
KIAA1217 KIAA1217
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLF5 Kruppel-like factor 5 (intestinal)
KLHL5 kelch-like family member 5
KMT2A lysine (K)-specific methyltransferase 2A
KREMEN2 kringle containing transmembrane protein 2
KRTAP13-1 keratin associated protein 13-1
KSR1 kinase suppressor of ras 1
L1CAM L1 cell adhesion molecule
LAMP5 lysosomal-associated membrane protein family, member 5
LHX8 LIM homeobox 8
LINC00486 long intergenic non-protein coding RNA 486
LINC00570 long intergenic non-protein coding RNA 570
LINC01549 long intergenic non-protein coding RNA 1549
LOC284648 uncharacterized LOC284648
LOC646626 uncharacterized LOC646626
LOC729683 uncharacterized LOC729683
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LRRC1 leucine rich repeat containing 1
LRRC7 leucine rich repeat containing 7
LTB lymphotoxin beta (TNF superfamily, member 3)
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAMDC2 MAM domain containing 2
MED8 mediator complex subunit 8
METTL1 methyltransferase like 1
MFSD11 major facilitator superfamily domain containing 11
MIR129-2 microRNA 129-2
MIR1538 microRNA 1538
MIR17HG miR-17-92 cluster host gene
MIR1915 microRNA 1915
MIR3935 microRNA 3935
MIR4285 microRNA 4285
MIR4322 microRNA 4322
MIR449C microRNA 449c
MIR4505 microRNA 4505
MIR4513 microRNA 4513
MIR4792 microRNA 4792
MIR4796 microRNA 4796
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MMP9 matrix metallopeptidase 9
MSL1 male-specific lethal 1 homolog (Drosophila)
MSX1 msh homeobox 1
MYB v-myb avian myeloblastosis viral oncogene homolog
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
N4BP3 NEDD4 binding protein 3
NAMA non-protein coding RNA, associated with MAP kinase pathway and growth arrest
NCS1 neuronal calcium sensor 1
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)
NEBL-AS1 NEBL antisense RNA 1
NEK6 NIMA-related kinase 6
NEK8 NIMA-related kinase 8
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NLK nemo-like kinase
NOD2 nucleotide-binding oligomerization domain containing 2
NTNG1 netrin G1
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NUDT14 nudix (nucleoside diphosphate linked moiety X)-type motif 14
OPTN optineurin
ORAI1 ORAI calcium release-activated calcium modulator 1
PACS1 phosphofurin acidic cluster sorting protein 1
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PARK7 parkinson protein 7
PARP8 poly (ADP-ribose) polymerase family, member 8
PAX3 paired box 3
PCDH10 protocadherin 10
PCDH7 protocadherin 7
PCDH9 protocadherin 9
PCSK2 proprotein convertase subtilisin/kexin type 2
PDE4B phosphodiesterase 4B, cAMP-specific
PDZD2 PDZ domain containing 2
PEA15 phosphoprotein enriched in astrocytes 15
PER1 period circadian clock 1
PFN1 profilin 1
PI16 peptidase inhibitor 16
PI3 peptidase inhibitor 3, skin-derived
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PITX2 paired-like homeodomain 2
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
PLS3 plastin 3
PNKD paroxysmal nonkinesigenic dyskinesia
POU2F3 POU class 2 homeobox 3
PPP1R14C protein phosphatase 1, regulatory (inhibitor) subunit 14C
PPP1R16B protein phosphatase 1, regulatory subunit 16B
PPP6C protein phosphatase 6, catalytic subunit
PQBP1 polyglutamine binding protein 1
PRDM12 PR domain containing 12
PRR5L proline rich 5 like
PSD pleckstrin and Sec7 domain containing
PTCH1 patched 1
PTPRR protein tyrosine phosphatase, receptor type, R
RAB10 RAB10, member RAS oncogene family
RAB12 RAB12, member RAS oncogene family
RABGAP1 RAB GTPase activating protein 1
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4
RARA retinoic acid receptor, alpha
RBP5 retinol binding protein 5, cellular
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RELT RELT tumor necrosis factor receptor
RIPK2 receptor-interacting serine-threonine kinase 2
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RYR3 ryanodine receptor 3
SAFB2 scaffold attachment factor B2
SCAF1 SR-related CTD-associated factor 1
SEC24A SEC24 family member A
SEPT11 septin 11
SETD5 SET domain containing 5
SH2B3 SH2B adaptor protein 3
SLC12A8 solute carrier family 12, member 8
SLC30A2 solute carrier family 30 (zinc transporter), member 2
SLC31A2 solute carrier family 31 (copper transporter), member 2
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SMAD3 SMAD family member 3
SMOC1 SPARC related modular calcium binding 1
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SNX27 sorting nexin family member 27
SOCS2 suppressor of cytokine signaling 2
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SOX13 SRY (sex determining region Y)-box 13
SPATS2 spermatogenesis associated, serine-rich 2
ST7 suppression of tumorigenicity 7
STARD8 StAR-related lipid transfer (START) domain containing 8
STX11 syntaxin 11
STX17 syntaxin 17
STX4 syntaxin 4
STXBP5L syntaxin binding protein 5-like
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae)
SUPT4H1 suppressor of Ty 4 homolog 1 (S. cerevisiae)
SYNPO synaptopodin
SYT1 synaptotagmin I
TAMM41 TAM41, mitochondrial translocator assembly and maintenance protein, homolog (S. cerevisiae)
TBC1D17 TBC1 domain family, member 17
TBC1D22B TBC1 domain family, member 22B
TDRD10 tudor domain containing 10
THADA thyroid adenoma associated
TLX1 T-cell leukemia homeobox 1
TM4SF1 transmembrane 4 L six family member 1
TMEM200B transmembrane protein 200B
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8
TNK2 tyrosine kinase, non-receptor, 2
TOM1L1 target of myb1 (chicken)-like 1
TOR3A torsin family 3, member A
TRAF3IP3 TRAF3 interacting protein 3
TRIM13 tripartite motif containing 13
TRPT1 tRNA phosphotransferase 1
TSC22D4 TSC22 domain family, member 4
TSEN54 TSEN54 tRNA splicing endonuclease subunit
TTC30B tetratricopeptide repeat domain 30B
TUBGCP4 tubulin, gamma complex associated protein 4
UBE2E1 ubiquitin-conjugating enzyme E2E 1
UBL7 ubiquitin-like 7
UCK2 uridine-cytidine kinase 2
UNC13B unc-13 homolog B (C. elegans)
UVRAG UV radiation resistance associated
VANGL2 VANGL planar cell polarity protein 2
VASH2 vasohibin 2
VCAN versican
VIM vimentin
VRTN vertebrae development associated
VWC2L von Willebrand factor C domain containing protein 2-like
ZBTB1 zinc finger and BTB domain containing 1
ZBTB17 zinc finger and BTB domain containing 17
ZBTB39 zinc finger and BTB domain containing 39
ZC3H12A zinc finger CCCH-type containing 12A
ZC3H12C zinc finger CCCH-type containing 12C
ZFP91 ZFP91 zinc finger protein
ZFP91-CNTF ZFP91-CNTF readthrough (NMD candidate)
ZMYND15 zinc finger, MYND-type containing 15
ZNF436-AS1 ZNF436 antisense RNA 1
ZNF609 zinc finger protein 609
ZNRF1 zinc and ring finger 1, E3 ubiquitin protein ligase