ca2+ Gene Set

Dataset Phosphosite Textmining Biological Term Annotations
Category structural or functional annotations
Type biological term
Description carbonic anhydrase II|The protein encoded by this gene is one of several isozymes of carbonic anhydrase, which catalyzes reversible hydration of carbon dioxide. Defects in this enzyme are associated with osteopetrosis and renal tubular acidosis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014] (NCBI Entrez Gene Database, 760)
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Genes

360 proteins co-occuring with the biological term ca2+ in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset.

Symbol Name
ACACA acetyl-CoA carboxylase alpha
ACACB acetyl-CoA carboxylase beta
ADCY3 adenylate cyclase 3
ADCY8 adenylate cyclase 8 (brain)
ADD1 adducin 1 (alpha)
ADD2 adducin 2 (beta)
ADRA2A adrenoceptor alpha 2A
ADRBK1 adrenergic, beta, receptor kinase 1
AHCYL1 adenosylhomocysteinase-like 1
AHR aryl hydrocarbon receptor
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALOX5 arachidonate 5-lipoxygenase
ANXA1 annexin A1
ANXA2 annexin A2
ANXA7 annexin A7
AQP5 aquaporin 5
ARPP21 cAMP-regulated phosphoprotein, 21kDa
ASIC1 acid sensing (proton gated) ion channel 1
ATF1 activating transcription factor 1
ATF2 activating transcription factor 2
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide
BAD BCL2-associated agonist of cell death
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide
BCL10 B-cell CLL/lymphoma 10
BRSK1 BR serine/threonine kinase 1
BTK Bruton agammaglobulinemia tyrosine kinase
C1R complement component 1, r subcomponent
C2CD5 C2 calcium-dependent domain containing 5
C3AR1 complement component 3a receptor 1
C5AR2 complement component 5a receptor 2
CABP1 calcium binding protein 1
CABP4 calcium binding protein 4
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CACNB2 calcium channel, voltage-dependent, beta 2 subunit
CACNG2 calcium channel, voltage-dependent, gamma subunit 2
CADPS Ca++-dependent secretion activator
CALD1 caldesmon 1
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CAMK1 calcium/calmodulin-dependent protein kinase I
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CAMK2D calcium/calmodulin-dependent protein kinase II delta
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CAMK4 calcium/calmodulin-dependent protein kinase IV
CAMKK1 calcium/calmodulin-dependent protein kinase kinase 1, alpha
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CANX calnexin
CASQ1 calsequestrin 1 (fast-twitch, skeletal muscle)
CASQ2 calsequestrin 2 (cardiac muscle)
CASR calcium-sensing receptor
CAV1 caveolin 1, caveolae protein, 22kDa
CCR2 chemokine (C-C motif) receptor 2
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD3G CD3g molecule, gamma (CD3-TCR complex)
CD44 CD44 molecule (Indian blood group)
CD6 CD6 molecule
CDC25C cell division cycle 25C
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDK1 cyclin-dependent kinase 1
CDK2 cyclin-dependent kinase 2
CDK5 cyclin-dependent kinase 5
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CDK9 cyclin-dependent kinase 9
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CFL1 cofilin 1 (non-muscle)
CHRM4 cholinergic receptor, muscarinic 4
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
CLCN3 chloride channel, voltage-sensitive 3
CPEB1 cytoplasmic polyadenylation element binding protein 1
CREB1 cAMP responsive element binding protein 1
CREM cAMP responsive element modulator
CRTC1 CREB regulated transcription coactivator 1
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
CSNK1E casein kinase 1, epsilon
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTTN cortactin
CUL5 cullin 5
CXCR2 chemokine (C-X-C motif) receptor 2
CYSLTR1 cysteinyl leukotriene receptor 1
DAPK1 death-associated protein kinase 1
DGKA diacylglycerol kinase, alpha 80kDa
DGKG diacylglycerol kinase, gamma 90kDa
DLG1 discs, large homolog 1 (Drosophila)
DLG4 discs, large homolog 4 (Drosophila)
DLGAP1 discs, large (Drosophila) homolog-associated protein 1
DLX3 distal-less homeobox 3
DNM1 dynamin 1
DNM1L dynamin 1-like
DPYSL2 dihydropyrimidinase-like 2
DRD3 dopamine receptor D3
DSTN destrin (actin depolymerizing factor)
EEF2 eukaryotic translation elongation factor 2
EEF2K eukaryotic elongation factor 2 kinase
EGFR epidermal growth factor receptor
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3
EIF6 eukaryotic translation initiation factor 6
ELK1 ELK1, member of ETS oncogene family
ENPP3 ectonucleotide pyrophosphatase/phosphodiesterase 3
EP300 E1A binding protein p300
ERBB2 erb-b2 receptor tyrosine kinase 2
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
ETV1 ets variant 1
EWSR1 EWS RNA-binding protein 1
EZR ezrin
F9 coagulation factor IX
FBXO43 F-box protein 43
FGFR1 fibroblast growth factor receptor 1
FLNA filamin A, alpha
FLT1 fms-related tyrosine kinase 1
FOXO3 forkhead box O3
FXYD1 FXYD domain containing ion transport regulator 1
FYN FYN proto-oncogene, Src family tyrosine kinase
G6PD glucose-6-phosphate dehydrogenase
GAB1 GRB2-associated binding protein 1
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2
GHR growth hormone receptor
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GJA1 gap junction protein, alpha 1, 43kDa
GJB1 gap junction protein, beta 1, 32kDa
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
GPHN gephyrin
GPM6A glycoprotein M6A
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRIA2 glutamate receptor, ionotropic, AMPA 2
GRIA4 glutamate receptor, ionotropic, AMPA 4
GRIK5 glutamate receptor, ionotropic, kainate 5
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GRK1 G protein-coupled receptor kinase 1
GRK7 G protein-coupled receptor kinase 7
GRM1 glutamate receptor, metabotropic 1
GRM5 glutamate receptor, metabotropic 5
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
H3F3B H3 histone, family 3B (H3.3B)
HCLS1 hematopoietic cell-specific Lyn substrate 1
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HDAC5 histone deacetylase 5
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HNRNPL heterogeneous nuclear ribonucleoprotein L
HSPB6 heat shock protein, alpha-crystallin-related, B6
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase
ILK integrin-linked kinase
INSR insulin receptor
IQGAP1 IQ motif containing GTPase activating protein 1
IRAK1 interleukin-1 receptor-associated kinase 1
IRS1 insulin receptor substrate 1
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
JAK2 Janus kinase 2
JPH2 junctophilin 2
JUN jun proto-oncogene
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2
KCNA4 potassium channel, voltage gated shaker related subfamily A, member 4
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNIP3 Kv channel interacting protein 3, calsenilin
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11
KCNK10 potassium channel, two pore domain subfamily K, member 10
KCNK18 potassium channel, two pore domain subfamily K, member 18
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KCNQ4 potassium channel, voltage gated KQT-like subfamily Q, member 4
KDR kinase insert domain receptor
KRAS Kirsten rat sarcoma viral oncogene homolog
KSR2 kinase suppressor of ras 2
LAT linker for activation of T cells
LCK LCK proto-oncogene, Src family tyrosine kinase
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
LIME1 Lck interacting transmembrane adaptor 1
LIPE lipase, hormone-sensitive
LMTK1 lemur tail kinase 1
LRP4 low density lipoprotein receptor-related protein 4
LRRC7 leucine rich repeat containing 7
MAP2K1 mitogen-activated protein kinase kinase 1
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MAPT microtubule-associated protein tau
MARCKS myristoylated alanine-rich protein kinase C substrate
MBP myelin basic protein
MCM3 minichromosome maintenance complex component 3
MCU mitochondrial calcium uniporter
MELK maternal embryonic leucine zipper kinase
MET MET proto-oncogene, receptor tyrosine kinase
MSN moesin
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYBPC3 myosin binding protein C, cardiac
MYL12B myosin, light chain 12B, regulatory
MYL2 myosin, light chain 2, regulatory, cardiac, slow
MYL7 myosin, light chain 7, regulatory
MYL9 myosin, light chain 9, regulatory
MYLK myosin light chain kinase
MYLK2 myosin light chain kinase 2
MYO6 myosin VI
NCOR2 nuclear receptor corepressor 2
NEFL neurofilament, light polypeptide
NEUROD1 neuronal differentiation 1
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NME2 NME/NM23 nucleoside diphosphate kinase 2
NMT1 N-myristoyltransferase 1
NOS1 nitric oxide synthase 1 (neuronal)
NOS3 nitric oxide synthase 3 (endothelial cell)
NPHS1 nephrosis 1, congenital, Finnish type (nephrin)
NSF N-ethylmaleimide-sensitive factor
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NUMB numb homolog (Drosophila)
NUMBL numb homolog (Drosophila)-like
OPRD1 opioid receptor, delta 1
OPRM1 opioid receptor, mu 1
ORAI1 ORAI calcium release-activated calcium modulator 1
PACSIN1 protein kinase C and casein kinase substrate in neurons 1
PDC phosducin
PDE5A phosphodiesterase 5A, cGMP-specific
PDPK1 3-phosphoinositide dependent protein kinase 1
PECAM1 platelet/endothelial cell adhesion molecule 1
PGAP3 post-GPI attachment to proteins 3
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PKD2 polycystic kidney disease 2 (autosomal dominant)
PKLR pyruvate kinase, liver and RBC
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLAU plasminogen activator, urokinase
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLCG1 phospholipase C, gamma 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLN phospholamban
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PPP1R14A protein phosphatase 1, regulatory (inhibitor) subunit 14A
PPP1R14B protein phosphatase 1, regulatory (inhibitor) subunit 14B
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B
PPP1R9B protein phosphatase 1, regulatory subunit 9B
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PRKCD protein kinase C, delta
PRKCI protein kinase C, iota
PRKCZ protein kinase C, zeta
PRKD1 protein kinase D1
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5
PTEN phosphatase and tensin homolog
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN5 protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)
PTPRA protein tyrosine phosphatase, receptor type, A
PXN paxillin
RAG1 recombination activating gene 1
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RB1 retinoblastoma 1
RCAN1 regulator of calcineurin 1
RDX radixin
REM1 RAS (RAD and GEM)-like GTP-binding 1
RGS4 regulator of G-protein signaling 4
RGS5 regulator of G-protein signaling 5
RGS9 regulator of G-protein signaling 9
RHOA ras homolog family member A
RIMS1 regulating synaptic membrane exocytosis 1
RPH3A rabphilin 3A
RPS19 ribosomal protein S19
RPS6 ribosomal protein S6
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RRAD Ras-related associated with diabetes
RSC1A1 regulatory solute carrier protein, family 1, member 1
RYR1 ryanodine receptor 1 (skeletal)
RYR2 ryanodine receptor 2 (cardiac)
S100A11 S100 calcium binding protein A11
S100A9 S100 calcium binding protein A9
SCG5 secretogranin V
SCN5A sodium channel, voltage gated, type V alpha subunit
SF3B1 splicing factor 3b, subunit 1, 155kDa
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SIK2 salt-inducible kinase 2
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SLN sarcolipin
SMAD2 SMAD family member 2
SNAP23 synaptosomal-associated protein, 23kDa
SNAP25 synaptosomal-associated protein, 25kDa
SNPH syntaphilin
SPHK1 sphingosine kinase 1
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
SPTAN1 spectrin, alpha, non-erythrocytic 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRF serum response factor (c-fos serum response element-binding transcription factor)
SRI sorcin
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STIM1 stromal interaction molecule 1
STK11 serine/threonine kinase 11
STK38 serine/threonine kinase 38
STMN1 stathmin 1
STX1A syntaxin 1A (brain)
STXBP1 syntaxin binding protein 1
STXBP5 syntaxin binding protein 5 (tomosyn)
SYK spleen tyrosine kinase
SYN1 synapsin I
SYNGAP1 synaptic Ras GTPase activating protein 1
SYT1 synaptotagmin I
SYT12 synaptotagmin XII
SYT2 synaptotagmin II
SYT4 synaptotagmin IV
TBC1D4 TBC1 domain family, member 4
TBXA2R thromboxane A2 receptor
TH tyrosine hydroxylase
TNNI3 troponin I type 3 (cardiac)
TNNT2 troponin T type 2 (cardiac)
TOP2A topoisomerase (DNA) II alpha 170kDa
TPD52 tumor protein D52
TPM1 tropomyosin 1 (alpha)
TRPC3 transient receptor potential cation channel, subfamily C, member 3
TRPC4 transient receptor potential cation channel, subfamily C, member 4
TRPC6 transient receptor potential cation channel, subfamily C, member 6
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TRPM7 transient receptor potential cation channel, subfamily M, member 7
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TRPV4 transient receptor potential cation channel, subfamily V, member 4
TRPV5 transient receptor potential cation channel, subfamily V, member 5
TRPV6 transient receptor potential cation channel, subfamily V, member 6
VASP vasodilator-stimulated phosphoprotein
VAV1 vav 1 guanine nucleotide exchange factor
VIM vimentin
WASF1 WAS protein family, member 1
WEE2 WEE1 homolog 2 (S. pombe)
WNK1 WNK lysine deficient protein kinase 1
WNK4 WNK lysine deficient protein kinase 4
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa