caffeic acid-6753 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the caffeic acid-6753 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADCY9 adenylate cyclase 9
AFF2 AF4/FMR2 family, member 2
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ATF7IP activating transcription factor 7 interacting protein
BEX1 brain expressed, X-linked 1
BMP8B bone morphogenetic protein 8b
C2CD2L C2CD2-like
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CALD1 caldesmon 1
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CD33 CD33 molecule
CD58 CD58 molecule
CEND1 cell cycle exit and neuronal differentiation 1
CFH complement factor H
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
COL14A1 collagen, type XIV, alpha 1
COL5A1 collagen, type V, alpha 1
CTNS cystinosin, lysosomal cystine transporter
DAPK3 death-associated protein kinase 3
DCHS2 dachsous cadherin-related 2
DGCR5 DiGeorge syndrome critical region gene 5 (non-protein coding)
DHODH dihydroorotate dehydrogenase (quinone)
DHRS7 dehydrogenase/reductase (SDR family) member 7
DPF3 D4, zinc and double PHD fingers, family 3
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
EFR3B EFR3 homolog B (S. cerevisiae)
ERAP1 endoplasmic reticulum aminopeptidase 1
F10 coagulation factor X
FCAR Fc fragment of IgA receptor
FGA fibrinogen alpha chain
FGF16 fibroblast growth factor 16
FGFR4 fibroblast growth factor receptor 4
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FLOT1 flotillin 1
FOXN2 forkhead box N2
FSCN3 fascin actin-bundling protein 3, testicular
FUS FUS RNA binding protein
GAP43 growth associated protein 43
GATA3 GATA binding protein 3
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GUK1 guanylate kinase 1
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HPS1 Hermansky-Pudlak syndrome 1
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IGFALS insulin-like growth factor binding protein, acid labile subunit
IL11RA interleukin 11 receptor, alpha
INADL InaD-like (Drosophila)
KCNJ13 potassium channel, inwardly rectifying subfamily J, member 13
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
KIAA0226L KIAA0226-like
KRT32 keratin 32, type I
LBP lipopolysaccharide binding protein
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MEF2D myocyte enhancer factor 2D
MST1 macrophage stimulating 1
MX1 MX dynamin-like GTPase 1
NIPSNAP3B nipsnap homolog 3B (C. elegans)
NOTCH4 notch 4
PADI2 peptidyl arginine deiminase, type II
PAOX polyamine oxidase (exo-N4-amino)
PARP11 poly (ADP-ribose) polymerase family, member 11
PARVA parvin, alpha
PAX2 paired box 2
PDGFA platelet-derived growth factor alpha polypeptide
PDK3 pyruvate dehydrogenase kinase, isozyme 3
PHF7 PHD finger protein 7
PHOX2A paired-like homeobox 2a
PMFBP1 polyamine modulated factor 1 binding protein 1
PRIM2 primase, DNA, polypeptide 2 (58kDa)
RET ret proto-oncogene
RIOK3 RIO kinase 3
RPL14 ribosomal protein L14
RPLP2 ribosomal protein, large, P2
RPS11 ribosomal protein S11
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe)
RUNX1 runt-related transcription factor 1
S100A13 S100 calcium binding protein A13
SIGLEC8 sialic acid binding Ig-like lectin 8
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
THBD thrombomodulin
TIMELESS timeless circadian clock
TK2 thymidine kinase 2, mitochondrial
TMEM231 transmembrane protein 231
TMSB15A thymosin beta 15a
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TTLL4 tubulin tyrosine ligase-like family member 4
YIPF4 Yip1 domain family, member 4
ZFP30 ZFP30 zinc finger protein
ZNF117 zinc finger protein 117
ZNF214 zinc finger protein 214
ZNF639 zinc finger protein 639
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
ANKFY1 ankyrin repeat and FYVE domain containing 1
ARRB2 arrestin, beta 2
ATAD5 ATPase family, AAA domain containing 5
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BAHCC1 BAH domain and coiled-coil containing 1
C11ORF63 chromosome 11 open reading frame 63
C17ORF70 chromosome 17 open reading frame 70
CAMKMT calmodulin-lysine N-methyltransferase
CCDC106 coiled-coil domain containing 106
CD3D CD3d molecule, delta (CD3-TCR complex)
CDC37L1 cell division cycle 37-like 1
CEP162 centrosomal protein 162kDa
CHM choroideremia (Rab escort protein 1)
CIDEB cell death-inducing DFFA-like effector b
CLCN6 chloride channel, voltage-sensitive 6
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CPZ carboxypeptidase Z
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
EFNA3 ephrin-A3
EGR2 early growth response 2
EML4 echinoderm microtubule associated protein like 4
EPHA7 EPH receptor A7
ERMAP erythroblast membrane-associated protein (Scianna blood group)
EXOC5 exocyst complex component 5
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FRS2 fibroblast growth factor receptor substrate 2
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GPR39 G protein-coupled receptor 39
GRAMD4 GRAM domain containing 4
GRB7 growth factor receptor-bound protein 7
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GTF2I general transcription factor IIi
HELZ helicase with zinc finger
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HOOK1 hook microtubule-tethering protein 1
HOXC10 homeobox C10
HP1BP3 heterochromatin protein 1, binding protein 3
IFI6 interferon, alpha-inducible protein 6
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IFT140 intraflagellar transport 140
IPO8 importin 8
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KDM8 lysine (K)-specific demethylase 8
KIAA0319L KIAA0319-like
LAMC3 laminin, gamma 3
LIME1 Lck interacting transmembrane adaptor 1
LMO7 LIM domain 7
LNPEP leucyl/cystinyl aminopeptidase
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAP3K7CL MAP3K7 C-terminal like
MBTPS2 membrane-bound transcription factor peptidase, site 2
MOCS3 molybdenum cofactor synthesis 3
NABP1 nucleic acid binding protein 1
NEK11 NIMA-related kinase 11
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
PARM1 prostate androgen-regulated mucin-like protein 1
PCDHA5 protocadherin alpha 5
PDE12 phosphodiesterase 12
PKD2L2 polycystic kidney disease 2-like 2
PLXNA3 plexin A3
POLM polymerase (DNA directed), mu
POMT2 protein-O-mannosyltransferase 2
PRAMEF10 PRAME family member 10
PRB3 proline-rich protein BstNI subfamily 3
PRSS8 protease, serine, 8
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RNF146 ring finger protein 146
RRAGB Ras-related GTP binding B
RUSC2 RUN and SH3 domain containing 2
SCGB2A2 secretoglobin, family 2A, member 2
SCIN scinderin
SCN1B sodium channel, voltage gated, type I beta subunit
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2
SERGEF secretion regulating guanine nucleotide exchange factor
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC22A1 solute carrier family 22 (organic cation transporter), member 1
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SPAG7 sperm associated antigen 7
STARD3 StAR-related lipid transfer (START) domain containing 3
SYTL2 synaptotagmin-like 2
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TBC1D22B TBC1 domain family, member 22B
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TRIM25 tripartite motif containing 25
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
UGT8 UDP glycosyltransferase 8
UNC119 unc-119 homolog (C. elegans)
USP19 ubiquitin specific peptidase 19
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WDR4 WD repeat domain 4
ZNF667 zinc finger protein 667
ZNF675 zinc finger protein 675