cajal body Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A class of nuclear body, first seen after silver staining by Ramon y Cajal in 1903, enriched in small nuclear ribonucleoproteins, and certain general RNA polymerase II transcription factors; ultrastructurally, they appear as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter; involved in aspects of snRNP biogenesis; the protein coilin serves as a marker for Cajal bodies. Some argue that Cajal bodies are the sites for preassembly of transcriptosomes, unitary particles involved in transcription and processing of RNA. (Gene Ontology, GO_0015030)
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Genes

46 proteins localized to the cajal body cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
AK6 adenylate kinase 6 0.663342
PRPF31 pre-mRNA processing factor 31 0.663342
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 0.663342
ISG20 interferon stimulated exonuclease gene 20kDa 0.663342
HINFP histone H4 transcription factor 0.663342
DDX20 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 0.663342
WRAP53 WD repeat containing, antisense to TP53 0.663342
ICE1 interactor of little elongation complex ELL subunit 1 0.663342
XPO1 exportin 1 0.663342
ELL elongation factor RNA polymerase II 0.663342
SMN2 survival of motor neuron 2, centromeric 0.663342
SMN1 survival of motor neuron 1, telomeric 0.663342
ZPR1 ZPR1 zinc finger 0.663342
LSM10 LSM10, U7 small nuclear RNA associated 0.663342
LSG1 large 60S subunit nuclear export GTPase 1 0.663342
CDK2 cyclin-dependent kinase 2 0.663342
ICE2 interactor of little elongation complex ELL subunit 2 0.663342
SNRPC small nuclear ribonucleoprotein polypeptide C 0.663342
NHP2 NHP2 ribonucleoprotein 0.663342
FRG1 FSHD region gene 1 0.663342
USPL1 ubiquitin specific peptidase like 1 0.663342
GEMIN4 gem (nuclear organelle) associated protein 4 0.663342
SRRM2 serine/arginine repetitive matrix 2 0.663342
DKC1 dyskeratosis congenita 1, dyskerin 0.663342
GAR1 GAR1 ribonucleoprotein 0.663342
RDM1 RAD52 motif containing 1 0.663342
EAF1 ELL associated factor 1 0.663342
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B 0.663342
TGS1 trimethylguanosine synthase 1 0.663342
PHAX phosphorylated adaptor for RNA export 0.663342
OIP5 Opa interacting protein 5 0.663342
NPAT nuclear protein, ataxia-telangiectasia locus 0.663342
COIL coilin 0.663342
ZNF473 zinc finger protein 473 0.663342
ZC3H8 zinc finger CCCH-type containing 8 0.663342
SMNDC1 survival motor neuron domain containing 1 0.663342
TRIM22 tripartite motif containing 22 0.663342
NOP58 NOP58 ribonucleoprotein 0.237908
FBLL1 fibrillarin-like 1 0.237908
SART1 squamous cell carcinoma antigen recognized by T cells 0.237908
EFTUD2 elongation factor Tu GTP binding domain containing 2 0.237908
U2AF1 U2 small nuclear RNA auxiliary factor 1 0.237908
PRPF4 pre-mRNA processing factor 4 0.237908
PRPF3 pre-mRNA processing factor 3 0.237908
FBL fibrillarin 0.237908
NOLC1 nucleolar and coiled-body phosphoprotein 1 0.03318