calcium folinate-4725 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the calcium folinate-4725 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM22 ADAM metallopeptidase domain 22
AGFG1 ArfGAP with FG repeats 1
AKR1C4 aldo-keto reductase family 1, member C4
ANP32A-IT1 ANP32A intronic transcript 1
ARL2BP ADP-ribosylation factor-like 2 binding protein
ATM ATM serine/threonine kinase
ATN1 atrophin 1
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BHLHE40 basic helix-loop-helix family, member e40
BST2 bone marrow stromal cell antigen 2
C6 complement component 6
CCDC186 coiled-coil domain containing 186
CEND1 cell cycle exit and neuronal differentiation 1
CEP164 centrosomal protein 164kDa
CHM choroideremia (Rab escort protein 1)
COBLL1 cordon-bleu WH2 repeat protein-like 1
CXCR4 chemokine (C-X-C motif) receptor 4
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
EDNRB endothelin receptor type B
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2
EML2 echinoderm microtubule associated protein like 2
EPB41L5 erythrocyte membrane protein band 4.1 like 5
EXOG endo/exonuclease (5'-3'), endonuclease G-like
FCF1 FCF1 rRNA-processing protein
FDPS farnesyl diphosphate synthase
FLOT1 flotillin 1
GDAP1 ganglioside induced differentiation associated protein 1
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GPATCH4 G patch domain containing 4
GTPBP1 GTP binding protein 1
GULP1 GULP, engulfment adaptor PTB domain containing 1
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4
HFE hemochromatosis
HIST1H2BC histone cluster 1, H2bc
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IL11 interleukin 11
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KITLG KIT ligand
KLF6 Kruppel-like factor 6
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial)
LRP12 low density lipoprotein receptor-related protein 12
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MED18 mediator complex subunit 18
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
NBL1 neuroblastoma 1, DAN family BMP antagonist
NCALD neurocalcin delta
NCOA2 nuclear receptor coactivator 2
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NKTR natural killer cell triggering receptor
NME5 NME/NM23 family member 5
OAZ3 ornithine decarboxylase antizyme 3
OSGIN2 oxidative stress induced growth inhibitor family member 2
PARD6B par-6 family cell polarity regulator beta
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PIGC phosphatidylinositol glycan anchor biosynthesis, class C
PLEKHS1 pleckstrin homology domain containing, family S member 1
PLK4 polo-like kinase 4
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
PTBP3 polypyrimidine tract binding protein 3
PTPN12 protein tyrosine phosphatase, non-receptor type 12
QKI QKI, KH domain containing, RNA binding
RAB30 RAB30, member RAS oncogene family
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
RECQL5 RecQ protein-like 5
RNGTT RNA guanylyltransferase and 5'-phosphatase
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
SCD5 stearoyl-CoA desaturase 5
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SETBP1 SET binding protein 1
SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa
SRD5A3 steroid 5 alpha-reductase 3
SRSF1 serine/arginine-rich splicing factor 1
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2
STK17B serine/threonine kinase 17b
STRN3 striatin, calmodulin binding protein 3
SYNJ2 synaptojanin 2
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TMC6 transmembrane channel-like 6
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae)
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
ZFHX4 zinc finger homeobox 4
ZNF702P zinc finger protein 702, pseudogene
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ACBD4 acyl-CoA binding domain containing 4
ANG angiogenin, ribonuclease, RNase A family, 5
ASAP1-IT1 ASAP1 intronic transcript 1
ATAT1 alpha tubulin acetyltransferase 1
BAHCC1 BAH domain and coiled-coil containing 1
BCL9 B-cell CLL/lymphoma 9
C2ORF27A chromosome 2 open reading frame 27A
C5ORF45 chromosome 5 open reading frame 45
C7ORF69 chromosome 7 open reading frame 69
CD79A CD79a molecule, immunoglobulin-associated alpha
CDON cell adhesion associated, oncogene regulated
CEL carboxyl ester lipase
CLCN6 chloride channel, voltage-sensitive 6
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CNR2 cannabinoid receptor 2 (macrophage)
CRYGC crystallin, gamma C
CSF1R colony stimulating factor 1 receptor
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DNALI1 dynein, axonemal, light intermediate chain 1
DSCAM Down syndrome cell adhesion molecule
DSPP dentin sialophosphoprotein
EYA3 EYA transcriptional coactivator and phosphatase 3
FAM188A family with sequence similarity 188, member A
FGF23 fibroblast growth factor 23
FGF6 fibroblast growth factor 6
FLJ21369 uncharacterized protein FLJ21369
GAMT guanidinoacetate N-methyltransferase
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GNG4 guanine nucleotide binding protein (G protein), gamma 4
HAMP hepcidin antimicrobial peptide
HDAC5 histone deacetylase 5
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
HSPB6 heat shock protein, alpha-crystallin-related, B6
ITGB7 integrin, beta 7
KDM8 lysine (K)-specific demethylase 8
KIAA0754 KIAA0754
KLF3 Kruppel-like factor 3 (basic)
KLHL25 kelch-like family member 25
KREMEN2 kringle containing transmembrane protein 2
KRT15 keratin 15, type I
KRT31 keratin 31, type I
LHX6 LIM homeobox 6
LINC00597 long intergenic non-protein coding RNA 597
LMNB1 lamin B1
LPAR4 lysophosphatidic acid receptor 4
LTC4S leukotriene C4 synthase
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MEP1B meprin A, beta
MFGE8 milk fat globule-EGF factor 8 protein
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MRPL41 mitochondrial ribosomal protein L41
MYLK myosin light chain kinase
N4BP3 NEDD4 binding protein 3
NAG18 NAG18 mRNA
NAT6 N-acetyltransferase 6 (GCN5-related)
NEUROD1 neuronal differentiation 1
NPPB natriuretic peptide B
NPR3 natriuretic peptide receptor 3
NPTX1 neuronal pentraxin I
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PEX26 peroxisomal biogenesis factor 26
PHEX phosphate regulating endopeptidase homolog, X-linked
PHLDA3 pleckstrin homology-like domain, family A, member 3
PLAT plasminogen activator, tissue
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PRR4 proline rich 4 (lacrimal)
RAB36 RAB36, member RAS oncogene family
RAB3A RAB3A, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAPSN receptor-associated protein of the synapse
RECQL4 RecQ protein-like 4
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RIN1 Ras and Rab interactor 1
RNF208 ring finger protein 208
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
SAYSD1 SAYSVFN motif domain containing 1
SKI SKI proto-oncogene
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20
SPINK1 serine peptidase inhibitor, Kazal type 1
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
STEAP4 STEAP family member 4
STX1A syntaxin 1A (brain)
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TCTN2 tectonic family member 2
TDRD12 tudor domain containing 12
THNSL2 threonine synthase-like 2 (S. cerevisiae)
TICAM1 toll-like receptor adaptor molecule 1
TMEM212 transmembrane protein 212
TMEM57 transmembrane protein 57
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
UNC93B1 unc-93 homolog B1 (C. elegans)
ZBTB44 zinc finger and BTB domain containing 44
ZNF37BP zinc finger protein 37B, pseudogene
Funding