calcium ion binding Gene Set

Dataset GO Molecular Function Annotations 2025
Category structural or functional annotations
Type molecular function
Description Interacting selectively and non-covalently with calcium ions (Ca2+). (Gene Ontology, GO_0005509)
External Link http://amigo.geneontology.org/amigo/term/GO:0005509
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Genes

325 genes performing the calcium ion binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.

Symbol Name
ACER3 alkaline ceramidase 3
ADAM8 ADAM metallopeptidase domain 8
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADGRL3 adhesion G protein-coupled receptor L3
ADGRV1 adhesion G protein-coupled receptor V1
AGRN agrin
AIF1 allograft inflammatory factor 1
AIF1L allograft inflammatory factor 1-like
ALOX15B arachidonate 15-lipoxygenase, type B
ALPL alkaline phosphatase, liver/bone/kidney
AMY1A amylase, alpha 1A (salivary)
AMY1B amylase, alpha 1B (salivary)
AMY1C amylase, alpha 1C (salivary)
AMY2A amylase, alpha 2A (pancreatic)
ANXA1 annexin A1
ANXA13 annexin A13
ANXA4 annexin A4
ANXA8L1 annexin A8-like 1
AOAH acyloxyacyl hydrolase (neutrophil)
AOC1 amine oxidase, copper containing 1
AOC3 amine oxidase, copper containing 3
APCS amyloid P component, serum
ARSA arylsulfatase A
ASAH2 N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
ASPH aspartate beta-hydroxylase
ASPN asporin
ASTN2 astrotactin 2
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1
BAIAP3 BAI1-associated protein 3
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BNIP2 BCL2/adenovirus E1B 19kDa interacting protein 2
BRAF B-Raf proto-oncogene, serine/threonine kinase
C1D C1D nuclear receptor corepressor
C1R complement component 1, r subcomponent
C2CD5 C2 calcium-dependent domain containing 5
CABCOCO1 ciliary associated calcium binding coiled-coil 1
CABP4 calcium binding protein 4
CABP5 calcium binding protein 5
CABS1 calcium-binding protein, spermatid-specific 1
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CALB1 calbindin 1, 28kDa
CALB2 calbindin 2
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CALM2 calmodulin 2 (phosphorylase kinase, delta)
CALM3 calmodulin 3 (phosphorylase kinase, delta)
CALML3 calmodulin-like 3
CALML4 calmodulin-like 4
CALML5 calmodulin-like 5
CALML6 calmodulin-like 6
CALR calreticulin
CALR3 calreticulin 3
CALU calumenin
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CANT1 calcium activated nucleotidase 1
CANX calnexin
CAPN1 calpain 1, (mu/I) large subunit
CAPN3 calpain 3, (p94)
CASQ1 calsequestrin 1 (fast-twitch, skeletal muscle)
CASQ2 calsequestrin 2 (cardiac muscle)
CASR calcium-sensing receptor
CCDC47 coiled-coil domain containing 47
CD320 CD320 molecule
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDH24 cadherin 24, type 2
CDHR5 cadherin-related family member 5
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CEMIP2 cell migration inducing hyaluronidase 2
CETN1 centrin, EF-hand protein, 1
CETN2 centrin, EF-hand protein, 2
CETN3 centrin, EF-hand protein, 3
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CHP2 calcineurin-like EF-hand protein 2
CIB1 calcium and integrin binding 1 (calmyrin)
CIB2 calcium and integrin binding family member 2
CIB3 calcium and integrin binding family member 3
CIB4 calcium and integrin binding family member 4
CLEC3B C-type lectin domain family 3, member B
CLEC4A C-type lectin domain family 4, member A
CLEC4E C-type lectin domain family 4, member E
CLEC6A C-type lectin domain family 6, member A
CLXN calaxin
COLEC11 collectin sub-family member 11
COMP cartilage oligomeric matrix protein
COPS2 COP9 signalosome subunit 2
CPNE1 copine I
CPNE6 copine VI (neuronal)
CRACR2A calcium release activated channel regulator 2A
CRNN cornulin
CSRP1 cysteine and glycine-rich protein 1
DHH desert hedgehog
DMTF1 cyclin D binding myb-like transcription factor 1
DNASE1L2 deoxyribonuclease I-like 2
DNASE1L3 deoxyribonuclease I-like 3
DNER delta/notch-like EGF repeat containing
DSC3 desmocollin 3
DSG1 desmoglein 1
DSG2 desmoglein 2
DSG3 desmoglein 3
DSG4 desmoglein 4
DSPP dentin sialophosphoprotein
DUOX2 dual oxidase 2
DYSF dysferlin
EFCAB11 EF-hand calcium binding domain 11
EFCAB9 EF-hand calcium binding domain 9
EFHD1 EF-hand domain family, member D1
EFHD2 EF-hand domain family, member D2
EML1 echinoderm microtubule associated protein like 1
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
ENPP3 ectonucleotide pyrophosphatase/phosphodiesterase 3
ESYT1 extended synaptotagmin-like protein 1
ESYT2 extended synaptotagmin-like protein 2
ESYT3 extended synaptotagmin-like protein 3
F9 coagulation factor IX
FBLN1 fibulin 1
FBN1 fibrillin 1
FER1L5 fer-1-like family member 5
FKBP9 FK506 binding protein 9, 63 kDa
FSCB fibrous sheath CABYR binding protein
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GCA grancalcin, EF-hand calcium binding protein
GJB2 gap junction protein, beta 2, 26kDa
GLCE glucuronic acid epimerase
GPRIN1 G protein regulated inducer of neurite outgrowth 1
GRM7 glutamate receptor, metabotropic 7
GSN gelsolin
GUCA1ANB-GUCA1A GUCA1ANB-GUCA1A readthrough
GUCA1B guanylate cyclase activator 1B (retina)
GUCA1C guanylate cyclase activator 1C
HPCA hippocalcin
HPCAL1 hippocalcin-like 1
HPCAL4 hippocalcin like 4
HPGDS hematopoietic prostaglandin D synthase
HRC histidine rich calcium binding protein
HRNR hornerin
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
IDS iduronate 2-sulfatase
IHH indian hedgehog
IQGAP1 IQ motif containing GTPase activating protein 1
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITIH1 inter-alpha-trypsin inhibitor heavy chain 1
ITLN1 intelectin 1 (galactofuranose binding)
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
ITSN1 intersectin 1 (SH3 domain protein)
KCNIP1 Kv channel interacting protein 1
KCNIP2 Kv channel interacting protein 2
KCNIP3 Kv channel interacting protein 3, calsenilin
KCNIP4 Kv channel interacting protein 4
LETM1 leucine zipper-EF-hand containing transmembrane protein 1
LOXL2 lysyl oxidase-like 2
LPL lipoprotein lipase
LRP2 low density lipoprotein receptor-related protein 2
LTBP4 latent transforming growth factor beta binding protein 4
MAN1B1 mannosidase, alpha, class 1B, member 1
MAN1C1 mannosidase, alpha, class 1C, member 1
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
MCTP1 multiple C2 domains, transmembrane 1
MCTP2 multiple C2 domains, transmembrane 2
MELK maternal embryonic leucine zipper kinase
MEX3B mex-3 RNA binding family member B
MICU1 mitochondrial calcium uptake 1
MICU2 mitochondrial calcium uptake 2
MICU3 mitochondrial calcium uptake family, member 3
MMP1 matrix metallopeptidase 1
MMP12 matrix metallopeptidase 12
MMP13 matrix metallopeptidase 13
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase
MYL10 myosin, light chain 10, regulatory
MYL11 myosin light chain 11
MYL2 myosin, light chain 2, regulatory, cardiac, slow
MYL5 myosin, light chain 5, regulatory
MYL7 myosin, light chain 7, regulatory
MYOF myoferlin
NAALADL1 N-acetylated alpha-linked acidic dipeptidase-like 1
NCALD neurocalcin delta
NCS1 neuronal calcium sensor 1
NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa
NELL2 NEL-like 2 (chicken)
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NOTCH4 notch 4
NRXN1 neurexin 1
NUCB1 nucleobindin 1
NUCB2 nucleobindin 2
OC90 otoconin 90
OCM oncomodulin
OCM2 oncomodulin 2
OTOF otoferlin
OTOL1 otolin 1
PADI1 peptidyl arginine deiminase, type I
PADI4 peptidyl arginine deiminase, type IV
PCDHA4 protocadherin alpha 4
PCDHA7 protocadherin alpha 7
PCDHB6 protocadherin beta 6
PCDHB8 protocadherin beta 8
PCLO piccolo presynaptic cytomatrix protein
PCP4 Purkinje cell protein 4
PDCD6 programmed cell death 6
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PITPNM2 phosphatidylinositol transfer protein, membrane-associated 2
PITPNM3 PITPNM family member 3
PKD2L1 polycystic kidney disease 2-like 1
PLA2G10 phospholipase A2, group X
PLA2G1B phospholipase A2, group IB (pancreas)
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLA2G2C phospholipase A2, group IIC
PLA2G2D phospholipase A2, group IID
PLA2G2E phospholipase A2, group IIE
PLA2G2F phospholipase A2, group IIF
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLA2G4B phospholipase A2, group IVB (cytosolic)
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLA2G4D phospholipase A2, group IVD (cytosolic)
PLA2G4E phospholipase A2, group IVE
PLA2G4F phospholipase A2, group IVF
PLA2G5 phospholipase A2, group V
PLSCR1 phospholipid scramblase 1
PLSCR2 phospholipid scramblase 2
PLSCR3 phospholipid scramblase 3
PLSCR4 phospholipid scramblase 4
PNLIPRP1 pancreatic lipase-related protein 1
PNLIPRP2 pancreatic lipase-related protein 2
PON1 paraoxonase 1
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRKD2 protein kinase D2
PRSS2 protease, serine, 2 (trypsin 2)
PRSS3 protease, serine, 3
PVALB parvalbumin
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated)
RCAN1 regulator of calcineurin 1
RCAN2 regulator of calcineurin 2
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RCN3 reticulocalbin 3, EF-hand calcium binding domain
RCVRN recoverin
REG4 regenerating islet-derived family, member 4
RET ret proto-oncogene
RGN regucalcin
RPH3A rabphilin 3A
RUNX1 runt-related transcription factor 1
RYR1 ryanodine receptor 1 (skeletal)
S100A1 S100 calcium binding protein A1
S100A10 S100 calcium binding protein A10
S100A11 S100 calcium binding protein A11
S100A12 S100 calcium binding protein A12
S100A13 S100 calcium binding protein A13
S100A14 S100 calcium binding protein A14
S100A2 S100 calcium binding protein A2
S100A3 S100 calcium binding protein A3
S100A4 S100 calcium binding protein A4
S100A5 S100 calcium binding protein A5
S100A6 S100 calcium binding protein A6
S100A7 S100 calcium binding protein A7
S100A7A S100 calcium binding protein A7A
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
S100B S100 calcium binding protein B
S100G S100 calcium binding protein G
S100P S100 calcium binding protein P
S100Z S100 calcium binding protein Z
SCGN secretagogin, EF-hand calcium binding protein
SCIN scinderin
SCUBE1 signal peptide, CUB domain, EGF-like 1
SDF4 stromal cell derived factor 4
SELENOP selenoprotein P
SELL selectin L
SHH sonic hedgehog
SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SLIT2 slit homolog 2 (Drosophila)
SLIT3 slit homolog 3 (Drosophila)
SMOC2 SPARC related modular calcium binding 2
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNCB synuclein, beta
SNTN sentan, cilia apical structure protein
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPARCL1 SPARC-like 1 (hevin)
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
SRI sorcin
SRR serine racemase
STIM1 stromal interaction molecule 1
STIM2 stromal interaction molecule 2
SYT10 synaptotagmin X
SYT12 synaptotagmin XII
SYT5 synaptotagmin V
TCHH trichohyalin
TESC tescalcin
TGM2 transglutaminase 2
TGM3 transglutaminase 3
THBS1 thrombospondin 1
THBS3 thrombospondin 3
THBS4 thrombospondin 4
TKT transketolase
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TNNI3 troponin I type 3 (cardiac)
TOX4 TOX high mobility group box family member 4
TPD52 tumor protein D52
TPGS1 tubulin polyglutamylase complex subunit 1
TPM4 tropomyosin 4
TPT1 tumor protein, translationally-controlled 1
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TRPM5 transient receptor potential cation channel, subfamily M, member 5
TTR transthyretin
TTYH2 tweety family member 2
TTYH3 tweety family member 3
TUBB4A tubulin, beta 4A class IVa
VIL1 villin 1
VSNL1 visinin-like 1
ZNF395 zinc finger protein 395