calcium pantothenate-3248 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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194 genes differentially expressed following the calcium pantothenate-3248 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACVR1B activin A receptor, type IB
ADAM19 ADAM metallopeptidase domain 19
AHNAK2 AHNAK nucleoprotein 2
AKAP11 A kinase (PRKA) anchor protein 11
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
ARL4D ADP-ribosylation factor-like 4D
ASPH aspartate beta-hydroxylase
B9D1 B9 protein domain 1
C11ORF63 chromosome 11 open reading frame 63
C3 complement component 3
CDRT1 CMT1A duplicated region transcript 1
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DHRS7 dehydrogenase/reductase (SDR family) member 7
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DUSP10 dual specificity phosphatase 10
ECE1 endothelin converting enzyme 1
EPHB2 EPH receptor B2
EXOC7 exocyst complex component 7
FCF1 FCF1 rRNA-processing protein
FKBP8 FK506 binding protein 8, 38kDa
FLT4 fms-related tyrosine kinase 4
FOSL2 FOS-like antigen 2
FRMD4A FERM domain containing 4A
GK glycerol kinase
GOSR2 golgi SNAP receptor complex member 2
HES2 hes family bHLH transcription factor 2
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HIST1H2BM histone cluster 1, H2bm
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HUS1 HUS1 checkpoint homolog (S. pombe)
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
JUN jun proto-oncogene
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KIAA0319L KIAA0319-like
KREMEN2 kringle containing transmembrane protein 2
LIF leukemia inhibitory factor
LIMCH1 LIM and calponin homology domains 1
LMAN1 lectin, mannose-binding, 1
LMO4 LIM domain only 4
LRP2 low density lipoprotein receptor-related protein 2
LRRC8B leucine rich repeat containing 8 family, member B
MAGEB2 melanoma antigen family B2
MED18 mediator complex subunit 18
MET MET proto-oncogene, receptor tyrosine kinase
MFAP3 microfibrillar-associated protein 3
MFSD11 major facilitator superfamily domain containing 11
MIA3 melanoma inhibitory activity family, member 3
MLANA melan-A
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NCOR2 nuclear receptor corepressor 2
NRF1 nuclear respiratory factor 1
NYNRIN NYN domain and retroviral integrase containing
OSBPL10 oxysterol binding protein-like 10
PCDHB11 protocadherin beta 11
PDE3B phosphodiesterase 3B, cGMP-inhibited
PER1 period circadian clock 1
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PHF3 PHD finger protein 3
PLAU plasminogen activator, urokinase
PLCD1 phospholipase C, delta 1
PLK3 polo-like kinase 3
PML promyelocytic leukemia
PQLC2 PQ loop repeat containing 2
PTPN21 protein tyrosine phosphatase, non-receptor type 21
RHEB Ras homolog enriched in brain
RND1 Rho family GTPase 1
RNF39 ring finger protein 39
RUSC2 RUN and SH3 domain containing 2
S100A6 S100 calcium binding protein A6
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SDS serine dehydratase
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC17A2 solute carrier family 17, member 2
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SMAD1 SMAD family member 1
SNCG synuclein, gamma (breast cancer-specific protein 1)
SOAT2 sterol O-acyltransferase 2
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
STC1 stanniocalcin 1
STON1 stonin 1
STRA6 stimulated by retinoic acid 6
STYK1 serine/threonine/tyrosine kinase 1
SYNGR1 synaptogyrin 1
TBL1Y transducin (beta)-like 1, Y-linked
TCP10 t-complex 10
TMCC2 transmembrane and coiled-coil domain family 2
TMEM57 transmembrane protein 57
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TRIM68 tripartite motif containing 68
TSC22D2 TSC22 domain family, member 2
TSPAN9 tetraspanin 9
UCN urocortin
XDH xanthine dehydrogenase
ZER1 zyg-11 related, cell cycle regulator
ZNF134 zinc finger protein 134

decreased expression

Symbol Name
ABHD14A abhydrolase domain containing 14A
ACAD10 acyl-CoA dehydrogenase family, member 10
ACTG2 actin, gamma 2, smooth muscle, enteric
ACVR2B activin A receptor, type IIB
ADCY7 adenylate cyclase 7
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ATF3 activating transcription factor 3
ATP13A2 ATPase type 13A2
BCL9 B-cell CLL/lymphoma 9
BRPF1 bromodomain and PHD finger containing, 1
C19ORF73 chromosome 19 open reading frame 73
CCNO cyclin O
CDC73 cell division cycle 73
COPS7B COP9 signalosome subunit 7B
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EFHD2 EF-hand domain family, member D2
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
FAM131A family with sequence similarity 131, member A
FAM155B family with sequence similarity 155, member B
FAM184A family with sequence similarity 184, member A
FAM188A family with sequence similarity 188, member A
FAN1 FANCD2/FANCI-associated nuclease 1
FANCC Fanconi anemia, complementation group C
FGD6 FYVE, RhoGEF and PH domain containing 6
FKBP10 FK506 binding protein 10, 65 kDa
FOSL1 FOS-like antigen 1
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FURIN furin (paired basic amino acid cleaving enzyme)
GAREM GRB2 associated, regulator of MAPK1
GPATCH2L G patch domain containing 2-like
GPATCH3 G patch domain containing 3
GRB7 growth factor receptor-bound protein 7
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
GYS1 glycogen synthase 1 (muscle)
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
IFT22 intraflagellar transport 22
IL4R interleukin 4 receptor
ISG15 ISG15 ubiquitin-like modifier
ITPKB inositol-trisphosphate 3-kinase B
KIAA0754 KIAA0754
KRI1 KRI1 homolog (S. cerevisiae)
LMNB1 lamin B1
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LY6D lymphocyte antigen 6 complex, locus D
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MTCL1 microtubule crosslinking factor 1
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit
NARFL nuclear prelamin A recognition factor-like
NIPAL2 NIPA-like domain containing 2
NPTX1 neuronal pentraxin I
NXPH4 neurexophilin 4
P3H1 prolyl 3-hydroxylase 1
PCDHA6 protocadherin alpha 6
PCDHA9 protocadherin alpha 9
PECR peroxisomal trans-2-enoyl-CoA reductase
PGM1 phosphoglucomutase 1
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PLA2G10 phospholipase A2, group X
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
POLH polymerase (DNA directed), eta
POLL polymerase (DNA directed), lambda
PPP6R1 protein phosphatase 6, regulatory subunit 1
PRAMEF11 PRAME family member 11
PRR4 proline rich 4 (lacrimal)
PTPN14 protein tyrosine phosphatase, non-receptor type 14
PTPRU protein tyrosine phosphatase, receptor type, U
QSER1 glutamine and serine rich 1
RNF123 ring finger protein 123
RP2 retinitis pigmentosa 2 (X-linked recessive)
RPAP1 RNA polymerase II associated protein 1
SAMHD1 SAM domain and HD domain 1
SGMS1 sphingomyelin synthase 1
SH3BGR SH3 domain binding glutamate-rich protein
SIX1 SIX homeobox 1
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SPIDR scaffolding protein involved in DNA repair
SSNA1 Sjogren syndrome nuclear autoantigen 1
STAG3 stromal antigen 3
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STX5 syntaxin 5
TCEAL1 transcription elongation factor A (SII)-like 1
TM6SF1 transmembrane 6 superfamily member 1
TMC7 transmembrane channel-like 7
TMEM180 transmembrane protein 180
TMEM209 transmembrane protein 209
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TPCN1 two pore segment channel 1
TPST2 tyrosylprotein sulfotransferase 2
TSPYL2 TSPY-like 2
ZCCHC24 zinc finger, CCHC domain containing 24
ZNF74 zinc finger protein 74
ZNF778 zinc finger protein 778