calycanthine-6221 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the calycanthine-6221 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACBD4 acyl-CoA binding domain containing 4
ACSF2 acyl-CoA synthetase family member 2
ADGRF5 adhesion G protein-coupled receptor F5
AK2 adenylate kinase 2
AKAP8L A kinase (PRKA) anchor protein 8-like
AKR1C1 aldo-keto reductase family 1, member C1
AP1S2 adaptor-related protein complex 1, sigma 2 subunit
ARL1 ADP-ribosylation factor-like 1
ARSB arylsulfatase B
ATG10 autophagy related 10
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BRE brain and reproductive organ-expressed (TNFRSF1A modulator)
C4ORF29 chromosome 4 open reading frame 29
C5AR2 complement component 5a receptor 2
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CAPRIN2 caprin family member 2
CDC25C cell division cycle 25C
CEP68 centrosomal protein 68kDa
CHKB choline kinase beta
DBN1 drebrin 1
EML3 echinoderm microtubule associated protein like 3
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EPB41L2 erythrocyte membrane protein band 4.1-like 2
FBXL18 F-box and leucine-rich repeat protein 18
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GATA1 GATA binding protein 1 (globin transcription factor 1)
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5
GID4 GID complex subunit 4
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GUSBP3 glucuronidase, beta pseudogene 3
HEXA hexosaminidase A (alpha polypeptide)
HOXA4 homeobox A4
IFI6 interferon, alpha-inducible protein 6
INHBA inhibin, beta A
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
ITM2B integral membrane protein 2B
KIAA0040 KIAA0040
KIAA0930 KIAA0930
KLF5 Kruppel-like factor 5 (intestinal)
KLF9 Kruppel-like factor 9
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAPK13 mitogen-activated protein kinase 13
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MAX MYC associated factor X
MCM3AP minichromosome maintenance complex component 3 associated protein
MGC12488
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MICALL1 MICAL-like 1
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MYL5 myosin, light chain 5, regulatory
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NFE2L3 nuclear factor, erythroid 2-like 3
NGLY1 N-glycanase 1
NXPH4 neurexophilin 4
OSMR oncostatin M receptor
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PHLDB1 pleckstrin homology-like domain, family B, member 1
PKD1 polycystic kidney disease 1 (autosomal dominant)
PLTP phospholipid transfer protein
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PMCH pro-melanin-concentrating hormone
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PTGIS prostaglandin I2 (prostacyclin) synthase
R3HCC1L R3H domain and coiled-coil containing 1-like
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RAPSN receptor-associated protein of the synapse
RNF219 ring finger protein 219
RPGR retinitis pigmentosa GTPase regulator
RPL13P5 ribosomal protein L13 pseudogene 5
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SND1-IT1 SND1 intronic transcript 1
STARD3 StAR-related lipid transfer (START) domain containing 3
TAPBP TAP binding protein (tapasin)
TBCD tubulin folding cofactor D
TFPI2 tissue factor pathway inhibitor 2
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast)
TK2 thymidine kinase 2, mitochondrial
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMOD3 tropomodulin 3 (ubiquitous)
TMPRSS2 transmembrane protease, serine 2
TMPRSS3 transmembrane protease, serine 3
TSC22D3 TSC22 domain family, member 3
TYMS thymidylate synthetase
UBE2L3 ubiquitin-conjugating enzyme E2L 3
VARS valyl-tRNA synthetase
VDAC3 voltage-dependent anion channel 3
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae)
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
WDR48 WD repeat domain 48
YY1 YY1 transcription factor
ZBED4 zinc finger, BED-type containing 4
ZBTB43 zinc finger and BTB domain containing 43
ZFPL1 zinc finger protein-like 1
ZNF365 zinc finger protein 365
ZNF419 zinc finger protein 419
ZNF571 zinc finger protein 571

decreased expression

Symbol Name
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3
AHDC1 AT hook, DNA binding motif, containing 1
AKR1C3 aldo-keto reductase family 1, member C3
ANKRD36 ankyrin repeat domain 36
BRAF B-Raf proto-oncogene, serine/threonine kinase
C19ORF24 chromosome 19 open reading frame 24
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CD302 CD302 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CENPT centromere protein T
CFD complement factor D (adipsin)
CHMP7 charged multivesicular body protein 7
CLUH clustered mitochondria (cluA/CLU1) homolog
CNPY3 canopy FGF signaling regulator 3
CUEDC1 CUE domain containing 1
DDIT3 DNA-damage-inducible transcript 3
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
ECHDC3 enoyl CoA hydratase domain containing 3
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
ERCC5 excision repair cross-complementation group 5
EVPL envoplakin
FA2H fatty acid 2-hydroxylase
FBXO22 F-box protein 22
FKBP10 FK506 binding protein 10, 65 kDa
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GPR19 G protein-coupled receptor 19
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HOOK1 hook microtubule-tethering protein 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFLR1 IGF-like family receptor 1
IL17RA interleukin 17 receptor A
JMJD4 jumonji domain containing 4
KAT2A K(lysine) acetyltransferase 2A
KDM5C lysine (K)-specific demethylase 5C
KIAA0895 KIAA0895
KIFAP3 kinesin-associated protein 3
KLHL36 kelch-like family member 36
KLK5 kallikrein-related peptidase 5
LAMB3 laminin, beta 3
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LIG4 ligase IV, DNA, ATP-dependent
LOC730101 uncharacterized LOC730101
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LRP5L low density lipoprotein receptor-related protein 5-like
LRRC49 leucine rich repeat containing 49
MCRS1 microspherule protein 1
MED15 mediator complex subunit 15
MED22 mediator complex subunit 22
MITF microphthalmia-associated transcription factor
MT1H metallothionein 1H
NCAM2 neural cell adhesion molecule 2
NSD1 nuclear receptor binding SET domain protein 1
OLFML3 olfactomedin-like 3
ONECUT2 one cut homeobox 2
PC pyruvate carboxylase
PIBF1 progesterone immunomodulatory binding factor 1
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PTPRU protein tyrosine phosphatase, receptor type, U
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAD54L2 RAD54-like 2 (S. cerevisiae)
RANBP17 RAN binding protein 17
RECQL4 RecQ protein-like 4
RGS19 regulator of G-protein signaling 19
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RNF126P1 ring finger protein 126 pseudogene 1
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SCAMP4 secretory carrier membrane protein 4
SCGB2A2 secretoglobin, family 2A, member 2
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)
SLC12A8 solute carrier family 12, member 8
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC41A3 solute carrier family 41, member 3
SNUPN snurportin 1
SREK1IP1 SREK1-interacting protein 1
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STARD13 StAR-related lipid transfer (START) domain containing 13
TEAD3 TEA domain family member 3
TRAIP TRAF interacting protein
TRAPPC2 trafficking protein particle complex 2
UBXN6 UBX domain protein 6
USP36 ubiquitin specific peptidase 36
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VAV1 vav 1 guanine nucleotide exchange factor
VWA1 von Willebrand factor A domain containing 1
WDR19 WD repeat domain 19
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
ZC3H12A zinc finger CCCH-type containing 12A
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF23 zinc finger protein 23
ZNF268 zinc finger protein 268
ZNF492 zinc finger protein 492
ZNHIT2 zinc finger, HIT-type containing 2