| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the camptothecin-2321 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCF2 | ATP-binding cassette, sub-family F (GCN20), member 2 |
| ADM | adrenomedullin |
| AHNAK | AHNAK nucleoprotein |
| ARC | activity-regulated cytoskeleton-associated protein |
| ATF3 | activating transcription factor 3 |
| BTG2 | BTG family, member 2 |
| CAMK2B | calcium/calmodulin-dependent protein kinase II beta |
| CD300C | CD300c molecule |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| COL7A1 | collagen, type VII, alpha 1 |
| CTGF | connective tissue growth factor |
| CTRL | chymotrypsin-like |
| CTSG | cathepsin G |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DLX2 | distal-less homeobox 2 |
| DUSP1 | dual specificity phosphatase 1 |
| EDN2 | endothelin 2 |
| EGFR | epidermal growth factor receptor |
| EGR1 | early growth response 1 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| FZD1 | frizzled class receptor 1 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GSTA3 | glutathione S-transferase alpha 3 |
| GUCA1A | guanylate cyclase activator 1A (retina) |
| H2AFJ | H2A histone family, member J |
| H3F3B | H3 histone, family 3B (H3.3B) |
| HBEGF | heparin-binding EGF-like growth factor |
| HEXIM1 | hexamethylene bis-acetamide inducible 1 |
| HHAT | hedgehog acyltransferase |
| HIC2 | hypermethylated in cancer 2 |
| HIST1H2AM | histone cluster 1, H2am |
| HIST1H4E | histone cluster 1, H4e |
| HOXA5 | homeobox A5 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
| IER2 | immediate early response 2 |
| IER5 | immediate early response 5 |
| INO80D | INO80 complex subunit D |
| JMJD6 | jumonji domain containing 6 |
| JUN | jun proto-oncogene |
| JUNB | jun B proto-oncogene |
| KMT2A | lysine (K)-specific methyltransferase 2A |
| LIF | leukemia inhibitory factor |
| MADCAM1 | mucosal vascular addressin cell adhesion molecule 1 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAGEA6 | melanoma antigen family A6 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MIR22HG | MIR22 host gene |
| MNMIP1 | manchette microtubule inner protein 1 |
| MSX1 | msh homeobox 1 |
| MT1HL1 | metallothionein 1H-like 1 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NDUFAF5 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 5 |
| NGDN | neuroguidin, EIF4E binding protein |
| NHLH2 | nescient helix loop helix 2 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| OLFML2B | olfactomedin-like 2B |
| OTOR | otoraplin |
| PDCD6 | programmed cell death 6 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PRKAR2A | protein kinase, cAMP-dependent, regulatory, type II, alpha |
| PYHIN1 | pyrin and HIN domain family, member 1 |
| RASL11B | RAS-like, family 11, member B |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 |
| RDH16 | retinol dehydrogenase 16 (all-trans) |
| RGS2 | regulator of G-protein signaling 2 |
| RORA | RAR-related orphan receptor A |
| RPS3A | ribosomal protein S3A |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| RRAD | Ras-related associated with diabetes |
| SAG | S-antigen; retina and pineal gland (arrestin) |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SERPINI2 | serpin peptidase inhibitor, clade I (pancpin), member 2 |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SIX2 | SIX homeobox 2 |
| SLC14A2 | solute carrier family 14 (urea transporter), member 2 |
| SNAI2 | snail family zinc finger 2 |
| SNORA21 | small nucleolar RNA, H/ACA box 21 |
| SOCS1 | suppressor of cytokine signaling 1 |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| SPOCK3 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| TBL2 | transducin (beta)-like 2 |
| TCHH | trichohyalin |
| TLE4 | transducin-like enhancer of split 4 |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TUBB2A | tubulin, beta 2A class IIa |
| ZNF750 | zinc finger protein 750 |
| Symbol | Name |
|---|---|
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase |
| ADNP | activity-dependent neuroprotector homeobox |
| AMD1 | adenosylmethionine decarboxylase 1 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| ARHGAP12 | Rho GTPase activating protein 12 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) |
| ARMC7 | armadillo repeat containing 7 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) |
| BANP | BTG3 associated nuclear protein |
| BRINP3 | bone morphogenetic protein/retinoic acid inducible neural-specific 3 |
| BRIX1 | BRX1, biogenesis of ribosomes |
| C2CD2 | C2 calcium-dependent domain containing 2 |
| CASP8AP2 | caspase 8 associated protein 2 |
| CBLL1 | Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase |
| CDR2 | cerebellar degeneration-related protein 2, 62kDa |
| CHD1 | chromodomain helicase DNA binding protein 1 |
| CLK4 | CDC-like kinase 4 |
| CSTF1 | cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa |
| CTCF | CCCTC-binding factor (zinc finger protein) |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
| DNAAF2 | dynein, axonemal, assembly factor 2 |
| E2F6 | E2F transcription factor 6 |
| EFNA4 | ephrin-A4 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 |
| ERCC6L | excision repair cross-complementation group 6-like |
| FADD | Fas (TNFRSF6)-associated via death domain |
| FBXO34 | F-box protein 34 |
| GPATCH1 | G patch domain containing 1 |
| GRHL2 | grainyhead-like 2 (Drosophila) |
| HAUS3 | HAUS augmin-like complex, subunit 3 |
| HILPDA | hypoxia inducible lipid droplet-associated |
| HJURP | Holliday junction recognition protein |
| IFRD1 | interferon-related developmental regulator 1 |
| ING3 | inhibitor of growth family, member 3 |
| IRS1 | insulin receptor substrate 1 |
| JMJD1C | jumonji domain containing 1C |
| KBTBD2 | kelch repeat and BTB (POZ) domain containing 2 |
| KIAA0922 | KIAA0922 |
| KIF16B | kinesin family member 16B |
| LEMD3 | LEM domain containing 3 |
| MED17 | mediator complex subunit 17 |
| METTL18 | methyltransferase like 18 |
| MGA | MGA, MAX dimerization protein |
| MKL2 | MKL/myocardin-like 2 |
| MSL2 | male-specific lethal 2 homolog (Drosophila) |
| NCK1 | NCK adaptor protein 1 |
| NDC80 | NDC80 kinetochore complex component |
| NFE2L2 | nuclear factor, erythroid 2-like 2 |
| NRBF2 | nuclear receptor binding factor 2 |
| NRIP1 | nuclear receptor interacting protein 1 |
| NUP153 | nucleoporin 153kDa |
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 |
| PPAN | peter pan homolog (Drosophila) |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D |
| PPP1R8 | protein phosphatase 1, regulatory subunit 8 |
| PPRC1 | peroxisome proliferator-activated receptor gamma, coactivator-related 1 |
| PRR15L | proline rich 15-like |
| PTPN3 | protein tyrosine phosphatase, non-receptor type 3 |
| PTRH2 | peptidyl-tRNA hydrolase 2 |
| PUM2 | pumilio RNA-binding family member 2 |
| RANBP6 | RAN binding protein 6 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) |
| RBM15 | RNA binding motif protein 15 |
| RBM7 | RNA binding motif protein 7 |
| RCOR1 | REST corepressor 1 |
| RDH14 | retinol dehydrogenase 14 (all-trans/9-cis/11-cis) |
| RNF111 | ring finger protein 111 |
| RPP38 | ribonuclease P/MRP 38kDa subunit |
| RSBN1 | round spermatid basic protein 1 |
| SCAF8 | SR-related CTD-associated factor 8 |
| SEC24B | SEC24 family member B |
| SETD5 | SET domain containing 5 |
| SETX | senataxin |
| SIRT1 | sirtuin 1 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 |
| SUV420H1 | suppressor of variegation 4-20 homolog 1 (Drosophila) |
| TAF5 | TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa |
| TBK1 | TANK-binding kinase 1 |
| TBPL1 | TBP-like 1 |
| TGS1 | trimethylguanosine synthase 1 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
| TLK2 | tousled-like kinase 2 |
| TNFRSF1A | tumor necrosis factor receptor superfamily, member 1A |
| TRIM32 | tripartite motif containing 32 |
| TRMT12 | tRNA methyltransferase 12 homolog (S. cerevisiae) |
| URB2 | URB2 ribosome biogenesis 2 homolog (S. cerevisiae) |
| WDR5B | WD repeat domain 5B |
| ZBED5 | zinc finger, BED-type containing 5 |
| ZBTB10 | zinc finger and BTB domain containing 10 |
| ZBTB24 | zinc finger and BTB domain containing 24 |
| ZC3H4 | zinc finger CCCH-type containing 4 |
| ZCCHC2 | zinc finger, CCHC domain containing 2 |
| ZHX2 | zinc fingers and homeoboxes 2 |
| ZNF107 | zinc finger protein 107 |
| ZNF143 | zinc finger protein 143 |
| ZNF217 | zinc finger protein 217 |
| ZNF232 | zinc finger protein 232 |
| ZNF267 | zinc finger protein 267 |
| ZNF443 | zinc finger protein 443 |
| ZNHIT6 | zinc finger, HIT-type containing 6 |
