camptothecin-3887 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the camptothecin-3887 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2
ADM adrenomedullin
AMH anti-Mullerian hormone
APOE apolipoprotein E
ARC activity-regulated cytoskeleton-associated protein
ARR3 arrestin 3, retinal (X-arrestin)
ATF3 activating transcription factor 3
BTBD18 BTB (POZ) domain containing 18
BTG2 BTG family, member 2
CBX4 chromobox homolog 4
CD14 CD14 molecule
CDA cytidine deaminase
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEL carboxyl ester lipase
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal)
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
CPNE7 copine VII
CTGF connective tissue growth factor
CXCR4 chemokine (C-X-C motif) receptor 4
CYR61 cysteine-rich, angiogenic inducer, 61
DDIT3 DNA-damage-inducible transcript 3
DDN dendrin
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DLX2 distal-less homeobox 2
DUSP1 dual specificity phosphatase 1
EGR1 early growth response 1
ELN elastin
EN2 engrailed homeobox 2
ENC1 ectodermal-neural cortex 1 (with BTB domain)
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOSL1 FOS-like antigen 1
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
GPR3 G protein-coupled receptor 3
H2AFJ H2A histone family, member J
H3F3B H3 histone, family 3B (H3.3B)
HBEGF heparin-binding EGF-like growth factor
HIST1H3B histone cluster 1, H3b
HYMAI hydatidiform mole associated and imprinted (non-protein coding)
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IER5 immediate early response 5
IL11 interleukin 11
JMJD6 jumonji domain containing 6
JUN jun proto-oncogene
JUNB jun B proto-oncogene
KCNJ14 potassium channel, inwardly rectifying subfamily J, member 14
LEFTY1 left-right determination factor 1
LEFTY2 left-right determination factor 2
LIF leukemia inhibitory factor
LOC157562 uncharacterized LOC157562
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MIR22HG MIR22 host gene
MR1 major histocompatibility complex, class I-related
MSX1 msh homeobox 1
NHLH2 nescient helix loop helix 2
NKX2-5 NK2 homeobox 5
NR4A2 nuclear receptor subfamily 4, group A, member 2
PABPN1 poly(A) binding protein, nuclear 1
PGF placental growth factor
PLK3 polo-like kinase 3
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
POU3F1 POU class 3 homeobox 1
PYGM phosphorylase, glycogen, muscle
RAB33A RAB33A, member RAS oncogene family
RASL11B RAS-like, family 11, member B
RER1 retention in endoplasmic reticulum sorting receptor 1
RFPL3S RFPL3 antisense
RGCC regulator of cell cycle
RGS2 regulator of G-protein signaling 2
RRAD Ras-related associated with diabetes
RSL1D1 ribosomal L1 domain containing 1
RSRP1 arginine/serine-rich protein 1
S100A11 S100 calcium binding protein A11
SAT1 spermidine/spermine N1-acetyltransferase 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SFN stratifin
SGK1 serum/glucocorticoid regulated kinase 1
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SNAI1 snail family zinc finger 1
SOCS1 suppressor of cytokine signaling 1
SOX9 SRY (sex determining region Y)-box 9
TACSTD2 tumor-associated calcium signal transducer 2
TAOK2 TAO kinase 2
TBL2 transducin (beta)-like 2
TBRG4 transforming growth factor beta regulator 4
TLE4 transducin-like enhancer of split 4
UCN urocortin
ZNF750 zinc finger protein 750
ZNF778 zinc finger protein 778

decreased expression

Symbol Name
ACVR1 activin A receptor, type I
ADNP activity-dependent neuroprotector homeobox
AMIGO2 adhesion molecule with Ig-like domain 2
ARHGAP12 Rho GTPase activating protein 12
ARID5B AT rich interactive domain 5B (MRF1-like)
ARL4A ADP-ribosylation factor-like 4A
ARMCX5 armadillo repeat containing, X-linked 5
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
BANP BTG3 associated nuclear protein
BMPR1A bone morphogenetic protein receptor, type IA
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
CDYL chromodomain protein, Y-like
CENPE centromere protein E, 312kDa
CHD1 chromodomain helicase DNA binding protein 1
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CSTF1 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa
CTCF CCCTC-binding factor (zinc finger protein)
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
E2F6 E2F transcription factor 6
EFNA4 ephrin-A4
ELF1 E74-like factor 1 (ets domain transcription factor)
EPHA4 EPH receptor A4
ERCC6L excision repair cross-complementation group 6-like
FAM179B family with sequence similarity 179, member B
FAM60A family with sequence similarity 60, member A
FOXK2 forkhead box K2
GIGYF2 GRB10 interacting GYF protein 2
GIN1 gypsy retrotransposon integrase 1
GOLPH3 golgi phosphoprotein 3 (coat-protein)
GPALPP1 GPALPP motifs containing 1
GRHL2 grainyhead-like 2 (Drosophila)
HJURP Holliday junction recognition protein
IRS1 insulin receptor substrate 1
JARID2 jumonji, AT rich interactive domain 2
KDM3A lysine (K)-specific demethylase 3A
KIAA0232 KIAA0232
KIAA0922 KIAA0922
KIF11 kinesin family member 11
KIF20B kinesin family member 20B
KIN Kin17 DNA and RNA binding protein
LEMD3 LEM domain containing 3
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3
MGA MGA, MAX dimerization protein
MKL2 MKL/myocardin-like 2
MPP5 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
MSL2 male-specific lethal 2 homolog (Drosophila)
NCK1 NCK adaptor protein 1
NDC80 NDC80 kinetochore complex component
NFE2L2 nuclear factor, erythroid 2-like 2
NRIP1 nuclear receptor interacting protein 1
NSUN3 NOP2/Sun domain family, member 3
NUP153 nucleoporin 153kDa
OSBPL11 oxysterol binding protein-like 11
PHF21A PHD finger protein 21A
PIKFYVE phosphoinositide kinase, FYVE finger containing
POLD3 polymerase (DNA-directed), delta 3, accessory subunit
PPAN peter pan homolog (Drosophila)
PPWD1 peptidylprolyl isomerase domain and WD repeat containing 1
PRR15L proline rich 15-like
PUM1 pumilio RNA-binding family member 1
PUM2 pumilio RNA-binding family member 2
QRICH1 glutamine-rich 1
RAPGEF6 Rap guanine nucleotide exchange factor (GEF) 6
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RBM7 RNA binding motif protein 7
RCL1 RNA terminal phosphate cyclase-like 1
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit
RLF rearranged L-myc fusion
RNF111 ring finger protein 111
SCAF8 SR-related CTD-associated factor 8
SEC24B SEC24 family member B
SETD5 SET domain containing 5
SETX senataxin
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
TAF5 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa
TBK1 TANK-binding kinase 1
TGS1 trimethylguanosine synthase 1
TRIM32 tripartite motif containing 32
TRMT12 tRNA methyltransferase 12 homolog (S. cerevisiae)
TROAP trophinin associated protein
TTK TTK protein kinase
USP6NL USP6 N-terminal like
UVRAG UV radiation resistance associated
VANGL1 VANGL planar cell polarity protein 1
WDR44 WD repeat domain 44
ZBED5 zinc finger, BED-type containing 5
ZBTB10 zinc finger and BTB domain containing 10
ZC3H4 zinc finger CCCH-type containing 4
ZCCHC2 zinc finger, CCHC domain containing 2
ZCCHC6 zinc finger, CCHC domain containing 6
ZHX2 zinc fingers and homeoboxes 2
ZNF143 zinc finger protein 143
ZNF443 zinc finger protein 443
ZNF84 zinc finger protein 84
ZNHIT6 zinc finger, HIT-type containing 6
ZZZ3 zinc finger, ZZ-type containing 3