| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
198 genes differentially expressed following the camptothecin-4541 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCF2 | ATP-binding cassette, sub-family F (GCN20), member 2 |
| ADAM23 | ADAM metallopeptidase domain 23 |
| ADM | adrenomedullin |
| ATF3 | activating transcription factor 3 |
| BAMBI | BMP and activin membrane-bound inhibitor |
| BEST2 | bestrophin 2 |
| BTBD18 | BTB (POZ) domain containing 18 |
| BTG2 | BTG family, member 2 |
| CBX4 | chromobox homolog 4 |
| CCDC71 | coiled-coil domain containing 71 |
| CD14 | CD14 molecule |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
| COMMD4 | COMM domain containing 4 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| DLX2 | distal-less homeobox 2 |
| DLX5 | distal-less homeobox 5 |
| EDN1 | endothelin 1 |
| EGR1 | early growth response 1 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) |
| FCF1 | FCF1 rRNA-processing protein |
| FCMR | Fc fragment of IgM receptor |
| FH | fumarate hydratase |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| FOXC1 | forkhead box C1 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GPR3 | G protein-coupled receptor 3 |
| GSTT2 | glutathione S-transferase theta 2 (gene/pseudogene) |
| H2AFJ | H2A histone family, member J |
| HBEGF | heparin-binding EGF-like growth factor |
| HEXIM1 | hexamethylene bis-acetamide inducible 1 |
| HIST1H2AM | histone cluster 1, H2am |
| HIST1H2BG | histone cluster 1, H2bg |
| HIST1H3B | histone cluster 1, H3b |
| HIST1H4E | histone cluster 1, H4e |
| HIST2H2BE | histone cluster 2, H2be |
| HOXA1 | homeobox A1 |
| HOXB2 | homeobox B2 |
| HYAL1 | hyaluronoglucosaminidase 1 |
| HYMAI | hydatidiform mole associated and imprinted (non-protein coding) |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
| IER5 | immediate early response 5 |
| JMJD6 | jumonji domain containing 6 |
| JUN | jun proto-oncogene |
| JUNB | jun B proto-oncogene |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KIF1C | kinesin family member 1C |
| KLF4 | Kruppel-like factor 4 (gut) |
| LEFTY1 | left-right determination factor 1 |
| MADCAM1 | mucosal vascular addressin cell adhesion molecule 1 |
| MAFG | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G |
| MSX1 | msh homeobox 1 |
| NDOR1 | NADPH dependent diflavin oxidoreductase 1 |
| NDUFA5 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NGDN | neuroguidin, EIF4E binding protein |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| OSR2 | odd-skipped related transciption factor 2 |
| PABPN1 | poly(A) binding protein, nuclear 1 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| RAB40A | RAB40A, member RAS oncogene family |
| RASL11B | RAS-like, family 11, member B |
| RDH11 | retinol dehydrogenase 11 (all-trans/9-cis/11-cis) |
| RFPL3S | RFPL3 antisense |
| RHOB | ras homolog family member B |
| RND1 | Rho family GTPase 1 |
| RPS28 | ribosomal protein S28 |
| RRAD | Ras-related associated with diabetes |
| RSRP1 | arginine/serine-rich protein 1 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SIRT4 | sirtuin 4 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SNAI1 | snail family zinc finger 1 |
| SNHG3 | small nucleolar RNA host gene 3 |
| SOCS1 | suppressor of cytokine signaling 1 |
| SRSF5 | serine/arginine-rich splicing factor 5 |
| TBCC | tubulin folding cofactor C |
| TBL2 | transducin (beta)-like 2 |
| TCF3 | transcription factor 3 |
| TLDC1 | TBC/LysM-associated domain containing 1 |
| TLE4 | transducin-like enhancer of split 4 |
| TMEM177 | transmembrane protein 177 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TPP1 | tripeptidyl peptidase I |
| TSPYL2 | TSPY-like 2 |
| TUBB2A | tubulin, beta 2A class IIa |
| UCN | urocortin |
| ULBP2 | UL16 binding protein 2 |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| ZFP36 | ZFP36 ring finger protein |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZNF362 | zinc finger protein 362 |
| ZNF500 | zinc finger protein 500 |
| Symbol | Name |
|---|---|
| ADNP | activity-dependent neuroprotector homeobox |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) |
| ARSJ | arylsulfatase family, member J |
| ASAP1-IT1 | ASAP1 intronic transcript 1 |
| BANP | BTG3 associated nuclear protein |
| BCAR3 | breast cancer anti-estrogen resistance 3 |
| C5ORF30 | chromosome 5 open reading frame 30 |
| CASD1 | CAS1 domain containing 1 |
| CDCA4 | cell division cycle associated 4 |
| CHD1 | chromodomain helicase DNA binding protein 1 |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 |
| CHSY1 | chondroitin sulfate synthase 1 |
| CSTF1 | cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa |
| CTCF | CCCTC-binding factor (zinc finger protein) |
| DUSP11 | dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) |
| DUSP5 | dual specificity phosphatase 5 |
| E2F6 | E2F transcription factor 6 |
| EFNA4 | ephrin-A4 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 |
| FAM60A | family with sequence similarity 60, member A |
| FBXO34 | F-box protein 34 |
| GBX2 | gastrulation brain homeobox 2 |
| GLI3 | GLI family zinc finger 3 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) |
| GRAMD1B | GRAM domain containing 1B |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HJURP | Holliday junction recognition protein |
| HSPBAP1 | HSPB (heat shock 27kDa) associated protein 1 |
| ICE1 | interactor of little elongation complex ELL subunit 1 |
| IRS1 | insulin receptor substrate 1 |
| JMJD1C | jumonji domain containing 1C |
| KAT7 | K(lysine) acetyltransferase 7 |
| KBTBD2 | kelch repeat and BTB (POZ) domain containing 2 |
| KIAA0232 | KIAA0232 |
| KIF18A | kinesin family member 18A |
| KIN | Kin17 DNA and RNA binding protein |
| LEMD3 | LEM domain containing 3 |
| LOC100272216 | uncharacterized LOC100272216 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 |
| MAPK6 | mitogen-activated protein kinase 6 |
| MKL2 | MKL/myocardin-like 2 |
| MTCL1 | microtubule crosslinking factor 1 |
| NAA16 | N(alpha)-acetyltransferase 16, NatA auxiliary subunit |
| NAV2 | neuron navigator 2 |
| NCOA6 | nuclear receptor coactivator 6 |
| NDC80 | NDC80 kinetochore complex component |
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) |
| NFE2L2 | nuclear factor, erythroid 2-like 2 |
| NRIP1 | nuclear receptor interacting protein 1 |
| NUP153 | nucleoporin 153kDa |
| OSBPL11 | oxysterol binding protein-like 11 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 |
| PIAS1 | protein inhibitor of activated STAT, 1 |
| PITPNB | phosphatidylinositol transfer protein, beta |
| POLD3 | polymerase (DNA-directed), delta 3, accessory subunit |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D |
| PUM2 | pumilio RNA-binding family member 2 |
| PVRL3 | poliovirus receptor-related 3 |
| QTRTD1 | queuine tRNA-ribosyltransferase domain containing 1 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 |
| RCOR1 | REST corepressor 1 |
| REV1 | REV1, polymerase (DNA directed) |
| RLF | rearranged L-myc fusion |
| RNF111 | ring finger protein 111 |
| RSBN1 | round spermatid basic protein 1 |
| SAV1 | salvador family WW domain containing protein 1 |
| SCAF8 | SR-related CTD-associated factor 8 |
| SEC24B | SEC24 family member B |
| SETD5 | SET domain containing 5 |
| SGMS1 | sphingomyelin synthase 1 |
| SLC38A2 | solute carrier family 38, member 2 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 |
| SUOX | sulfite oxidase |
| SYBU | syntabulin (syntaxin-interacting) |
| TAF5 | TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa |
| TBC1D31 | TBC1 domain family, member 31 |
| TBCCD1 | TBCC domain containing 1 |
| TBPL1 | TBP-like 1 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
| TNFRSF1A | tumor necrosis factor receptor superfamily, member 1A |
| TRIM24 | tripartite motif containing 24 |
| TRIM32 | tripartite motif containing 32 |
| TRMT12 | tRNA methyltransferase 12 homolog (S. cerevisiae) |
| UBE2O | ubiquitin-conjugating enzyme E2O |
| URB2 | URB2 ribosome biogenesis 2 homolog (S. cerevisiae) |
| VANGL1 | VANGL planar cell polarity protein 1 |
| VEGFC | vascular endothelial growth factor C |
| WDR43 | WD repeat domain 43 |
| WDR47 | WD repeat domain 47 |
| XKR8 | XK, Kell blood group complex subunit-related family, member 8 |
| ZBED5 | zinc finger, BED-type containing 5 |
| ZC3H4 | zinc finger CCCH-type containing 4 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 |
| ZNF189 | zinc finger protein 189 |
| ZNF217 | zinc finger protein 217 |
| ZNF322P1 | zinc finger protein 322 pseudogene 1 |
| ZNF443 | zinc finger protein 443 |
