camptothecin Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A pyranoindolizinoquinoline that has formula C20H16N2O4. (Chemical Entities of Biological Interest Ontology, CHEBI_27656)
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Genes

37 genes co-occuring with the biological term camptothecin in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ATR ATR serine/threonine kinase
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BID BH3 interacting domain death agonist
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CHEK1 checkpoint kinase 1
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CTSB cathepsin B
DIABLO diablo, IAP-binding mitochondrial protein
EGR1 early growth response 1
FOXO1 forkhead box O1
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
IL6 interleukin 6
ISG15 ISG15 ubiquitin-like modifier
MFN2 mitofusin 2
MGMT O-6-methylguanine-DNA methyltransferase
MIR155 microRNA 155
MIR17 microRNA 17
MYC v-myc avian myelocytomatosis viral oncogene homolog
NMI N-myc (and STAT) interactor
PARP1 poly (ADP-ribose) polymerase 1
PLD2 phospholipase D2
POLL polymerase (DNA directed), lambda
PRKCD protein kinase C, delta
RECQL5 RecQ protein-like 5
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
TDP1 tyrosyl-DNA phosphodiesterase 1
THBS1 thrombospondin 1
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TOP1 topoisomerase (DNA) I
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1