canadine-4138 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the canadine-4138 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM20 ADAM metallopeptidase domain 20
AGFG1 ArfGAP with FG repeats 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
AOC3 amine oxidase, copper containing 3
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
BCAT1 branched chain amino-acid transaminase 1, cytosolic
BMP6 bone morphogenetic protein 6
C1ORF95 chromosome 1 open reading frame 95
C21ORF2 chromosome 21 open reading frame 2
C5AR2 complement component 5a receptor 2
CAPZB capping protein (actin filament) muscle Z-line, beta
CD1C CD1c molecule
CD5 CD5 molecule
CD58 CD58 molecule
CLTA clathrin, light chain A
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CYP4A22 cytochrome P450, family 4, subfamily A, polypeptide 22
DAPK3 death-associated protein kinase 3
DCN decorin
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DFNB31 deafness, autosomal recessive 31
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1
DOCK9 dedicator of cytokinesis 9
DRD2 dopamine receptor D2
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
ELAC2 elaC ribonuclease Z 2
ELOVL2 ELOVL fatty acid elongase 2
FASLG Fas ligand (TNF superfamily, member 6)
FLOT1 flotillin 1
FRMD8 FERM domain containing 8
FRMPD1 FERM and PDZ domain containing 1
GFI1 growth factor independent 1 transcription repressor
GLRX glutaredoxin (thioltransferase)
GP2 glycoprotein 2 (zymogen granule membrane)
GPR22 G protein-coupled receptor 22
GSTM5 glutathione S-transferase mu 5
HBEGF heparin-binding EGF-like growth factor
HIF3A hypoxia inducible factor 3, alpha subunit
HIPK2 homeodomain interacting protein kinase 2
HIST1H4E histone cluster 1, H4e
HOXA10 homeobox A10
HOXA11 homeobox A11
HPX hemopexin
HSPG2 heparan sulfate proteoglycan 2
ICA1 islet cell autoantigen 1, 69kDa
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IGLJ3 immunoglobulin lambda joining 3
ING2 inhibitor of growth family, member 2
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KRT6B keratin 6B, type II
LIMCH1 LIM and calponin homology domains 1
MX1 MX dynamin-like GTPase 1
MYCNOS MYCN opposite strand
NF2 neurofibromin 2 (merlin)
NR2E3 nuclear receptor subfamily 2, group E, member 3
NUDCD3 NudC domain containing 3
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OR52A1 olfactory receptor, family 52, subfamily A, member 1
OSGIN2 oxidative stress induced growth inhibitor family member 2
PARG poly (ADP-ribose) glycohydrolase
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PDIA4 protein disulfide isomerase family A, member 4
PDLIM3 PDZ and LIM domain 3
PHLDB1 pleckstrin homology-like domain, family B, member 1
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PRODH2 proline dehydrogenase (oxidase) 2
PRPH2 peripherin 2 (retinal degeneration, slow)
RUNDC3B RUN domain containing 3B
S100A13 S100 calcium binding protein A13
S100A8 S100 calcium binding protein A8
SASH3 SAM and SH3 domain containing 3
SERHL2 serine hydrolase-like 2
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SH3BP2 SH3-domain binding protein 2
SKI SKI proto-oncogene
SLC35E2 solute carrier family 35, member E2
SLC35G2 solute carrier family 35, member G2
SLPI secretory leukocyte peptidase inhibitor
SOCS3 suppressor of cytokine signaling 3
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
STAC SH3 and cysteine rich domain
SZT2 seizure threshold 2 homolog (mouse)
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TBX3 T-box 3
TCF12 transcription factor 12
TDRD12 tudor domain containing 12
TEK TEK tyrosine kinase, endothelial
TEX14 testis expressed 14
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TG thyroglobulin
TMEM212 transmembrane protein 212
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast)
ZNF783 zinc finger family member 783
ZSWIM1 zinc finger, SWIM-type containing 1

decreased expression

Symbol Name
ABI3BP ABI family, member 3 (NESH) binding protein
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ALOX15 arachidonate 15-lipoxygenase
ALPK1 alpha-kinase 1
AMPH amphiphysin
ARPIN actin-related protein 2/3 complex inhibitor
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BCL2A1 BCL2-related protein A1
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
C10ORF95 chromosome 10 open reading frame 95
C11ORF63 chromosome 11 open reading frame 63
C7ORF69 chromosome 7 open reading frame 69
CAMK1 calcium/calmodulin-dependent protein kinase I
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBX8 chromobox homolog 8
CD3D CD3d molecule, delta (CD3-TCR complex)
CD80 CD80 molecule
CDHR2 cadherin-related family member 2
CEL carboxyl ester lipase
CFAP69 cilia and flagella associated protein 69
CSF1R colony stimulating factor 1 receptor
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DBF4B DBF4 zinc finger B
DENND5B DENN/MADD domain containing 5B
ECM1 extracellular matrix protein 1
EPYC epiphycan
ERCC2 excision repair cross-complementation group 2
ERCC4 excision repair cross-complementation group 4
FADS2 fatty acid desaturase 2
FBXL8 F-box and leucine-rich repeat protein 8
FGF22 fibroblast growth factor 22
FRMD1 FERM domain containing 1
GADD45G growth arrest and DNA-damage-inducible, gamma
GINS4 GINS complex subunit 4 (Sld5 homolog)
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GPR157 G protein-coupled receptor 157
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H2BO histone cluster 1, H2bo
HOXD11 homeobox D11
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2
IBSP integrin-binding sialoprotein
IFT140 intraflagellar transport 140
IL17RA interleukin 17 receptor A
IQSEC2 IQ motif and Sec7 domain 2
IRF2BP1 interferon regulatory factor 2 binding protein 1
KIAA0894 KIAA0894 protein
KLF13 Kruppel-like factor 13
LMTK2 lemur tyrosine kinase 2
LOC100131510 uncharacterized LOC100131510
LRRC48 leucine rich repeat containing 48
LTBP2 latent transforming growth factor beta binding protein 2
MST1 macrophage stimulating 1
NNAT neuronatin
NOL12 nucleolar protein 12
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NPR3 natriuretic peptide receptor 3
ONECUT2 one cut homeobox 2
PARP3 poly (ADP-ribose) polymerase family, member 3
PCDHGB6 protocadherin gamma subfamily B, 6
PDE12 phosphodiesterase 12
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PHOX2A paired-like homeobox 2a
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PODXL2 podocalyxin-like 2
POMT2 protein-O-mannosyltransferase 2
PPARG peroxisome proliferator-activated receptor gamma
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PRDM14 PR domain containing 14
PXDC1 PX domain containing 1
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RFXAP regulatory factor X-associated protein
RGS20 regulator of G-protein signaling 20
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RNF126P1 ring finger protein 126 pseudogene 1
RUSC2 RUN and SH3 domain containing 2
SAMD9 sterile alpha motif domain containing 9
SCN10A sodium channel, voltage gated, type X alpha subunit
SLC16A4 solute carrier family 16, member 4
SLMO1 slowmo homolog 1 (Drosophila)
SMR3A submaxillary gland androgen regulated protein 3A
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAGLN3 transgelin 3
TBX19 T-box 19
TEP1 telomerase-associated protein 1
TRIM16 tripartite motif containing 16
UBQLN4 ubiquilin 4
UCN urocortin
VIM vimentin
WFDC2 WAP four-disulfide core domain 2
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZNF423 zinc finger protein 423
ZNF652 zinc finger protein 652
ZNF747 zinc finger protein 747