canavanine-2141 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the canavanine-2141 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ADGRE1 adhesion G protein-coupled receptor E1
ATF7IP activating transcription factor 7 interacting protein
ATG10 autophagy related 10
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BBS4 Bardet-Biedl syndrome 4
C17ORF59 chromosome 17 open reading frame 59
CA5B carbonic anhydrase VB, mitochondrial
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2
CASZ1 castor zinc finger 1
CCDC71 coiled-coil domain containing 71
CCNK cyclin K
CD59 CD59 molecule, complement regulatory protein
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CLCN7 chloride channel, voltage-sensitive 7
CLIC5 chloride intracellular channel 5
COL6A2 collagen, type VI, alpha 2
CPNE7 copine VII
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CSNK1G1 casein kinase 1, gamma 1
DDAH2 dimethylarginine dimethylaminohydrolase 2
DLK2 delta-like 2 homolog (Drosophila)
EXTL3 exostosin-like glycosyltransferase 3
EYA4 EYA transcriptional coactivator and phosphatase 4
FAM65A family with sequence similarity 65, member A
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
GLYAT glycine-N-acyltransferase
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GPR153 G protein-coupled receptor 153
GSN gelsolin
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor
HLA-DRB4 major histocompatibility complex, class II, DR beta 4
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
IDS iduronate 2-sulfatase
IQCK IQ motif containing K
IRF4 interferon regulatory factor 4
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KCTD20 potassium channel tetramerization domain containing 20
KIAA1109 KIAA1109
KIF1A kinesin family member 1A
KIF25 kinesin family member 25
LMF1 lipase maturation factor 1
MAP7 microtubule-associated protein 7
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MARK2 MAP/microtubule affinity-regulating kinase 2
MED25 mediator complex subunit 25
MIP major intrinsic protein of lens fiber
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MLXIPL MLX interacting protein-like
MR1 major histocompatibility complex, class I-related
MST1 macrophage stimulating 1
MYRF myelin regulatory factor
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
NF2 neurofibromin 2 (merlin)
NPY2R neuropeptide Y receptor Y2
NR6A1 nuclear receptor subfamily 6, group A, member 1
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
PDCD2 programmed cell death 2
PDLIM7 PDZ and LIM domain 7 (enigma)
PDZK1 PDZ domain containing 1
PLCL2 phospholipase C-like 2
PRB1 proline-rich protein BstNI subfamily 1
PRKCDBP protein kinase C, delta binding protein
PRKCE protein kinase C, epsilon
PRSS23 protease, serine, 23
PTEN phosphatase and tensin homolog
RAMP1 receptor (G protein-coupled) activity modifying protein 1
SCN11A sodium channel, voltage gated, type XI alpha subunit
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SGPP1 sphingosine-1-phosphate phosphatase 1
SIGLEC8 sialic acid binding Ig-like lectin 8
SIPA1L1 signal-induced proliferation-associated 1 like 1
SIRPB1 signal-regulatory protein beta 1
SLC17A4 solute carrier family 17, member 4
SOCS1 suppressor of cytokine signaling 1
SPIB Spi-B transcription factor (Spi-1/PU.1 related)
SRPX sushi-repeat containing protein, X-linked
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
SYNGR3 synaptogyrin 3
SYTL2 synaptotagmin-like 2
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TBKBP1 TBK1 binding protein 1
TEX15 testis expressed 15
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TMEM132A transmembrane protein 132A
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNK2 tyrosine kinase, non-receptor, 2
TRAF1 TNF receptor-associated factor 1
TRAF4 TNF receptor-associated factor 4
TXK TXK tyrosine kinase
UBE2I ubiquitin-conjugating enzyme E2I
VEGFA vascular endothelial growth factor A
WTAP Wilms tumor 1 associated protein
ZBTB20 zinc finger and BTB domain containing 20
ZC3H7B zinc finger CCCH-type containing 7B
ZFP37 ZFP37 zinc finger protein

decreased expression

Symbol Name
AGBL5 ATP/GTP binding protein-like 5
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
ARG1 arginase 1
ARHGAP10 Rho GTPase activating protein 10
CBX7 chromobox homolog 7
CCDC85C coiled-coil domain containing 85C
CDA cytidine deaminase
CDK3 cyclin-dependent kinase 3
CDKL3 cyclin-dependent kinase-like 3
CGREF1 cell growth regulator with EF-hand domain 1
CHMP6 charged multivesicular body protein 6
CIC capicua transcriptional repressor
CLGN calmegin
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
CNTLN centlein, centrosomal protein
CRELD1 cysteine-rich with EGF-like domains 1
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CTNNBIP1 catenin, beta interacting protein 1
CTSO cathepsin O
DBF4B DBF4 zinc finger B
DDN dendrin
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DENND5B DENN/MADD domain containing 5B
DGKG diacylglycerol kinase, gamma 90kDa
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
E4F1 E4F transcription factor 1
ERN2 endoplasmic reticulum to nucleus signaling 2
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FURIN furin (paired basic amino acid cleaving enzyme)
GJA1 gap junction protein, alpha 1, 43kDa
GMPPB GDP-mannose pyrophosphorylase B
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
GSTA4 glutathione S-transferase alpha 4
GSTT1 glutathione S-transferase theta 1
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIST1H2AJ histone cluster 1, H2aj
HYAL3 hyaluronoglucosaminidase 3
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KIF20A kinesin family member 20A
LINS lines homolog (Drosophila)
LPPR2 lipid phosphate phosphatase-related protein type 2
LPPR3 lipid phosphate phosphatase-related protein type 3
LRP5 low density lipoprotein receptor-related protein 5
LTC4S leukotriene C4 synthase
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAPKBP1 mitogen-activated protein kinase binding protein 1
METTL2B methyltransferase like 2B
MRPL52 mitochondrial ribosomal protein L52
MXD3 MAX dimerization protein 3
MYOZ3 myozenin 3
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NADSYN1 NAD synthetase 1
NINJ2 ninjurin 2
NT5DC3 5'-nucleotidase domain containing 3
OXCT2 3-oxoacid CoA transferase 2
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PADI1 peptidyl arginine deiminase, type I
PCOLCE2 procollagen C-endopeptidase enhancer 2
PEX10 peroxisomal biogenesis factor 10
PEX26 peroxisomal biogenesis factor 26
PHKG2 phosphorylase kinase, gamma 2 (testis)
PNOC prepronociceptin
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRICKLE3 prickle homolog 3 (Drosophila)
QTRT1 queuine tRNA-ribosyltransferase 1
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RAB13 RAB13, member RAS oncogene family
RAB17 RAB17, member RAS oncogene family
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RNF2 ring finger protein 2
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
SLC16A4 solute carrier family 16, member 4
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
SYCP2 synaptonemal complex protein 2
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TCTN1 tectonic family member 1
TEC tec protein tyrosine kinase
TKFC triokinase/FMN cyclase
TMOD3 tropomodulin 3 (ubiquitous)
TRAF2 TNF receptor-associated factor 2
TTC30A tetratricopeptide repeat domain 30A
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UBQLN4 ubiquilin 4
UNC119 unc-119 homolog (C. elegans)
UNC93B1 unc-93 homolog B1 (C. elegans)
WASF3 WAS protein family, member 3
ZBED1 zinc finger, BED-type containing 1
ZC3H12A zinc finger CCCH-type containing 12A
ZMYM3 zinc finger, MYM-type 3
ZNF197 zinc finger protein 197
ZNF212 zinc finger protein 212
ZNF444 zinc finger protein 444
ZNF536 zinc finger protein 536
ZNF623 zinc finger protein 623
ZNF749 zinc finger protein 749