| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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198 genes differentially expressed following the canavanine-2141 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) |
| ADGRE1 | adhesion G protein-coupled receptor E1 |
| ATF7IP | activating transcription factor 7 interacting protein |
| ATG10 | autophagy related 10 |
| ATP12A | ATPase, H+/K+ transporting, nongastric, alpha polypeptide |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| BBS4 | Bardet-Biedl syndrome 4 |
| C17ORF59 | chromosome 17 open reading frame 59 |
| CA5B | carbonic anhydrase VB, mitochondrial |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 |
| CASZ1 | castor zinc finger 1 |
| CCDC71 | coiled-coil domain containing 71 |
| CCNK | cyclin K |
| CD59 | CD59 molecule, complement regulatory protein |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CLIC5 | chloride intracellular channel 5 |
| COL6A2 | collagen, type VI, alpha 2 |
| CPNE7 | copine VII |
| CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like |
| CSNK1G1 | casein kinase 1, gamma 1 |
| DDAH2 | dimethylarginine dimethylaminohydrolase 2 |
| DLK2 | delta-like 2 homolog (Drosophila) |
| EXTL3 | exostosin-like glycosyltransferase 3 |
| EYA4 | EYA transcriptional coactivator and phosphatase 4 |
| FAM65A | family with sequence similarity 65, member A |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 |
| GLYAT | glycine-N-acyltransferase |
| GPLD1 | glycosylphosphatidylinositol specific phospholipase D1 |
| GPR153 | G protein-coupled receptor 153 |
| GSN | gelsolin |
| HIF1AN | hypoxia inducible factor 1, alpha subunit inhibitor |
| HLA-DRB4 | major histocompatibility complex, class II, DR beta 4 |
| HTR4 | 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled |
| IDS | iduronate 2-sulfatase |
| IQCK | IQ motif containing K |
| IRF4 | interferon regulatory factor 4 |
| KCNQ1 | potassium channel, voltage gated KQT-like subfamily Q, member 1 |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| KIAA1109 | KIAA1109 |
| KIF1A | kinesin family member 1A |
| KIF25 | kinesin family member 25 |
| LMF1 | lipase maturation factor 1 |
| MAP7 | microtubule-associated protein 7 |
| MAPK8IP1 | mitogen-activated protein kinase 8 interacting protein 1 |
| MARK2 | MAP/microtubule affinity-regulating kinase 2 |
| MED25 | mediator complex subunit 25 |
| MIP | major intrinsic protein of lens fiber |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MLXIPL | MLX interacting protein-like |
| MR1 | major histocompatibility complex, class I-related |
| MST1 | macrophage stimulating 1 |
| MYRF | myelin regulatory factor |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) |
| NDUFAF5 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 5 |
| NF2 | neurofibromin 2 (merlin) |
| NPY2R | neuropeptide Y receptor Y2 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa |
| PDCD2 | programmed cell death 2 |
| PDLIM7 | PDZ and LIM domain 7 (enigma) |
| PDZK1 | PDZ domain containing 1 |
| PLCL2 | phospholipase C-like 2 |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PRKCDBP | protein kinase C, delta binding protein |
| PRKCE | protein kinase C, epsilon |
| PRSS23 | protease, serine, 23 |
| PTEN | phosphatase and tensin homolog |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 |
| SCN11A | sodium channel, voltage gated, type XI alpha subunit |
| SEC61A2 | Sec61 alpha 2 subunit (S. cerevisiae) |
| SEMA4G | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 |
| SIGLEC8 | sialic acid binding Ig-like lectin 8 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 |
| SIRPB1 | signal-regulatory protein beta 1 |
| SLC17A4 | solute carrier family 17, member 4 |
| SOCS1 | suppressor of cytokine signaling 1 |
| SPIB | Spi-B transcription factor (Spi-1/PU.1 related) |
| SRPX | sushi-repeat containing protein, X-linked |
| ST8SIA3 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 |
| SYNGR3 | synaptogyrin 3 |
| SYTL2 | synaptotagmin-like 2 |
| TAP2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) |
| TBKBP1 | TBK1 binding protein 1 |
| TEX15 | testis expressed 15 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TMEM132A | transmembrane protein 132A |
| TNFRSF13B | tumor necrosis factor receptor superfamily, member 13B |
| TNK2 | tyrosine kinase, non-receptor, 2 |
| TRAF1 | TNF receptor-associated factor 1 |
| TRAF4 | TNF receptor-associated factor 4 |
| TXK | TXK tyrosine kinase |
| UBE2I | ubiquitin-conjugating enzyme E2I |
| VEGFA | vascular endothelial growth factor A |
| WTAP | Wilms tumor 1 associated protein |
| ZBTB20 | zinc finger and BTB domain containing 20 |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZFP37 | ZFP37 zinc finger protein |
| Symbol | Name |
|---|---|
| AGBL5 | ATP/GTP binding protein-like 5 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B |
| ARG1 | arginase 1 |
| ARHGAP10 | Rho GTPase activating protein 10 |
| CBX7 | chromobox homolog 7 |
| CCDC85C | coiled-coil domain containing 85C |
| CDA | cytidine deaminase |
| CDK3 | cyclin-dependent kinase 3 |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CHMP6 | charged multivesicular body protein 6 |
| CIC | capicua transcriptional repressor |
| CLGN | calmegin |
| CLPB | ClpB homolog, mitochondrial AAA ATPase chaperonin |
| CNTLN | centlein, centrosomal protein |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| CTSO | cathepsin O |
| DBF4B | DBF4 zinc finger B |
| DDN | dendrin |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DENND5B | DENN/MADD domain containing 5B |
| DGKG | diacylglycerol kinase, gamma 90kDa |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| E4F1 | E4F transcription factor 1 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| GMPPB | GDP-mannose pyrophosphorylase B |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| GRINA | glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) |
| GSTA4 | glutathione S-transferase alpha 4 |
| GSTT1 | glutathione S-transferase theta 1 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HIST1H2AJ | histone cluster 1, H2aj |
| HYAL3 | hyaluronoglucosaminidase 3 |
| IMPDH1 | IMP (inosine 5'-monophosphate) dehydrogenase 1 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 |
| KIF20A | kinesin family member 20A |
| LINS | lines homolog (Drosophila) |
| LPPR2 | lipid phosphate phosphatase-related protein type 2 |
| LPPR3 | lipid phosphate phosphatase-related protein type 3 |
| LRP5 | low density lipoprotein receptor-related protein 5 |
| LTC4S | leukotriene C4 synthase |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| METTL2B | methyltransferase like 2B |
| MRPL52 | mitochondrial ribosomal protein L52 |
| MXD3 | MAX dimerization protein 3 |
| MYOZ3 | myozenin 3 |
| N4BP2L2-IT2 | N4BPL2 intronic transcript 2 |
| NADSYN1 | NAD synthetase 1 |
| NINJ2 | ninjurin 2 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| OXCT2 | 3-oxoacid CoA transferase 2 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PADI1 | peptidyl arginine deiminase, type I |
| PCOLCE2 | procollagen C-endopeptidase enhancer 2 |
| PEX10 | peroxisomal biogenesis factor 10 |
| PEX26 | peroxisomal biogenesis factor 26 |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) |
| PNOC | prepronociceptin |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RAB11FIP5 | RAB11 family interacting protein 5 (class I) |
| RAB13 | RAB13, member RAS oncogene family |
| RAB17 | RAB17, member RAS oncogene family |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RNF2 | ring finger protein 2 |
| SEMA3G | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G |
| SLC16A4 | solute carrier family 16, member 4 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| SYCP2 | synaptonemal complex protein 2 |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TCTN1 | tectonic family member 1 |
| TEC | tec protein tyrosine kinase |
| TKFC | triokinase/FMN cyclase |
| TMOD3 | tropomodulin 3 (ubiquitous) |
| TRAF2 | TNF receptor-associated factor 2 |
| TTC30A | tetratricopeptide repeat domain 30A |
| UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) |
| UBQLN4 | ubiquilin 4 |
| UNC119 | unc-119 homolog (C. elegans) |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| WASF3 | WAS protein family, member 3 |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZMYM3 | zinc finger, MYM-type 3 |
| ZNF197 | zinc finger protein 197 |
| ZNF212 | zinc finger protein 212 |
| ZNF444 | zinc finger protein 444 |
| ZNF536 | zinc finger protein 536 |
| ZNF623 | zinc finger protein 623 |
| ZNF749 | zinc finger protein 749 |