canavanine-4782 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the canavanine-4782 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACACB acetyl-CoA carboxylase beta
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACBD4 acyl-CoA binding domain containing 4
ACSF2 acyl-CoA synthetase family member 2
ACTG2 actin, gamma 2, smooth muscle, enteric
ANKZF1 ankyrin repeat and zinc finger domain containing 1
AP2S1 adaptor-related protein complex 2, sigma 1 subunit
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
BMP1 bone morphogenetic protein 1
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C1QL1 complement component 1, q subcomponent-like 1
CBX8 chromobox homolog 8
CC2D1A coiled-coil and C2 domain containing 1A
CCL13 chemokine (C-C motif) ligand 13
CDX2 caudal type homeobox 2
CFLAR CASP8 and FADD-like apoptosis regulator
CHKB choline kinase beta
CYTH4 cytohesin 4
DAPK2 death-associated protein kinase 2
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DNPEP aspartyl aminopeptidase
DPF1 D4, zinc and double PHD fingers family 1
DPP4 dipeptidyl-peptidase 4
DPY19L1P1 DPY19L1 pseudogene 1
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
EML3 echinoderm microtubule associated protein like 3
EPB41L1 erythrocyte membrane protein band 4.1-like 1
EPHA1 EPH receptor A1
EPHB2 EPH receptor B2
EPOR erythropoietin receptor
EVA1B eva-1 homolog B (C. elegans)
FAAH fatty acid amide hydrolase
FASTKD2 FAST kinase domains 2
FBXL7 F-box and leucine-rich repeat protein 7
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FGD1 FYVE, RhoGEF and PH domain containing 1
FLJ22184
FSCN1 fascin actin-bundling protein 1
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GJA9 gap junction protein, alpha 9, 59kDa
GJB5 gap junction protein, beta 5, 31.1kDa
GPR153 G protein-coupled receptor 153
GRB10 growth factor receptor-bound protein 10
HBB hemoglobin, beta
HIP1 huntingtin interacting protein 1
HIST1H1B histone cluster 1, H1b
HPCAL4 hippocalcin like 4
HSF1 heat shock transcription factor 1
HSPA12A heat shock 70kDa protein 12A
ICOSLG inducible T-cell co-stimulator ligand
INE1 inactivation escape 1 (non-protein coding)
IQCE IQ motif containing E
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KDM7A lysine (K)-specific demethylase 7A
KDM8 lysine (K)-specific demethylase 8
KRT24 keratin 24, type I
KRT6B keratin 6B, type II
LPCAT4 lysophosphatidylcholine acyltransferase 4
LRP12 low density lipoprotein receptor-related protein 12
MAP2K7 mitogen-activated protein kinase kinase 7
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MEGF6 multiple EGF-like-domains 6
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NBL1 neuroblastoma 1, DAN family BMP antagonist
NR2E3 nuclear receptor subfamily 2, group E, member 3
POU2F2 POU class 2 homeobox 2
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPP4R4 protein phosphatase 4, regulatory subunit 4
PRKG2 protein kinase, cGMP-dependent, type II
PRMT2 protein arginine methyltransferase 2
PTBP3 polypyrimidine tract binding protein 3
RSU1 Ras suppressor protein 1
S100A7 S100 calcium binding protein A7
S100A8 S100 calcium binding protein A8
SEC31B SEC31 homolog B (S. cerevisiae)
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SHOX2 short stature homeobox 2
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1
SMAD6 SMAD family member 6
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
STAC SH3 and cysteine rich domain
STX2 syntaxin 2
SYNGR1 synaptogyrin 1
TEX40 testis expressed 40
THBS3 thrombospondin 3
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TPSAB1 tryptase alpha/beta 1
TTC38 tetratricopeptide repeat domain 38
WDR62 WD repeat domain 62
ZFPL1 zinc finger protein-like 1
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF141 zinc finger protein 141
ZNF286A zinc finger protein 286A
ZNF419 zinc finger protein 419
ZNF646 zinc finger protein 646
ZNF79 zinc finger protein 79

decreased expression

Symbol Name
ABHD3 abhydrolase domain containing 3
ADORA2B adenosine A2b receptor
AIDA axin interactor, dorsalization associated
ALDH18A1 aldehyde dehydrogenase 18 family, member A1
ANKMY2 ankyrin repeat and MYND domain containing 2
ARHGAP12 Rho GTPase activating protein 12
ATAD2B ATPase family, AAA domain containing 2B
AUH AU RNA binding protein/enoyl-CoA hydratase
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BET1 Bet1 golgi vesicular membrane trafficking protein
BRIP1 BRCA1 interacting protein C-terminal helicase 1
CA2 carbonic anhydrase II
CASP8AP2 caspase 8 associated protein 2
CBLL1 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase
CDKN2AIP CDKN2A interacting protein
CEP97 centrosomal protein 97kDa
COMMD10 COMM domain containing 10
CYB5R4 cytochrome b5 reductase 4
DNAAF2 dynein, axonemal, assembly factor 2
DOCK1 dedicator of cytokinesis 1
DPY19L4 dpy-19-like 4 (C. elegans)
DSG2 desmoglein 2
DUS4L dihydrouridine synthase 4-like (S. cerevisiae)
E2F8 E2F transcription factor 8
ERN2 endoplasmic reticulum to nucleus signaling 2
ETNK1 ethanolamine kinase 1
FAM13B family with sequence similarity 13, member B
FAM60A family with sequence similarity 60, member A
FBXO22 F-box protein 22
FLT4 fms-related tyrosine kinase 4
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B
GDE1 glycerophosphodiester phosphodiesterase 1
HIST1H2AI histone cluster 1, H2ai
HRSP12 heat-responsive protein 12
HSPA1L heat shock 70kDa protein 1-like
IL4R interleukin 4 receptor
INSIG2 insulin induced gene 2
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
LRRC8D leucine rich repeat containing 8 family, member D
MAGEF1 melanoma antigen family F1
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3
MAT2B methionine adenosyltransferase II, beta
MED17 mediator complex subunit 17
MIR22HG MIR22 host gene
MRPL39 mitochondrial ribosomal protein L39
MSH2 mutS homolog 2
NAE1 NEDD8 activating enzyme E1 subunit 1
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NEK4 NIMA-related kinase 4
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
NUP62CL nucleoporin 62kDa C-terminal like
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PANX1 pannexin 1
PCMTD2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
PDHX pyruvate dehydrogenase complex, component X
PDZD8 PDZ domain containing 8
PHC1 polyhomeotic homolog 1 (Drosophila)
PIBF1 progesterone immunomodulatory binding factor 1
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
PPIP5K2 diphosphoinositol pentakisphosphate kinase 2
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E
PRDX3 peroxiredoxin 3
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PROCR protein C receptor, endothelial
PTER phosphotriesterase related
RAB8B RAB8B, member RAS oncogene family
RAB9A RAB9A, member RAS oncogene family
RAP1A RAP1A, member of RAS oncogene family
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RNF170 ring finger protein 170
RP2 retinitis pigmentosa 2 (X-linked recessive)
RSBN1 round spermatid basic protein 1
RWDD3 RWD domain containing 3
SACS sacsin molecular chaperone
SEC24B SEC24 family member B
SELT selenoprotein T
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
TASP1 taspase, threonine aspartase, 1
TDRD7 tudor domain containing 7
THAP1 THAP domain containing, apoptosis associated protein 1
TMEM104 transmembrane protein 104
TMEM230 transmembrane protein 230
TRAPPC11 trafficking protein particle complex 11
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
UFSP2 UFM1-specific peptidase 2
YAF2 YY1 associated factor 2
ZBTB10 zinc finger and BTB domain containing 10
ZFP69B ZFP69 zinc finger protein B
ZFYVE16 zinc finger, FYVE domain containing 16
ZNF107 zinc finger protein 107
ZNF184 zinc finger protein 184
ZNF302 zinc finger protein 302
ZNF552 zinc finger protein 552
ZNF571 zinc finger protein 571
ZNF652 zinc finger protein 652
ZNF665 zinc finger protein 665