cancer Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A malignant neoplasm in which new abnormal tissue grow by excessive cellular division and proliferation more rapidly than normal and continues to grow after the stimuli that initiated the new growth cease. (Experimental Factor Ontology, EFO_0000311)
Similar Terms
Downloads & Tools

Genes

30 genes associated with the disease cancer in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ACE angiotensin I converting enzyme
ARL11 ADP-ribosylation factor-like 11
BLM Bloom syndrome, RecQ helicase-like
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
CDKN2A cyclin-dependent kinase inhibitor 2A
CES1 carboxylesterase 1
CES2 carboxylesterase 2
CHEK2 checkpoint kinase 2
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DPYD dihydropyrimidine dehydrogenase
FANCC Fanconi anemia, complementation group C
GSTM1 glutathione S-transferase mu 1
HLA-B major histocompatibility complex, class I, B
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
MMP1 matrix metallopeptidase 1
NQO1 NAD(P)H dehydrogenase, quinone 1
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
TGFBR1 transforming growth factor, beta receptor 1
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)