candidiasis Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description An opportunistic mycosis that involves fungal infection of the mouth, throat, skin, scalp, vagina, fingers, nails, bronchi, lungs, heart and brain by Candida species, of which Candida albicans is the most common. Systemic Candida infections are usually confined to severely immunocompromised persons. (Human Disease Ontology, DOID_1508)
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Genes

274 genes co-occuring with the disease candidiasis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
AIRE autoimmune regulator 2.46059
CD4 CD4 molecule 2.43565
SKAP2 src kinase associated phosphoprotein 2 1.8987
CARD9 caspase recruitment domain family, member 9 1.78894
CA3 carbonic anhydrase III 1.55247
IFNG interferon, gamma 1.4935
ALLC allantoicase 1.39171
ST5 suppression of tumorigenicity 5 1.38909
CNOT8 CCR4-NOT transcription complex, subunit 8 1.30969
SEPT7 septin 7 1.28086
CD79A CD79a molecule, immunoglobulin-associated alpha 1.23646
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 1.22388
STAT1 signal transducer and activator of transcription 1, 91kDa 1.2005
FBXO3 F-box protein 3 1.17421
LTF lactotransferrin 1.12867
NUDT10 nudix (nucleoside diphosphate linked moiety X)-type motif 10 1.12572
TLR2 toll-like receptor 2 1.09041
GDE1 glycerophosphodiester phosphodiesterase 1 1.07278
TM2D2 TM2 domain containing 2 1.07278
MRC1 mannose receptor, C type 1 1.0324
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.01427
RPL10AP3 ribosomal protein L10a pseudogene 3 0.982215
TNF tumor necrosis factor 0.924626
CLEC7A C-type lectin domain family 7, member A 0.894589
IL17A interleukin 17A 0.873281
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.863046
PES1 pescadillo ribosomal biogenesis factor 1 0.849945
DEFB4A defensin, beta 4A 0.847898
MUC7 mucin 7, secreted 0.838066
NUP85 nucleoporin 85kDa 0.833148
IL12RB1 interleukin 12 receptor, beta 1 0.824948
ISYNA1 inositol-3-phosphate synthase 1 0.799103
STATH statherin 0.795411
PGK1 phosphoglycerate kinase 1 0.785984
ALPPL2 alkaline phosphatase, placental-like 2 0.78066
ALPP alkaline phosphatase, placental 0.780251
ALPL alkaline phosphatase, liver/bone/kidney 0.779841
TLR4 toll-like receptor 4 0.761454
B2M beta-2-microglobulin 0.752492
TLR6 toll-like receptor 6 0.727333
MPO myeloperoxidase 0.718039
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 0.714811
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 0.714408
IL4 interleukin 4 0.713601
CLEC4E C-type lectin domain family 4, member E 0.709572
IL2 interleukin 2 0.70233
IL1A interleukin 1, alpha 0.6939
ENO1 enolase 1, (alpha) 0.6939
ALB albumin 0.673518
CST1 cystatin SN 0.672324
S100A8 S100 calcium binding protein A8 0.665166
IL22 interleukin 22 0.6608
RPL10A ribosomal protein L10a 0.635921
IL1B interleukin 1, beta 0.632777
UQCC1 ubiquinol-cytochrome c reductase complex assembly factor 1 0.624143
NADK NAD kinase 0.619051
IL23A interleukin 23, alpha subunit p19 0.598351
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 0.594843
TLR1 toll-like receptor 1 0.590558
IL17F interleukin 17F 0.587444
IARS isoleucyl-tRNA synthetase 0.583941
IL10 interleukin 10 0.582773
IL17RA interleukin 17 receptor A 0.564889
ACSS2 acyl-CoA synthetase short-chain family member 2 0.5645
CLEC4D C-type lectin domain family 4, member D 0.556732
NAGK N-acetylglucosamine kinase 0.551298
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18 0.546644
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 0.543155
SRPX2 sushi-repeat containing protein, X-linked 2 0.541217
SAP18 Sin3A-associated protein, 18kDa 0.537344
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.536957
PFKL phosphofructokinase, liver 0.535796
MBL2 mannose-binding lectin (protein C) 2, soluble 0.532314
LAMP2 lysosomal-associated membrane protein 2 0.529994
CA6 carbonic anhydrase VI 0.522273
DEFA5 defensin, alpha 5, Paneth cell-specific 0.518805
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 0.516879
HTN3 histatin 3 0.513417
RFK riboflavin kinase 0.503824
ORM1 orosomucoid 1 0.503441
PPAN peter pan homolog (Drosophila) 0.503058
FN1 fibronectin 1 0.499614
REG3G regenerating islet-derived 3 gamma 0.478289
S100A9 S100 calcium binding protein A9 0.476772
NLRP10 NLR family, pyrin domain containing 10 0.461639
TRIM37 tripartite motif containing 37 0.460506
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.457109
RPL10 ribosomal protein L10 0.456355
CXCL8 chemokine (C-X-C motif) ligand 8 0.455224
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 0.453716
MUC12 mucin 12, cell surface associated 0.445429
AVPR2 arginine vasopressin receptor 2 0.440914
CDC14A cell division cycle 14A 0.438282
IGLV6-57 immunoglobulin lambda variable 6-57 0.431894
THEM5 thioesterase superfamily member 5 0.430768
TF transferrin 0.430017
AGAP3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 0.428516
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.422515
DOCK8 dedicator of cytokinesis 8 0.421016
TREH trehalase (brush-border membrane glycoprotein) 0.414276
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.406425
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 0.396725
KCNRG potassium channel regulator 0.394491
DUSP12 dual specificity phosphatase 12 0.393374
DUSP8 dual specificity phosphatase 8 0.393001
DCLRE1C DNA cross-link repair 1C 0.391885
NLRP5 NLR family, pyrin domain containing 5 0.384451
TCHH trichohyalin 0.382594
IL6 interleukin 6 0.381852
MAST4 microtubule associated serine/threonine kinase family member 4 0.374068
CD80 CD80 molecule 0.371477
MYD88 myeloid differentiation primary response 88 0.369997
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 0.369628
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae) 0.368149
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease 0.36704
CLEC6A C-type lectin domain family 6, member A 0.365932
DPM1 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit 0.359657
MIR211 microRNA 211 0.357077
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit 0.356341
ADSL adenylosuccinate lyase 0.355235
TPI1 triosephosphate isomerase 1 0.354499
PPP6R2 protein phosphatase 6, regulatory subunit 2 0.353027
PKLR pyruvate kinase, liver and RBC 0.348981
ICAM1 intercellular adhesion molecule 1 0.345308
C5 complement component 5 0.336876
IVD isovaleryl-CoA dehydrogenase 0.335046
EZR ezrin 0.333218
LPO lactoperoxidase 0.328105
CARTPT CART prepropeptide 0.324823
MDH1 malate dehydrogenase 1, NAD (soluble) 0.318635
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase 0.317545
HAX1 HCLS1 associated protein X-1 0.313552
BTNL2 butyrophilin-like 2 0.30631
CD86 CD86 molecule 0.304864
LYZ lysozyme 0.304503
OAF OAF homolog (Drosophila) 0.304503
SEPT5 septin 5 0.304503
PHGDH phosphoglycerate dehydrogenase 0.299812
LSM1 LSM1, U6 small nuclear RNA associated 0.290821
HLA-C major histocompatibility complex, class I, C 0.289744
IGHV3-30 immunoglobulin heavy variable 3-30 0.289386
PKM pyruvate kinase, muscle 0.285802
GNPDA1 glucosamine-6-phosphate deaminase 1 0.285086
DEFB104B defensin, beta 104B 0.284728
DEFA1B defensin, alpha 1B 0.28294
DEFA1 defensin, alpha 1 0.28294
SPAG1 sperm associated antigen 1 0.282582
TECR trans-2,3-enoyl-CoA reductase 0.277584
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit 0.27687
HGS hepatocyte growth factor-regulated tyrosine kinase substrate 0.27687
SYK spleen tyrosine kinase 0.270819
FLNC filamin C, gamma 0.266203
CD99 CD99 molecule 0.264431
LIN7A lin-7 homolog A (C. elegans) 0.261599
INS insulin 0.261245
CCR6 chemokine (C-C motif) receptor 6 0.256299
PPIG peptidylprolyl isomerase G (cyclophilin G) 0.255946
MGAT4C MGAT4 family, member C 0.254888
KLB klotho beta 0.252422
DEFB103A defensin, beta 103A 0.249608
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.247501
LGALS3 lectin, galactoside-binding, soluble, 3 0.243645
ANO7P1 anoctamin 7 pseudogene 1 0.237357
ART3 ADP-ribosyltransferase 3 0.222822
GOT1 glutamic-oxaloacetic transaminase 1, soluble 0.22145
ATP11A ATPase, class VI, type 11A 0.21974
ART1 ADP-ribosyltransferase 1 0.219057
FBP1 fructose-1,6-bisphosphatase 1 0.215653
NLRP3 NLR family, pyrin domain containing 3 0.214975
PNP purine nucleoside phosphorylase 0.214636
DEFB103B defensin, beta 103B 0.213959
IL18 interleukin 18 0.212945
CCL4 chemokine (C-C motif) ligand 4 0.208245
LACTB lactamase, beta 0.204923
FTH1 ferritin, heavy polypeptide 1 0.204593
FTL ferritin, light polypeptide 0.204593
CXXC5 CXXC finger protein 5 0.203604
CTTN cortactin 0.201635
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.200331
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 0.19582
SUMF2 sulfatase modifying factor 2 0.194865
IFNGR1 interferon gamma receptor 1 0.193915
ERAS ES cell expressed Ras 0.193285
LIG4 ligase IV, DNA, ATP-dependent 0.191719
TLR9 toll-like receptor 9 0.188632
PTH parathyroid hormone 0.183541
PLD1 phospholipase D1, phosphatidylcholine-specific 0.182957
SQLE squalene epoxidase 0.180084
PIR pirin (iron-binding nuclear protein) 0.17896
IMPA1 inositol(myo)-1(or 4)-monophosphatase 1 0.177851
EXTL3 exostosin-like glycosyltransferase 3 0.177301
CYTIP cytohesin 1 interacting protein 0.173057
PKP1 plakophilin 1 0.170544
F8 coagulation factor VIII, procoagulant component 0.168854
AJAP1 adherens junctions associated protein 1 0.166768
CD83 CD83 molecule 0.166095
CD3G CD3g molecule, gamma (CD3-TCR complex) 0.162908
TLR7 toll-like receptor 7 0.162707
HAND1 heart and neural crest derivatives expressed 1 0.160948
NLRC4 NLR family, CARD domain containing 4 0.160021
CTSD cathepsin D 0.158778
BID BH3 interacting domain death agonist 0.139405
TACC3 transforming, acidic coiled-coil containing protein 3 0.139063
LY75 lymphocyte antigen 75 0.137334
ALOX15 arachidonate 15-lipoxygenase 0.137296
PIAS1 protein inhibitor of activated STAT, 1 0.136851
BMP2K BMP2 inducible kinase 0.136746
TRIM24 tripartite motif containing 24 0.135883
OR6B2 olfactory receptor, family 6, subfamily B, member 2 0.135755
GPR176 G protein-coupled receptor 176 0.135642
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 0.135238
CYSLTR2 cysteinyl leukotriene receptor 2 0.13474
DYNLT1 dynein, light chain, Tctex-type 1 0.134452
FOXG1 forkhead box G1 0.133939
OR10R2 olfactory receptor, family 10, subfamily R, member 2 0.133777
IL23R interleukin 23 receptor 0.132621
GFI1 growth factor independent 1 transcription repressor 0.131724
KAT8 K(lysine) acetyltransferase 8 0.131519
KRT17 keratin 17, type I 0.13058
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) 0.130254
CPB2 carboxypeptidase B2 (plasma) 0.130221
SH2D3C SH2 domain containing 3C 0.130054
CA1 carbonic anhydrase I 0.129694
PTPN12 protein tyrosine phosphatase, non-receptor type 12 0.128829
MLLT1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 0.128696
OR10K2 olfactory receptor, family 10, subfamily K, member 2 0.128545
PTPRD protein tyrosine phosphatase, receptor type, D 0.128488
TP63 tumor protein p63 0.12841
IL1RN interleukin 1 receptor antagonist 0.12841
F2RL1 coagulation factor II (thrombin) receptor-like 1 0.128391
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 0.127715
IL2RG interleukin 2 receptor, gamma 0.127383
HSH2D hematopoietic SH2 domain containing 0.127342
DSC2 desmocollin 2 0.127109
SIX2 SIX homeobox 2 0.126609
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 0.126497
BCL10 B-cell CLL/lymphoma 10 0.126182
JUP junction plakoglobin 0.125998
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 0.125576
PRB3 proline-rich protein BstNI subfamily 3 0.125576
ADAM17 ADAM metallopeptidase domain 17 0.124798
MALT1 MALT1 paracaspase 0.124238
ADAM10 ADAM metallopeptidase domain 10 0.123495
MED12 mediator complex subunit 12 0.123386
CA4 carbonic anhydrase IV 0.123057
HRH2 histamine receptor H2 0.122232
IL12B interleukin 12B 0.122087
TIA1 TIA1 cytotoxic granule-associated RNA binding protein 0.121971
SI sucrase-isomaltase (alpha-glucosidase) 0.121881
ATRX alpha thalassemia/mental retardation syndrome X-linked 0.121551
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.11972
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae) 0.119621
TGM2 transglutaminase 2 0.119049
CSF3 colony stimulating factor 3 (granulocyte) 0.118775
DEFB1 defensin, beta 1 0.118707
HPN hepsin 0.118392
MYH9 myosin, heavy chain 9, non-muscle 0.11818
MEGF6 multiple EGF-like-domains 6 0.118145
LGALS4 lectin, galactoside-binding, soluble, 4 0.118074
IDO1 indoleamine 2,3-dioxygenase 1 0.117898
DES desmin 0.117242
PRRC2A proline-rich coiled-coil 2A 0.116149
CD24 CD24 molecule 0.115528
LAP3 leucine aminopeptidase 3 0.115007
CBS cystathionine-beta-synthase 0.114315
LCN2 lipocalin 2 0.113861
HBD hemoglobin, delta 0.113649
HK1 hexokinase 1 0.112706
ALOX5 arachidonate 5-lipoxygenase 0.112662
HBA1 hemoglobin, alpha 1 0.112091
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 0.111913
TGFB2 transforming growth factor, beta 2 0.111054
SRCIN1 SRC kinase signaling inhibitor 1 0.109933
HBA2 hemoglobin, alpha 2 0.109407