canrenoic acid-2065 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the canrenoic acid-2065 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ACACA acetyl-CoA carboxylase alpha
ALPP alkaline phosphatase, placental
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
AQR aquarius intron-binding spliceosomal factor
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ARL4D ADP-ribosylation factor-like 4D
ARTN artemin
ATG2A autophagy related 2A
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
BBS9 Bardet-Biedl syndrome 9
BCORL1 BCL6 corepressor-like 1
C10ORF10 chromosome 10 open reading frame 10
C17ORF80 chromosome 17 open reading frame 80
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CADPS2 Ca++-dependent secretion activator 2
CCL20 chemokine (C-C motif) ligand 20
CDADC1 cytidine and dCMP deaminase domain containing 1
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CFAP45 cilia and flagella associated protein 45
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
COL5A1 collagen, type V, alpha 1
CREB3L1 cAMP responsive element binding protein 3-like 1
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CTNS cystinosin, lysosomal cystine transporter
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DDAH2 dimethylarginine dimethylaminohydrolase 2
DTNB dystrobrevin, beta
DUSP2 dual specificity phosphatase 2
EFNA3 ephrin-A3
ELMO2 engulfment and cell motility 2
EPS8L1 EPS8-like 1
EXOC7 exocyst complex component 7
F11R F11 receptor
FCMR Fc fragment of IgM receptor
FGF1 fibroblast growth factor 1 (acidic)
FOXD1 forkhead box D1
FPGS folylpolyglutamate synthase
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GLG1 golgi glycoprotein 1
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GPR137 G protein-coupled receptor 137
HIPK3 homeodomain interacting protein kinase 3
HPS4 Hermansky-Pudlak syndrome 4
ICA1 islet cell autoantigen 1, 69kDa
IGL immunoglobulin lambda locus
IL1RN interleukin 1 receptor antagonist
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8
KRT17 keratin 17, type I
KRT85 keratin 85, type II
LDB1 LIM domain binding 1
LDB3 LIM domain binding 3
LGALS9 lectin, galactoside-binding, soluble, 9
LIG3 ligase III, DNA, ATP-dependent
LINC00339 long intergenic non-protein coding RNA 339
LRP1 low density lipoprotein receptor-related protein 1
LRP6 low density lipoprotein receptor-related protein 6
MAP2K5 mitogen-activated protein kinase kinase 5
MBTD1 mbt domain containing 1
MCCC2 methylcrotonoyl-CoA carboxylase 2 (beta)
MEF2A myocyte enhancer factor 2A
MT1E metallothionein 1E
MYRF myelin regulatory factor
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NADK NAD kinase
OAZ3 ornithine decarboxylase antizyme 3
PACS1 phosphofurin acidic cluster sorting protein 1
PBX1 pre-B-cell leukemia homeobox 1
PLAG1 pleiomorphic adenoma gene 1
PPARD peroxisome proliferator-activated receptor delta
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PPP1R3D protein phosphatase 1, regulatory subunit 3D
RNF126P1 ring finger protein 126 pseudogene 1
RNF39 ring finger protein 39
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SHANK2 SH3 and multiple ankyrin repeat domains 2
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SOD3 superoxide dismutase 3, extracellular
SRCAP Snf2-related CREBBP activator protein
SURF1 surfeit 1
TDRD12 tudor domain containing 12
TFEB transcription factor EB
TKFC triokinase/FMN cyclase
TLN2 talin 2
TOX thymocyte selection-associated high mobility group box
TRIM23 tripartite motif containing 23
TRIM29 tripartite motif containing 29
TTC38 tetratricopeptide repeat domain 38
WDR1 WD repeat domain 1
WDR18 WD repeat domain 18
ZNF137P zinc finger protein 137, pseudogene
ZNF500 zinc finger protein 500
ZNF589 zinc finger protein 589
ZNF787 zinc finger protein 787

decreased expression

Symbol Name
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ANKRD36B ankyrin repeat domain 36B
APLP1 amyloid beta (A4) precursor-like protein 1
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ASB8 ankyrin repeat and SOCS box containing 8
BAK1 BCL2-antagonist/killer 1
C11ORF80 chromosome 11 open reading frame 80
CCDC130 coiled-coil domain containing 130
CD70 CD70 molecule
CEPT1 choline/ethanolamine phosphotransferase 1
CLCN2 chloride channel, voltage-sensitive 2
CLCN5 chloride channel, voltage-sensitive 5
CLIC3 chloride intracellular channel 3
COMMD10 COMM domain containing 10
CST6 cystatin E/M
DCLRE1A DNA cross-link repair 1A
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DNAL4 dynein, axonemal, light chain 4
DPY19L2P2 DPY19L2 pseudogene 2
EAF2 ELL associated factor 2
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3
FAM155A family with sequence similarity 155, member A
FAM169A family with sequence similarity 169, member A
FBXO2 F-box protein 2
FCHSD2 FCH and double SH3 domains 2
GID4 GID complex subunit 4
GLMN glomulin, FKBP associated protein
GPATCH3 G patch domain containing 3
GRB2 growth factor receptor-bound protein 2
H1F0 H1 histone family, member 0
HIPK2 homeodomain interacting protein kinase 2
HIRA histone cell cycle regulator
HOXB13 homeobox B13
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
IK IK cytokine, down-regulator of HLA II
IMPACT impact RWD domain protein
ISOC1 isochorismatase domain containing 1
JMJD4 jumonji domain containing 4
KIAA0894 KIAA0894 protein
KIAA1549L KIAA1549-like
KIFC1 kinesin family member C1
KLHL12 kelch-like family member 12
LGMN legumain
LLGL2 lethal giant larvae homolog 2 (Drosophila)
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAP9 microtubule-associated protein 9
MAVS mitochondrial antiviral signaling protein
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NPM3 nucleophosmin/nucleoplasmin 3
NPY1R neuropeptide Y receptor Y1
NR1D2 nuclear receptor subfamily 1, group D, member 2
OGFRL1 opioid growth factor receptor-like 1
PBLD phenazine biosynthesis-like protein domain containing
PEG3 paternally expressed 3
PEX26 peroxisomal biogenesis factor 26
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PILRB paired immunoglobin-like type 2 receptor beta
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PISD phosphatidylserine decarboxylase
PLA2G15 phospholipase A2, group XV
PTPN9 protein tyrosine phosphatase, non-receptor type 9
RBM41 RNA binding motif protein 41
RPGR retinitis pigmentosa GTPase regulator
SCYL2 SCY1-like 2 (S. cerevisiae)
SECISBP2 SECIS binding protein 2
SEPP1 selenoprotein P, plasma, 1
SESN1 sestrin 1
SFXN1 sideroflexin 1
SIX1 SIX homeobox 1
SLC12A8 solute carrier family 12, member 8
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein
SPATA2L spermatogenesis associated 2-like
SPATA7 spermatogenesis associated 7
SPIN1 spindlin 1
SREK1IP1 SREK1-interacting protein 1
SRSF4 serine/arginine-rich splicing factor 4
STX5 syntaxin 5
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
SYNJ2BP synaptojanin 2 binding protein
THOC1 THO complex 1
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM110 transmembrane protein 110
TMEM260 transmembrane protein 260
UNC119 unc-119 homolog (C. elegans)
WDR19 WD repeat domain 19
WDR91 WD repeat domain 91
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
ZBTB38 zinc finger and BTB domain containing 38
ZDHHC18 zinc finger, DHHC-type containing 18
ZNF281 zinc finger protein 281
ZNF415 zinc finger protein 415
ZNF571 zinc finger protein 571
ZNF665 zinc finger protein 665
ZNF767P zinc finger family member 767, pseudogene
ZNF813 zinc finger protein 813