capsaicin-5673 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the capsaicin-5673 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACO2 aconitase 2, mitochondrial
ADRA1D adrenoceptor alpha 1D
AEBP1 AE binding protein 1
ALPPL2 alkaline phosphatase, placental-like 2
AMACR alpha-methylacyl-CoA racemase
ANP32A-IT1 ANP32A intronic transcript 1
ASB4 ankyrin repeat and SOCS box containing 4
ATF7 activating transcription factor 7
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2
BDNF brain-derived neurotrophic factor
C3 complement component 3
C5AR2 complement component 5a receptor 2
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CD58 CD58 molecule
CFAP69 cilia and flagella associated protein 69
CLTC clathrin, heavy chain (Hc)
CNOT2 CCR4-NOT transcription complex, subunit 2
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DOPEY1 dopey family member 1
DUSP21 dual specificity phosphatase 21
DUSP9 dual specificity phosphatase 9
EDA ectodysplasin A
EFNB3 ephrin-B3
EPHA5 EPH receptor A5
FBXO41 F-box protein 41
GALR3 galanin receptor 3
GFAP glial fibrillary acidic protein
GIMAP6 GTPase, IMAP family member 6
GPR135 G protein-coupled receptor 135
GSN gelsolin
HFE hemochromatosis
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOXB2 homeobox B2
HPX hemopexin
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
IL1R1 interleukin 1 receptor, type I
ING2 inhibitor of growth family, member 2
IRS2 insulin receptor substrate 2
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
JAG1 jagged 1
KIAA1107 KIAA1107
KRTAP1-3 keratin associated protein 1-3
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LDLR low density lipoprotein receptor
LIF leukemia inhibitory factor
LINC00341 long intergenic non-protein coding RNA 341
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1
MAOB monoamine oxidase B
MBD3 methyl-CpG binding domain protein 3
MECOM MDS1 and EVI1 complex locus
MN1 meningioma (disrupted in balanced translocation) 1
MPPE1 metallophosphoesterase 1
MSTN myostatin
MTRF1L mitochondrial translational release factor 1-like
NBL1 neuroblastoma 1, DAN family BMP antagonist
NCF2 neutrophil cytosolic factor 2
NLRP1 NLR family, pyrin domain containing 1
NPHP1 nephronophthisis 1 (juvenile)
OR2B6 olfactory receptor, family 2, subfamily B, member 6
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCBP3 poly(rC) binding protein 3
PCDHB13 protocadherin beta 13
PEX3 peroxisomal biogenesis factor 3
PLCD1 phospholipase C, delta 1
PLK3 polo-like kinase 3
POU1F1 POU class 1 homeobox 1
PRTN3 proteinase 3
PSG11 pregnancy specific beta-1-glycoprotein 11
QKI QKI, KH domain containing, RNA binding
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RB1 retinoblastoma 1
RBM12B RNA binding motif protein 12B
RNF24 ring finger protein 24
RUNX1 runt-related transcription factor 1
SAFB scaffold attachment factor B
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
SH3BP2 SH3-domain binding protein 2
SIGLEC6 sialic acid binding Ig-like lectin 6
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC39A9 solute carrier family 39, member 9
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SPON1 spondin 1, extracellular matrix protein
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3
SSBP1 single-stranded DNA binding protein 1, mitochondrial
TCEAL2 transcription elongation factor A (SII)-like 2
TLE2 transducin-like enhancer of split 2
TRIM68 tripartite motif containing 68
TRPM6 transient receptor potential cation channel, subfamily M, member 6
TSHR thyroid stimulating hormone receptor
UMPS uridine monophosphate synthetase
ZIC3 Zic family member 3
ZNF407 zinc finger protein 407

decreased expression

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ACTL8 actin-like 8
ADGRG2 adhesion G protein-coupled receptor G2
AFAP1 actin filament associated protein 1
AMDHD2 amidohydrolase domain containing 2
ARMCX2 armadillo repeat containing, X-linked 2
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BMP4 bone morphogenetic protein 4
BTF3P12 basic transcription factor 3 pseudogene 12
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C6ORF47 chromosome 6 open reading frame 47
CA11 carbonic anhydrase XI
CCDC121 coiled-coil domain containing 121
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CEMIP cell migration inducing protein, hyaluronan binding
CGREF1 cell growth regulator with EF-hand domain 1
CHKB choline kinase beta
CORT cortistatin
CRIP1 cysteine-rich protein 1 (intestinal)
DGAT1 diacylglycerol O-acyltransferase 1
EDAR ectodysplasin A receptor
ERCC6 excision repair cross-complementation group 6
FAM189A2 family with sequence similarity 189, member A2
FAM198B family with sequence similarity 198, member B
FRAT1 frequently rearranged in advanced T-cell lymphomas 1
FSTL3 follistatin-like 3 (secreted glycoprotein)
GALK1 galactokinase 1
GDAP1 ganglioside induced differentiation associated protein 1
GLS2 glutaminase 2 (liver, mitochondrial)
GSTA4 glutathione S-transferase alpha 4
GSTCD glutathione S-transferase, C-terminal domain containing
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HOXA4 homeobox A4
INO80D INO80 complex subunit D
KIAA0319L KIAA0319-like
LARP6 La ribonucleoprotein domain family, member 6
LHX1 LIM homeobox 1
LIG4 ligase IV, DNA, ATP-dependent
LMNB1 lamin B1
LMO2 LIM domain only 2 (rhombotin-like 1)
LOC100286895 cell division cycle 27 homolog pseudogene
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAP9 microtubule-associated protein 9
MAPK12 mitogen-activated protein kinase 12
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NCS1 neuronal calcium sensor 1
NKX3-2 NK3 homeobox 2
NPFFR1 neuropeptide FF receptor 1
NPM3 nucleophosmin/nucleoplasmin 3
NUP62CL nucleoporin 62kDa C-terminal like
OLFML2A olfactomedin-like 2A
PARP16 poly (ADP-ribose) polymerase family, member 16
PCDHB3 protocadherin beta 3
PDLIM2 PDZ and LIM domain 2 (mystique)
PEX26 peroxisomal biogenesis factor 26
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PODNL1 podocan-like 1
POLH polymerase (DNA directed), eta
PRODH proline dehydrogenase (oxidase) 1
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
R3HCC1L R3H domain and coiled-coil containing 1-like
RECQL4 RecQ protein-like 4
RFTN1 raftlin, lipid raft linker 1
RIBC2 RIB43A domain with coiled-coils 2
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RNF2 ring finger protein 2
RPGRIP1L RPGRIP1-like
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
S100A9 S100 calcium binding protein A9
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SOX12 SRY (sex determining region Y)-box 12
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
SYNC syncoilin, intermediate filament protein
TBR1 T-box, brain, 1
TMC5 transmembrane channel-like 5
TMPRSS3 transmembrane protease, serine 3
TPCN1 two pore segment channel 1
TPRA1 transmembrane protein, adipocyte asscociated 1
TRAIP TRAF interacting protein
TREM1 triggering receptor expressed on myeloid cells 1
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TTC33 tetratricopeptide repeat domain 33
TUBGCP5 tubulin, gamma complex associated protein 5
UBXN6 UBX domain protein 6
USP20 ubiquitin specific peptidase 20
VEZT vezatin, adherens junctions transmembrane protein
ZNF250 zinc finger protein 250
ZNF428 zinc finger protein 428
ZNF516 zinc finger protein 516
ZNF571 zinc finger protein 571
ZNF701 zinc finger protein 701
ZNF747 zinc finger protein 747