| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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194 genes differentially expressed following the captopril-1907 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACLY | ATP citrate lyase |
| AEN | apoptosis enhancing nuclease |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| ASIC1 | acid sensing (proton gated) ion channel 1 |
| C17ORF75 | chromosome 17 open reading frame 75 |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase |
| CCP110 | centriolar coiled coil protein 110kDa |
| CCPG1 | cell cycle progression 1 |
| CD53 | CD53 molecule |
| CDS1 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 |
| CELSR2 | cadherin, EGF LAG seven-pass G-type receptor 2 |
| CHRNA3 | cholinergic receptor, nicotinic, alpha 3 (neuronal) |
| CIAO1 | cytosolic iron-sulfur assembly component 1 |
| CPOX | coproporphyrinogen oxidase |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| DHX8 | DEAH (Asp-Glu-Ala-His) box polypeptide 8 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| E4F1 | E4F transcription factor 1 |
| EGLN2 | egl-9 family hypoxia-inducible factor 2 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM188A | family with sequence similarity 188, member A |
| FAM50B | family with sequence similarity 50, member B |
| FLJ42627 | uncharacterized LOC645644 |
| FOSL2 | FOS-like antigen 2 |
| FSCN1 | fascin actin-bundling protein 1 |
| GJD2 | gap junction protein, delta 2, 36kDa |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O |
| GPN3 | GPN-loop GTPase 3 |
| GPR21 | G protein-coupled receptor 21 |
| GTF2F2 | general transcription factor IIF, polypeptide 2, 30kDa |
| HCFC1 | host cell factor C1 |
| HIST1H3G | histone cluster 1, H3g |
| HSPB6 | heat shock protein, alpha-crystallin-related, B6 |
| IGKV1D-13 | immunoglobulin kappa variable 1D-13 |
| INPP5D | inositol polyphosphate-5-phosphatase, 145kDa |
| IQCK | IQ motif containing K |
| IRGQ | immunity-related GTPase family, Q |
| ITSN1 | intersectin 1 (SH3 domain protein) |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 |
| KCTD15 | potassium channel tetramerization domain containing 15 |
| KLF12 | Kruppel-like factor 12 |
| KPTN | kaptin (actin binding protein) |
| KRBOX4 | KRAB box domain containing 4 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) |
| LETM1 | leucine zipper-EF-hand containing transmembrane protein 1 |
| LPAR2 | lysophosphatidic acid receptor 2 |
| LRIG2 | leucine-rich repeats and immunoglobulin-like domains 2 |
| MAGT1 | magnesium transporter 1 |
| MAPK10 | mitogen-activated protein kinase 10 |
| MICALL2 | MICAL-like 2 |
| MST1 | macrophage stimulating 1 |
| NCSTN | nicastrin |
| NLE1 | notchless homolog 1 (Drosophila) |
| NPAP1 | nuclear pore associated protein 1 |
| NRSN2 | neurensin 2 |
| NUMB | numb homolog (Drosophila) |
| OSBPL10 | oxysterol binding protein-like 10 |
| PATZ1 | POZ (BTB) and AT hook containing zinc finger 1 |
| PELP1 | proline, glutamate and leucine rich protein 1 |
| PLD2 | phospholipase D2 |
| POLR3D | polymerase (RNA) III (DNA directed) polypeptide D, 44kDa |
| PRRC2B | proline-rich coiled-coil 2B |
| PSG9 | pregnancy specific beta-1-glycoprotein 9 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 |
| RARG | retinoic acid receptor, gamma |
| RNF39 | ring finger protein 39 |
| RP2 | retinitis pigmentosa 2 (X-linked recessive) |
| RPRD1A | regulation of nuclear pre-mRNA domain containing 1A |
| RPS3A | ribosomal protein S3A |
| SAMHD1 | SAM domain and HD domain 1 |
| SEC23A | Sec23 homolog A (S. cerevisiae) |
| SEC23B | Sec23 homolog B (S. cerevisiae) |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C |
| SFTPB | surfactant protein B |
| SLC17A9 | solute carrier family 17 (vesicular nucleotide transporter), member 9 |
| SLC25A16 | solute carrier family 25 (mitochondrial carrier), member 16 |
| SLC25A24 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 |
| SMG5 | SMG5 nonsense mediated mRNA decay factor |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 |
| SOD2 | superoxide dismutase 2, mitochondrial |
| STX2 | syntaxin 2 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 |
| TCAF1 | TRPM8 channel-associated factor 1 |
| TCF3 | transcription factor 3 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TGFBI | transforming growth factor, beta-induced, 68kDa |
| THBS1 | thrombospondin 1 |
| TPI1 | triosephosphate isomerase 1 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| UBE2D1 | ubiquitin-conjugating enzyme E2D 1 |
| UBL3 | ubiquitin-like 3 |
| UTRN | utrophin |
| VPS13D | vacuolar protein sorting 13 homolog D (S. cerevisiae) |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZNF304 | zinc finger protein 304 |
| ZNF426 | zinc finger protein 426 |
| Symbol | Name |
|---|---|
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 |
| ADCY6 | adenylate cyclase 6 |
| AMBRA1 | autophagy/beclin-1 regulator 1 |
| ANKRD10 | ankyrin repeat domain 10 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
| ARFGAP1 | ADP-ribosylation factor GTPase activating protein 1 |
| B4GALT2 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) |
| BRD7 | bromodomain containing 7 |
| C10ORF88 | chromosome 10 open reading frame 88 |
| C1ORF112 | chromosome 1 open reading frame 112 |
| CCNE1 | cyclin E1 |
| CCNT1 | cyclin T1 |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CEP85 | centrosomal protein 85kDa |
| CHKB | choline kinase beta |
| CHML | choroideremia-like (Rab escort protein 2) |
| CNTD2 | cyclin N-terminal domain containing 2 |
| CTDNEP1 | CTD nuclear envelope phosphatase 1 |
| CTSK | cathepsin K |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal |
| DESI1 | desumoylating isopeptidase 1 |
| DLL3 | delta-like 3 (Drosophila) |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| DYRK4 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 |
| ECHDC2 | enoyl CoA hydratase domain containing 2 |
| EFNA3 | ephrin-A3 |
| FAM173A | family with sequence similarity 173, member A |
| FAM64A | family with sequence similarity 64, member A |
| FPGS | folylpolyglutamate synthase |
| FZD4 | frizzled class receptor 4 |
| GALNT11 | polypeptide N-acetylgalactosaminyltransferase 11 |
| GPR27 | G protein-coupled receptor 27 |
| GTPBP6 | GTP binding protein 6 (putative) |
| HPS6 | Hermansky-Pudlak syndrome 6 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IL15RA | interleukin 15 receptor, alpha |
| IL6 | interleukin 6 |
| KIF13B | kinesin family member 13B |
| KIFC1 | kinesin family member C1 |
| KRT34 | keratin 34, type I |
| LIAS | lipoic acid synthetase |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAGEF1 | melanoma antigen family F1 |
| MBIP | MAP3K12 binding inhibitory protein 1 |
| MGMT | O-6-methylguanine-DNA methyltransferase |
| MITF | microphthalmia-associated transcription factor |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 |
| MPC1 | mitochondrial pyruvate carrier 1 |
| MT1HL1 | metallothionein 1H-like 1 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like |
| NACC2 | NACC family member 2, BEN and BTB (POZ) domain containing |
| NLRX1 | NLR family member X1 |
| NMNAT2 | nicotinamide nucleotide adenylyltransferase 2 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| NVL | nuclear VCP-like |
| NXPH4 | neurexophilin 4 |
| P3H4 | prolyl 3-hydroxylase family member 4 (non-enzymatic) |
| PADI1 | peptidyl arginine deiminase, type I |
| PAQR3 | progestin and adipoQ receptor family member III |
| PCGF1 | polycomb group ring finger 1 |
| PDK2 | pyruvate dehydrogenase kinase, isozyme 2 |
| PGM3 | phosphoglucomutase 3 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| POLD1 | polymerase (DNA directed), delta 1, catalytic subunit |
| PPP4C | protein phosphatase 4, catalytic subunit |
| PSG4 | pregnancy specific beta-1-glycoprotein 4 |
| PYGB | phosphorylase, glycogen; brain |
| RANBP17 | RAN binding protein 17 |
| RCOR3 | REST corepressor 3 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| RIT1 | Ras-like without CAAX 1 |
| RNF123 | ring finger protein 123 |
| RPL39L | ribosomal protein L39-like |
| SCAMP5 | secretory carrier membrane protein 5 |
| SCNM1 | sodium channel modifier 1 |
| SCO2 | SCO2 cytochrome c oxidase assembly protein |
| SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha |
| SH3GL1 | SH3-domain GRB2-like 1 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SLC39A1 | solute carrier family 39 (zinc transporter), member 1 |
| SLC39A7 | solute carrier family 39 (zinc transporter), member 7 |
| SNX15 | sorting nexin 15 |
| SPDL1 | spindle apparatus coiled-coil protein 1 |
| SREBF1 | sterol regulatory element binding transcription factor 1 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) |
| SURF2 | surfeit 2 |
| TCTN2 | tectonic family member 2 |
| TSPAN32 | tetraspanin 32 |
| TWSG1 | twisted gastrulation BMP signaling modulator 1 |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| WDR13 | WD repeat domain 13 |
| ZNF394 | zinc finger protein 394 |