| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the captopril-1988 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACBD3 | acyl-CoA binding domain containing 3 |
| ACP6 | acid phosphatase 6, lysophosphatidic |
| ACPP | acid phosphatase, prostate |
| ATG4B | autophagy related 4B, cysteine peptidase |
| ATP6V0E1 | ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 |
| CALM3 | calmodulin 3 (phosphorylase kinase, delta) |
| CBY1 | chibby homolog 1 (Drosophila) |
| CCR1 | chemokine (C-C motif) receptor 1 |
| CDK10 | cyclin-dependent kinase 10 |
| CELF1 | CUGBP, Elav-like family member 1 |
| CHD3 | chromodomain helicase DNA binding protein 3 |
| CLPTM1 | cleft lip and palate associated transmembrane protein 1 |
| CMPK1 | cytidine monophosphate (UMP-CMP) kinase 1, cytosolic |
| CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like |
| CYB561 | cytochrome b561 |
| DKFZP434C153 | DKFZP434C153 protein |
| DPYSL2 | dihydropyrimidinase-like 2 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) |
| FAM102A | family with sequence similarity 102, member A |
| FAM53B | family with sequence similarity 53, member B |
| FTO | fat mass and obesity associated |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 |
| GBAP1 | glucosidase, beta, acid pseudogene 1 |
| GBF1 | golgi brefeldin A resistant guanine nucleotide exchange factor 1 |
| GGCX | gamma-glutamyl carboxylase |
| GON4L | gon-4-like (C. elegans) |
| HGF | hepatocyte growth factor (hepapoietin A; scatter factor) |
| HP | haptoglobin |
| IGKV1D-13 | immunoglobulin kappa variable 1D-13 |
| IMPACT | impact RWD domain protein |
| JAG1 | jagged 1 |
| KCNQ1 | potassium channel, voltage gated KQT-like subfamily Q, member 1 |
| KHSRP | KH-type splicing regulatory protein |
| LMNA | lamin A/C |
| LPAR1 | lysophosphatidic acid receptor 1 |
| LRCH4 | leucine-rich repeats and calponin homology (CH) domain containing 4 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| LUZP1 | leucine zipper protein 1 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 |
| MAP2K7 | mitogen-activated protein kinase kinase 7 |
| MAPK3 | mitogen-activated protein kinase 3 |
| MEF2D | myocyte enhancer factor 2D |
| MLYCD | malonyl-CoA decarboxylase |
| MMP2 | matrix metallopeptidase 2 |
| MTA1 | metastasis associated 1 |
| MTMR6 | myotubularin related protein 6 |
| MUM1 | melanoma associated antigen (mutated) 1 |
| NACAP1 | nascent-polypeptide-associated complex alpha polypeptide pseudogene 1 |
| NEK7 | NIMA-related kinase 7 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 |
| NOP14-AS1 | NOP14 antisense RNA 1 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| ORAI2 | ORAI calcium release-activated calcium modulator 2 |
| PCDH7 | protocadherin 7 |
| PDCL | phosducin-like |
| PIDD1 | p53-induced death domain protein 1 |
| PLCD1 | phospholipase C, delta 1 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa |
| PON2 | paraoxonase 2 |
| PPM1F | protein phosphatase, Mg2+/Mn2+ dependent, 1F |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme |
| PPP2R4 | protein phosphatase 2A activator, regulatory subunit 4 |
| PRRG1 | proline rich Gla (G-carboxyglutamic acid) 1 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| PTMA | prothymosin, alpha |
| QKI | QKI, KH domain containing, RNA binding |
| RAB3A | RAB3A, member RAS oncogene family |
| RAP1GAP | RAP1 GTPase activating protein |
| RPS11 | ribosomal protein S11 |
| RREB1 | ras responsive element binding protein 1 |
| RTN2 | reticulon 2 |
| RUNX1 | runt-related transcription factor 1 |
| SBNO2 | strawberry notch homolog 2 (Drosophila) |
| SCYL3 | SCY1-like 3 (S. cerevisiae) |
| SF3A2 | splicing factor 3a, subunit 2, 66kDa |
| SFN | stratifin |
| SGSM3 | small G protein signaling modulator 3 |
| SHROOM2 | shroom family member 2 |
| SLC25A44 | solute carrier family 25, member 44 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 |
| SLIRP | SRA stem-loop interacting RNA binding protein |
| SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 |
| SMC5 | structural maintenance of chromosomes 5 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 |
| STX1A | syntaxin 1A (brain) |
| SUSD6 | sushi domain containing 6 |
| TBC1D4 | TBC1 domain family, member 4 |
| TCF4 | transcription factor 4 |
| TRAPPC10 | trafficking protein particle complex 10 |
| TRMT12 | tRNA methyltransferase 12 homolog (S. cerevisiae) |
| TUBA3C | tubulin, alpha 3c |
| TUBB3 | tubulin, beta 3 class III |
| VAC14 | Vac14 homolog (S. cerevisiae) |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) |
| XAB2 | XPA binding protein 2 |
| ZNF821 | zinc finger protein 821 |
| Symbol | Name |
|---|---|
| ABHD17A | abhydrolase domain containing 17A |
| AIDA | axin interactor, dorsalization associated |
| ALDH18A1 | aldehyde dehydrogenase 18 family, member A1 |
| APH1A | APH1A gamma secretase subunit |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 |
| ATAD2 | ATPase family, AAA domain containing 2 |
| ATF6 | activating transcription factor 6 |
| AZU1 | azurocidin 1 |
| B4GALT2 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 |
| BCAP31 | B-cell receptor-associated protein 31 |
| BSG | basigin (Ok blood group) |
| C14ORF159 | chromosome 14 open reading frame 159 |
| C8ORF33 | chromosome 8 open reading frame 33 |
| CAPNS1 | calpain, small subunit 1 |
| CAPRIN1 | cell cycle associated protein 1 |
| CCL2 | chemokine (C-C motif) ligand 2 |
| CDC37 | cell division cycle 37 |
| CEP85 | centrosomal protein 85kDa |
| CLDND1 | claudin domain containing 1 |
| CLPB | ClpB homolog, mitochondrial AAA ATPase chaperonin |
| COQ9 | coenzyme Q9 |
| CYBA | cytochrome b-245, alpha polypeptide |
| CYC1 | cytochrome c-1 |
| DDA1 | DET1 and DDB1 associated 1 |
| DEAF1 | DEAF1 transcription factor |
| DESI1 | desumoylating isopeptidase 1 |
| DHX8 | DEAH (Asp-Glu-Ala-His) box polypeptide 8 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| ERP29 | endoplasmic reticulum protein 29 |
| FAM206A | family with sequence similarity 206, member A |
| FHL3 | four and a half LIM domains 3 |
| FXYD5 | FXYD domain containing ion transport regulator 5 |
| GBAS | glioblastoma amplified sequence |
| GDE1 | glycerophosphodiester phosphodiesterase 1 |
| GOLGA8B | golgin A8 family, member B |
| GSR | glutathione reductase |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| GYS1 | glycogen synthase 1 (muscle) |
| H2BFS | H2B histone family, member S (pseudogene) |
| HIRA | histone cell cycle regulator |
| HNRNPF | heterogeneous nuclear ribonucleoprotein F |
| HS1BP3 | HCLS1 binding protein 3 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| KIFC1 | kinesin family member C1 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) |
| MAGOH | mago-nashi homolog, proliferation-associated (Drosophila) |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 |
| MECR | mitochondrial trans-2-enoyl-CoA reductase |
| MFSD5 | major facilitator superfamily domain containing 5 |
| MLF2 | myeloid leukemia factor 2 |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MRPS15 | mitochondrial ribosomal protein S15 |
| NELFCD | negative elongation factor complex member C/D |
| NMD3 | NMD3 ribosome export adaptor |
| NME6 | NME/NM23 nucleoside diphosphate kinase 6 |
| P2RX1 | purinergic receptor P2X, ligand gated ion channel, 1 |
| P2RX4 | purinergic receptor P2X, ligand gated ion channel, 4 |
| PCBD1 | pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha |
| PEMT | phosphatidylethanolamine N-methyltransferase |
| PGD | phosphogluconate dehydrogenase |
| PHACTR4 | phosphatase and actin regulator 4 |
| PLP2 | proteolipid protein 2 (colonic epithelium-enriched) |
| PMPCA | peptidase (mitochondrial processing) alpha |
| PMVK | phosphomevalonate kinase |
| POGK | pogo transposable element with KRAB domain |
| POLR2J | polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa |
| POLR2J2 | polymerase (RNA) II (DNA directed) polypeptide J2 |
| PPP1CA | protein phosphatase 1, catalytic subunit, alpha isozyme |
| PRKAG1 | protein kinase, AMP-activated, gamma 1 non-catalytic subunit |
| PRMT5 | protein arginine methyltransferase 5 |
| PRRC1 | proline-rich coiled-coil 1 |
| PSAT1 | phosphoserine aminotransferase 1 |
| PSENEN | presenilin enhancer gamma secretase subunit |
| PSMC3 | proteasome (prosome, macropain) 26S subunit, ATPase, 3 |
| PTGES2 | prostaglandin E synthase 2 |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RHOG | ras homolog family member G |
| RPE | ribulose-5-phosphate-3-epimerase |
| RUVBL1 | RuvB-like AAA ATPase 1 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 |
| SLC25A40 | solute carrier family 25, member 40 |
| SLC31A1 | solute carrier family 31 (copper transporter), member 1 |
| SLC35C2 | solute carrier family 35 (GDP-fucose transporter), member C2 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 |
| SMARCB1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 |
| SMU1 | smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) |
| SP140L | SP140 nuclear body protein-like |
| STIP1 | stress-induced phosphoprotein 1 |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa |
| THOC6 | THO complex 6 |
| TMEM230 | transmembrane protein 230 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| UBE2M | ubiquitin-conjugating enzyme E2M |
| USP39 | ubiquitin specific peptidase 39 |
| YIPF5 | Yip1 domain family, member 5 |
| ZFP36 | ZFP36 ring finger protein |
| ZNF124 | zinc finger protein 124 |
| ZNF195 | zinc finger protein 195 |
