carbachol-3042 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the carbachol-3042 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD6 abhydrolase domain containing 6
ACHE acetylcholinesterase (Yt blood group)
ACOXL acyl-CoA oxidase-like
ACSM1 acyl-CoA synthetase medium-chain family member 1
ADORA3 adenosine A3 receptor
AK1 adenylate kinase 1
AKR1C4 aldo-keto reductase family 1, member C4
ALOX5 arachidonate 5-lipoxygenase
ANGPT4 angiopoietin 4
AP1M2 adaptor-related protein complex 1, mu 2 subunit
APOL3 apolipoprotein L, 3
AREG amphiregulin
ASCL1 achaete-scute family bHLH transcription factor 1
C10ORF95 chromosome 10 open reading frame 95
C11ORF63 chromosome 11 open reading frame 63
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CARD10 caspase recruitment domain family, member 10
CCDC170 coiled-coil domain containing 170
CCDC9 coiled-coil domain containing 9
CCL20 chemokine (C-C motif) ligand 20
CD163 CD163 molecule
CLDN9 claudin 9
CLTC clathrin, heavy chain (Hc)
COL6A1 collagen, type VI, alpha 1
CREBBP CREB binding protein
CTSF cathepsin F
DRD2 dopamine receptor D2
DUSP1 dual specificity phosphatase 1
EPHA4 EPH receptor A4
EPS8L1 EPS8-like 1
ERBB3 erb-b2 receptor tyrosine kinase 3
FAM65B family with sequence similarity 65, member B
FGFR1 fibroblast growth factor receptor 1
FKBP5 FK506 binding protein 5
FLT3 fms-related tyrosine kinase 3
GABARAPL3 GABA(A) receptors associated protein like 3, pseudogene
GAS8 growth arrest-specific 8
GHRH growth hormone releasing hormone
GLS2 glutaminase 2 (liver, mitochondrial)
GPR161 G protein-coupled receptor 161
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
IDS iduronate 2-sulfatase
IGFBP5 insulin-like growth factor binding protein 5
IL1R2 interleukin 1 receptor, type II
INSL5 insulin-like 5
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains)
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KCNK1 potassium channel, two pore domain subfamily K, member 1
KIF26B kinesin family member 26B
KIR2DL4 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4
KLK10 kallikrein-related peptidase 10
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LHX6 LIM homeobox 6
LMNA lamin A/C
LOC647070 uncharacterized LOC647070
LRRC37BP1 leucine rich repeat containing 37B pseudogene 1
MAN1A2 mannosidase, alpha, class 1A, member 2
MED16 mediator complex subunit 16
MEIS3P1 Meis homeobox 3 pseudogene 1
MTUS1 microtubule associated tumor suppressor 1
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
NR2F2 nuclear receptor subfamily 2, group F, member 2
OLAH oleoyl-ACP hydrolase
PCDH11Y protocadherin 11 Y-linked
PER1 period circadian clock 1
PLA2G2E phospholipase A2, group IIE
PLEK2 pleckstrin 2
PLSCR3 phospholipid scramblase 3
PPP4R4 protein phosphatase 4, regulatory subunit 4
PSG1 pregnancy specific beta-1-glycoprotein 1
PTGDR2 prostaglandin D2 receptor 2
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RHOH ras homolog family member H
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe)
SCARB2 scavenger receptor class B, member 2
SCARF1 scavenger receptor class F, member 1
SHOX2 short stature homeobox 2
SIGLEC7 sialic acid binding Ig-like lectin 7
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC48A1 solute carrier family 48 (heme transporter), member 1
SRF serum response factor (c-fos serum response element-binding transcription factor)
SRRM2 serine/arginine repetitive matrix 2
SSH3 slingshot protein phosphatase 3
STMN4 stathmin-like 4
STX11 syntaxin 11
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
TAS2R1 taste receptor, type 2, member 1
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
TK2 thymidine kinase 2, mitochondrial
TMOD1 tropomodulin 1
TRIL TLR4 interactor with leucine-rich repeats
TRIM3 tripartite motif containing 3
TSC22D3 TSC22 domain family, member 3
YTHDC2 YTH domain containing 2
ZBTB16 zinc finger and BTB domain containing 16
ZCCHC4 zinc finger, CCHC domain containing 4
ZFHX3 zinc finger homeobox 3

decreased expression

Symbol Name
ABHD4 abhydrolase domain containing 4
ABI3BP ABI family, member 3 (NESH) binding protein
ACPP acid phosphatase, prostate
ADAP2 ArfGAP with dual PH domains 2
ALDOAP2 aldolase A, fructose-bisphosphate pseudogene 2
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
ARL15 ADP-ribosylation factor-like 15
BSPRY B-box and SPRY domain containing
C17ORF53 chromosome 17 open reading frame 53
C1ORF159 chromosome 1 open reading frame 159
C5ORF45 chromosome 5 open reading frame 45
C7ORF43 chromosome 7 open reading frame 43
C9ORF9 chromosome 9 open reading frame 9
CAMTA2 calmodulin binding transcription activator 2
CCL2 chemokine (C-C motif) ligand 2
CD3D CD3d molecule, delta (CD3-TCR complex)
CD82 CD82 molecule
CTPS2 CTP synthase 2
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
DYSF dysferlin
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
ELAC1 elaC ribonuclease Z 1
ENAH enabled homolog (Drosophila)
ENO2 enolase 2 (gamma, neuronal)
ETV4 ets variant 4
FGF23 fibroblast growth factor 23
FGF6 fibroblast growth factor 6
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4
GDAP1 ganglioside induced differentiation associated protein 1
GJA1 gap junction protein, alpha 1, 43kDa
GLCE glucuronic acid epimerase
GPR3 G protein-coupled receptor 3
HIST1H1B histone cluster 1, H1b
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HRAS Harvey rat sarcoma viral oncogene homolog
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KIAA0753 KIAA0753
KPNA5 karyopherin alpha 5 (importin alpha 6)
KPTN kaptin (actin binding protein)
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LTB lymphotoxin beta (TNF superfamily, member 3)
LTBP2 latent transforming growth factor beta binding protein 2
LY6D lymphocyte antigen 6 complex, locus D
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MBNL3 muscleblind-like splicing regulator 3
MFSD11 major facilitator superfamily domain containing 11
MKRN3 makorin ring finger protein 3
MRAS muscle RAS oncogene homolog
MX2 MX dynamin-like GTPase 2
NME8 NME/NM23 family member 8
NSUN6 NOP2/Sun domain family, member 6
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PCNXL4 pecanex-like 4 (Drosophila)
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PLS1 plastin 1
PRSS53 protease, serine, 53
PTPRS protein tyrosine phosphatase, receptor type, S
RCAN3 RCAN family member 3
RHOBTB1 Rho-related BTB domain containing 1
RPL23AP32 ribosomal protein L23a pseudogene 32
RWDD2A RWD domain containing 2A
SCAMP4 secretory carrier membrane protein 4
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2
SETD1A SET domain containing 1A
SH2D3C SH2 domain containing 3C
SIRT6 sirtuin 6
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3
SLC17A2 solute carrier family 17, member 2
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC38A6 solute carrier family 38, member 6
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SMR3A submaxillary gland androgen regulated protein 3A
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SPATA2L spermatogenesis associated 2-like
SPI1 Spi-1 proto-oncogene
ST8SIA5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
SV2A synaptic vesicle glycoprotein 2A
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
THBS3 thrombospondin 3
TMEM110 transmembrane protein 110
TMEM212 transmembrane protein 212
TRIM9 tripartite motif containing 9
TSC22D4 TSC22 domain family, member 4
TUFT1 tuftelin 1
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UPK3A uroplakin 3A
WASF3 WAS protein family, member 3
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
ZBED1 zinc finger, BED-type containing 1
ZBTB6 zinc finger and BTB domain containing 6
ZNF16 zinc finger protein 16
ZNF493 zinc finger protein 493