carbachol-3380 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the carbachol-3380 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ANGPTL2 angiopoietin-like 2
ANKMY1 ankyrin repeat and MYND domain containing 1
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
C1ORF95 chromosome 1 open reading frame 95
CADM3 cell adhesion molecule 3
CALD1 caldesmon 1
CD4 CD4 molecule
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CLIC5 chloride intracellular channel 5
COL16A1 collagen, type XVI, alpha 1
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CREBZF CREB/ATF bZIP transcription factor
CST4 cystatin S
CTSZ cathepsin Z
CXORF21 chromosome X open reading frame 21
CXXC4 CXXC finger protein 4
DCN decorin
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DEFA5 defensin, alpha 5, Paneth cell-specific
DIO2 deiodinase, iodothyronine, type II
EAF2 ELL associated factor 2
EMP3 epithelial membrane protein 3
EPB41L4A erythrocyte membrane protein band 4.1 like 4A
ERC1 ELKS/RAB6-interacting/CAST family member 1
ERO1LB ERO1-like beta (S. cerevisiae)
FABP7 fatty acid binding protein 7, brain
FAM135A family with sequence similarity 135, member A
FAM76A family with sequence similarity 76, member A
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FLJ11292
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
GLP1R glucagon-like peptide 1 receptor
GM2A GM2 ganglioside activator
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPR68 G protein-coupled receptor 68
GRIK5 glutamate receptor, ionotropic, kainate 5
GRIP2 glutamate receptor interacting protein 2
GSTA1 glutathione S-transferase alpha 1
GSTA3 glutathione S-transferase alpha 3
HCG4 HLA complex group 4 (non-protein coding)
HFE hemochromatosis
HIST1H3E histone cluster 1, H3e
HIST1H3F histone cluster 1, H3f
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
ICOSLG inducible T-cell co-stimulator ligand
IL2RB interleukin 2 receptor, beta
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
LARP4B La ribonucleoprotein domain family, member 4B
LINC00216 long intergenic non-protein coding RNA 216
LOC729164 hCG1732469
MAOA monoamine oxidase A
MED12 mediator complex subunit 12
METTL7A methyltransferase like 7A
MVB12B multivesicular body subunit 12B
MX1 MX dynamin-like GTPase 1
MYCNOS MYCN opposite strand
MYOZ2 myozenin 2
NPY2R neuropeptide Y receptor Y2
PAK7 p21 protein (Cdc42/Rac)-activated kinase 7
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PDE4DIP phosphodiesterase 4D interacting protein
PKNOX1 PBX/knotted 1 homeobox 1
PPARA peroxisome proliferator-activated receptor alpha
PSG6 pregnancy specific beta-1-glycoprotein 6
PTPRM protein tyrosine phosphatase, receptor type, M
RAB40C RAB40C, member RAS oncogene family
RAB6A RAB6A, member RAS oncogene family
RAI1 retinoic acid induced 1
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RPH3A rabphilin 3A
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe)
SARM1 sterile alpha and TIR motif containing 1
SCUBE3 signal peptide, CUB domain, EGF-like 3
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SLCO1A2 solute carrier organic anion transporter family, member 1A2
SOX10 SRY (sex determining region Y)-box 10
SOX2 SRY (sex determining region Y)-box 2
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SPRED2 sprouty-related, EVH1 domain containing 2
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SULT4A1 sulfotransferase family 4A, member 1
TEF thyrotrophic embryonic factor
TMCC2 transmembrane and coiled-coil domain family 2
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TNNT2 troponin T type 2 (cardiac)
TRPM2 transient receptor potential cation channel, subfamily M, member 2
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble

decreased expression

Symbol Name
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8
ACTL8 actin-like 8
ATHL1 ATH1, acid trehalase-like 1 (yeast)
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
C14ORF79 chromosome 14 open reading frame 79
C19ORF73 chromosome 19 open reading frame 73
C8ORF60 chromosome 8 open reading frame 60
CBR4 carbonyl reductase 4
CBX8 chromobox homolog 8
CCNK cyclin K
CCP110 centriolar coiled coil protein 110kDa
CD82 CD82 molecule
CHRM3 cholinergic receptor, muscarinic 3
CIC capicua transcriptional repressor
CLGN calmegin
CORO7 coronin 7
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DGAT1 diacylglycerol O-acyltransferase 1
DPY19L1P1 DPY19L1 pseudogene 1
ETV6 ets variant 6
F2R coagulation factor II (thrombin) receptor
FAIM Fas apoptotic inhibitory molecule
FAM212B family with sequence similarity 212, member B
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GPR27 G protein-coupled receptor 27
HDAC5 histone deacetylase 5
HIST1H1D histone cluster 1, H1d
HIST1H2BC histone cluster 1, H2bc
HOXC8 homeobox C8
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
IFT54 intraflagellar transport 54
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KDM8 lysine (K)-specific demethylase 8
KIAA0319L KIAA0319-like
KIAA0355 KIAA0355
KIF13A kinesin family member 13A
KRT24 keratin 24, type I
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LAMP3 lysosomal-associated membrane protein 3
LARP6 La ribonucleoprotein domain family, member 6
LIME1 Lck interacting transmembrane adaptor 1
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
MEFV Mediterranean fever
MRPS18C mitochondrial ribosomal protein S18C
MT1H metallothionein 1H
MVP major vault protein
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NPM3 nucleophosmin/nucleoplasmin 3
NYNRIN NYN domain and retroviral integrase containing
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OSGIN1 oxidative stress induced growth inhibitor 1
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PHF14 PHD finger protein 14
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLCD1 phospholipase C, delta 1
PPP1R9A protein phosphatase 1, regulatory subunit 9A
RAB30 RAB30, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RGS19 regulator of G-protein signaling 19
RHBG Rh family, B glycoprotein (gene/pseudogene)
RIN2 Ras and Rab interactor 2
RNF208 ring finger protein 208
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RRAGB Ras-related GTP binding B
RUNDC3B RUN domain containing 3B
SAYSD1 SAYSVFN motif domain containing 1
SECTM1 secreted and transmembrane 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SETD1A SET domain containing 1A
SKI SKI proto-oncogene
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLPI secretory leukocyte peptidase inhibitor
SPEG SPEG complex locus
SPIDR scaffolding protein involved in DNA repair
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
ST5 suppression of tumorigenicity 5
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TICAM1 toll-like receptor adaptor molecule 1
TMC5 transmembrane channel-like 5
TMPRSS4 transmembrane protease, serine 4
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNS2 tensin 2
TPST1 tyrosylprotein sulfotransferase 1
TSC22D4 TSC22 domain family, member 4
UPK3B uroplakin 3B
VIPR1 vasoactive intestinal peptide receptor 1
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WDR62 WD repeat domain 62
XDH xanthine dehydrogenase
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZIC3 Zic family member 3
ZNF226 zinc finger protein 226
ZNF639 zinc finger protein 639
ZNF768 zinc finger protein 768