carbachol-5342 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the carbachol-5342 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
ABHD6 abhydrolase domain containing 6
AK1 adenylate kinase 1
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANP32A-IT1 ANP32A intronic transcript 1
ARMC4 armadillo repeat containing 4
C10ORF95 chromosome 10 open reading frame 95
C17ORF53 chromosome 17 open reading frame 53
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CACNB2 calcium channel, voltage-dependent, beta 2 subunit
CACTIN cactin, spliceosome C complex subunit
CAMK4 calcium/calmodulin-dependent protein kinase IV
CASZ1 castor zinc finger 1
CD6 CD6 molecule
CEMIP cell migration inducing protein, hyaluronan binding
CFLAR CASP8 and FADD-like apoptosis regulator
COMT catechol-O-methyltransferase
CPTP ceramide-1-phosphate transfer protein
CRY2 cryptochrome circadian clock 2
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
FBXO31 F-box protein 31
FBXO38 F-box protein 38
GON4L gon-4-like (C. elegans)
GRB10 growth factor receptor-bound protein 10
HSPB11 heat shock protein family B (small), member 11
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
INHBA inhibin, beta A
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
IRF5 interferon regulatory factor 5
ITSN1 intersectin 1 (SH3 domain protein)
KCNIP1 Kv channel interacting protein 1
KIF3C kinesin family member 3C
KLK5 kallikrein-related peptidase 5
LIN7A lin-7 homolog A (C. elegans)
LOC399491
LONP2 lon peptidase 2, peroxisomal
LRRC20 leucine rich repeat containing 20
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LYN LYN proto-oncogene, Src family tyrosine kinase
MAP4 microtubule-associated protein 4
MAPK11 mitogen-activated protein kinase 11
MNDA myeloid cell nuclear differentiation antigen
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MTA1 metastasis associated 1
MYL10 myosin, light chain 10, regulatory
MYL4 myosin, light chain 4, alkali; atrial, embryonic
MZF1 myeloid zinc finger 1
N4BP3 NEDD4 binding protein 3
NCR2 natural cytotoxicity triggering receptor 2
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa
NEB nebulin
NF2 neurofibromin 2 (merlin)
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NKX3-1 NK3 homeobox 1
NPR2 natriuretic peptide receptor 2
NUDT7 nudix (nucleoside diphosphate linked moiety X)-type motif 7
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OGFOD2 2-oxoglutarate and iron-dependent oxygenase domain containing 2
ONECUT2 one cut homeobox 2
PCGF2 polycomb group ring finger 2
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLCH1 phospholipase C, eta 1
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
PML promyelocytic leukemia
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F
PPT2 palmitoyl-protein thioesterase 2
PTPN1 protein tyrosine phosphatase, non-receptor type 1
ROM1 retinal outer segment membrane protein 1
S100A9 S100 calcium binding protein A9
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SIX1 SIX homeobox 1
SIX3 SIX homeobox 3
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLC46A3 solute carrier family 46, member 3
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SMAD4 SMAD family member 4
SOCS1 suppressor of cytokine signaling 1
SPAG8 sperm associated antigen 8
SPINK5 serine peptidase inhibitor, Kazal type 5
STAT5B signal transducer and activator of transcription 5B
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast)
TMEM62 transmembrane protein 62
TRAK1 trafficking protein, kinesin binding 1
TRIM21 tripartite motif containing 21
TTLL5 tubulin tyrosine ligase-like family member 5
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UNC5B unc-5 homolog B (C. elegans)
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae)
WNT6 wingless-type MMTV integration site family, member 6
ZBTB48 zinc finger and BTB domain containing 48
ZHX3 zinc fingers and homeoboxes 3
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF589 zinc finger protein 589

decreased expression

Symbol Name
ABLIM3 actin binding LIM protein family, member 3
ACTR6 ARP6 actin-related protein 6 homolog (yeast)
ACVR1 activin A receptor, type I
ADGRE5 adhesion G protein-coupled receptor E5
AEN apoptosis enhancing nuclease
AHDC1 AT hook, DNA binding motif, containing 1
AIDA axin interactor, dorsalization associated
ANKRD28 ankyrin repeat domain 28
ANXA1 annexin A1
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1
AUH AU RNA binding protein/enoyl-CoA hydratase
BRD9 bromodomain containing 9
C11ORF95 chromosome 11 open reading frame 95
C16ORF59 chromosome 16 open reading frame 59
C2ORF44 chromosome 2 open reading frame 44
C5ORF45 chromosome 5 open reading frame 45
C7ORF43 chromosome 7 open reading frame 43
CASD1 CAS1 domain containing 1
CCS copper chaperone for superoxide dismutase
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CEP85 centrosomal protein 85kDa
CHML choroideremia-like (Rab escort protein 2)
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CLK1 CDC-like kinase 1
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
COL4A5 collagen, type IV, alpha 5
COQ6 coenzyme Q6 monooxygenase
ETAA1 Ewing tumor-associated antigen 1
EYA2 EYA transcriptional coactivator and phosphatase 2
FGD6 FYVE, RhoGEF and PH domain containing 6
FKBPL FK506 binding protein like
FLRT3 fibronectin leucine rich transmembrane protein 3
FMO4 flavin containing monooxygenase 4
GLI3 GLI family zinc finger 3
GLMN glomulin, FKBP associated protein
GPATCH1 G patch domain containing 1
HSPA2 heat shock 70kDa protein 2
HYAL2 hyaluronoglucosaminidase 2
IFI6 interferon, alpha-inducible protein 6
INPP5K inositol polyphosphate-5-phosphatase K
JOSD1 Josephin domain containing 1
KAT2A K(lysine) acetyltransferase 2A
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KIAA0894 KIAA0894 protein
KIFAP3 kinesin-associated protein 3
KLC2 kinesin light chain 2
KLF10 Kruppel-like factor 10
KLHL26 kelch-like family member 26
KPNA4 karyopherin alpha 4 (importin alpha 3)
KRBOX4 KRAB box domain containing 4
MBTPS2 membrane-bound transcription factor peptidase, site 2
MEIS2 Meis homeobox 2
MXRA7 matrix-remodelling associated 7
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NDE1 nudE neurodevelopment protein 1
NPFFR1 neuropeptide FF receptor 1
NSD1 nuclear receptor binding SET domain protein 1
PEX13 peroxisomal biogenesis factor 13
PIGH phosphatidylinositol glycan anchor biosynthesis, class H
PLA2G12A phospholipase A2, group XIIA
PLA2G15 phospholipase A2, group XV
POR P450 (cytochrome) oxidoreductase
PPAN peter pan homolog (Drosophila)
PPP6R3 protein phosphatase 6, regulatory subunit 3
PTPRU protein tyrosine phosphatase, receptor type, U
QPRT quinolinate phosphoribosyltransferase
RAPGEF6 Rap guanine nucleotide exchange factor (GEF) 6
RBM38 RNA binding motif protein 38
REPS2 RALBP1 associated Eps domain containing 2
RHOC ras homolog family member C
RIBC2 RIB43A domain with coiled-coils 2
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
SETD8 SET domain containing (lysine methyltransferase) 8
SFT2D2 SFT2 domain containing 2
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SNHG3 small nucleolar RNA host gene 3
SNUPN snurportin 1
STXBP2 syntaxin binding protein 2
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
TBL3 transducin (beta)-like 3
TFF3 trefoil factor 3 (intestinal)
THAP4 THAP domain containing 4
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TSSC4 tumor suppressing subtransferable candidate 4
TUBG2 tubulin, gamma 2
ZFP36 ZFP36 ring finger protein
ZNF227 zinc finger protein 227
ZNF329 zinc finger protein 329
ZNF468 zinc finger protein 468
ZNF571 zinc finger protein 571
ZNF813 zinc finger protein 813
ZW10 zw10 kinetochore protein
ZXDC ZXD family zinc finger C