carbachol-6742 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the carbachol-6742 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A1CF APOBEC1 complementation factor
ADTRP androgen-dependent TFPI-regulating protein
AIPL1 aryl hydrocarbon receptor interacting protein-like 1
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ANGEL2 angel homolog 2 (Drosophila)
ARHGAP35 Rho GTPase activating protein 35
ARTN artemin
ATP9B ATPase, class II, type 9B
AURKA aurora kinase A
BMP8B bone morphogenetic protein 8b
C14ORF79 chromosome 14 open reading frame 79
C1QTNF3 C1q and tumor necrosis factor related protein 3
CACYBP calcyclin binding protein
CAMK1G calcium/calmodulin-dependent protein kinase IG
CCDC40 coiled-coil domain containing 40
CCL27 chemokine (C-C motif) ligand 27
CD22 CD22 molecule
COL10A1 collagen, type X, alpha 1
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DGKE diacylglycerol kinase, epsilon 64kDa
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
EDIL3 EGF-like repeats and discoidin I-like domains 3
EGR4 early growth response 4
ELOVL5 ELOVL fatty acid elongase 5
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
ETV6 ets variant 6
EYA4 EYA transcriptional coactivator and phosphatase 4
FAM63A family with sequence similarity 63, member A
FGFR1 fibroblast growth factor receptor 1
FOXG1 forkhead box G1
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3
GK2 glycerol kinase 2
GLP1R glucagon-like peptide 1 receptor
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GRIA3 glutamate receptor, ionotropic, AMPA 3
HEXA hexosaminidase A (alpha polypeptide)
HIPK3 homeodomain interacting protein kinase 3
HIST1H4D histone cluster 1, H4d
IL9R interleukin 9 receptor
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1
KIAA1467 KIAA1467
KRAS Kirsten rat sarcoma viral oncogene homolog
LGALS8 lectin, galactoside-binding, soluble, 8
LIPG lipase, endothelial
LOXL3 lysyl oxidase-like 3
LRRN3 leucine rich repeat neuronal 3
MAGEA5 melanoma antigen family A5
MMP10 matrix metallopeptidase 10
MNMIP1 manchette microtubule inner protein 1
MOGAT2 monoacylglycerol O-acyltransferase 2
MVD mevalonate (diphospho) decarboxylase
NCAM1 neural cell adhesion molecule 1
NME5 NME/NM23 family member 5
NPY5R neuropeptide Y receptor Y5
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OR1G1 olfactory receptor, family 1, subfamily G, member 1
PAPPA2 pappalysin 2
PCSK6 proprotein convertase subtilisin/kexin type 6
PDK3 pyruvate dehydrogenase kinase, isozyme 3
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PER2 period circadian clock 2
PODXL2 podocalyxin-like 2
PON1 paraoxonase 1
PPIAL4A peptidylprolyl isomerase A (cyclophilin A)-like 4A
PQBP1 polyglutamine binding protein 1
PRKG1 protein kinase, cGMP-dependent, type I
PVR poliovirus receptor
PVT1 Pvt1 oncogene (non-protein coding)
RB1 retinoblastoma 1
RHAG Rh-associated glycoprotein
RPS3A ribosomal protein S3A
SAMD4A sterile alpha motif domain containing 4A
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SP110 SP110 nuclear body protein
SRSF7 serine/arginine-rich splicing factor 7
SYN3 synapsin III
TBX1 T-box 1
TK2 thymidine kinase 2, mitochondrial
TNS1 tensin 1
TRIM10 tripartite motif containing 10
TSPAN9 tetraspanin 9
TTC30A tetratricopeptide repeat domain 30A
TTLL3 tubulin tyrosine ligase-like family member 3
TUBA3C tubulin, alpha 3c
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
VDAC3 voltage-dependent anion channel 3
VGLL3 vestigial-like family member 3
VNN2 vanin 2
WFDC2 WAP four-disulfide core domain 2
XIST X inactive specific transcript (non-protein coding)
ZFP30 ZFP30 zinc finger protein
ZMAT4 zinc finger, matrin-type 4
ZNF117 zinc finger protein 117
ZNF280B zinc finger protein 280B

decreased expression

Symbol Name
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ADAM2 ADAM metallopeptidase domain 2
APOC4 apolipoprotein C-IV
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARMCX4 armadillo repeat containing, X-linked 4
ATP7B ATPase, Cu++ transporting, beta polypeptide
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BAHCC1 BAH domain and coiled-coil containing 1
BMP15 bone morphogenetic protein 15
C16ORF59 chromosome 16 open reading frame 59
C1ORF159 chromosome 1 open reading frame 159
C4ORF29 chromosome 4 open reading frame 29
CARD8 caspase recruitment domain family, member 8
CASS4 Cas scaffolding protein family member 4
CD3D CD3d molecule, delta (CD3-TCR complex)
CD70 CD70 molecule
CDIP1 cell death-inducing p53 target 1
CLDN1 claudin 1
CLEC16A C-type lectin domain family 16, member A
CPPED1 calcineurin-like phosphoesterase domain containing 1
CTC1 CTS telomere maintenance complex component 1
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DBF4B DBF4 zinc finger B
DCSTAMP dendrocyte expressed seven transmembrane protein
DTX2 deltex 2, E3 ubiquitin ligase
EFNA3 ephrin-A3
EPN3 epsin 3
EPPK1 epiplakin 1
FBXL7 F-box and leucine-rich repeat protein 7
FRS3 fibroblast growth factor receptor substrate 3
FURIN furin (paired basic amino acid cleaving enzyme)
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GMIP GEM interacting protein
GREB1L growth regulation by estrogen in breast cancer-like
GRM4 glutamate receptor, metabotropic 4
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HDAC11 histone deacetylase 11
HDAC7 histone deacetylase 7
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HSPA1L heat shock 70kDa protein 1-like
HSPB6 heat shock protein, alpha-crystallin-related, B6
IBA57 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
IFT140 intraflagellar transport 140
IL11RA interleukin 11 receptor, alpha
ITGB7 integrin, beta 7
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KDM8 lysine (K)-specific demethylase 8
KIAA0754 KIAA0754
KRT15 keratin 15, type I
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LINC00597 long intergenic non-protein coding RNA 597
LPAR4 lysophosphatidic acid receptor 4
LRRC20 leucine rich repeat containing 20
LRRC6 leucine rich repeat containing 6
LRRC61 leucine rich repeat containing 61
LRRK1 leucine-rich repeat kinase 1
LY6D lymphocyte antigen 6 complex, locus D
MAP3K7CL MAP3K7 C-terminal like
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MLYCD malonyl-CoA decarboxylase
MUC3B mucin 3B, cell surface associated
MXRA8 matrix-remodelling associated 8
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NPFFR1 neuropeptide FF receptor 1
NTSR1 neurotensin receptor 1 (high affinity)
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
OVGP1 oviductal glycoprotein 1, 120kDa
PALMD palmdelphin
PAQR4 progestin and adipoQ receptor family member IV
PARP3 poly (ADP-ribose) polymerase family, member 3
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLEKHO2 pleckstrin homology domain containing, family O member 2
POLL polymerase (DNA directed), lambda
POM121 POM121 transmembrane nucleoporin
PTK6 protein tyrosine kinase 6
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RIN1 Ras and Rab interactor 1
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
SARS2 seryl-tRNA synthetase 2, mitochondrial
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SETD6 SET domain containing 6
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SNHG3 small nucleolar RNA host gene 3
SPEG SPEG complex locus
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TBC1D22B TBC1 domain family, member 22B
TIGD6 tigger transposable element derived 6
TMEM212 transmembrane protein 212
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TOM1 target of myb1 (chicken)
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
ZNF358 zinc finger protein 358
ZNF408 zinc finger protein 408
ZNF667 zinc finger protein 667
ZNF862 zinc finger protein 862