carbamazepine-1683 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the carbamazepine-1683 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACBD4 acyl-CoA binding domain containing 4
ADAM17 ADAM metallopeptidase domain 17
ADRBK1 adrenergic, beta, receptor kinase 1
ARHGAP44 Rho GTPase activating protein 44
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARL2BP ADP-ribosylation factor-like 2 binding protein
ARSB arylsulfatase B
BGN biglycan
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit
C11ORF21 chromosome 11 open reading frame 21
C19ORF66 chromosome 19 open reading frame 66
C1ORF105 chromosome 1 open reading frame 105
CD70 CD70 molecule
CDON cell adhesion associated, oncogene regulated
CGREF1 cell growth regulator with EF-hand domain 1
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CIDEC cell death-inducing DFFA-like effector c
CNGB3 cyclic nucleotide gated channel beta 3
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
CYR61 cysteine-rich, angiogenic inducer, 61
DCTN1 dynactin 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EEA1 early endosome antigen 1
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
ETAA1 Ewing tumor-associated antigen 1
F2RL2 coagulation factor II (thrombin) receptor-like 2
FAM134B family with sequence similarity 134, member B
FOXN3 forkhead box N3
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GLB1L galactosidase, beta 1-like
GPSM3 G-protein signaling modulator 3
GSPT1 G1 to S phase transition 1
GSTM5 glutathione S-transferase mu 5
HBS1L HBS1-like translational GTPase
HEMK1 HemK methyltransferase family member 1
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HFE hemochromatosis
ICAM1 intercellular adhesion molecule 1
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFITM1 interferon induced transmembrane protein 1
IL1B interleukin 1, beta
INO80D INO80 complex subunit D
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KRT6B keratin 6B, type II
KRT75 keratin 75, type II
LIME1 Lck interacting transmembrane adaptor 1
LTBP4 latent transforming growth factor beta binding protein 4
LYPD1 LY6/PLAUR domain containing 1
MAP1A microtubule-associated protein 1A
MINK1 misshapen-like kinase 1
MTA1 metastasis associated 1
MYL10 myosin, light chain 10, regulatory
MYOZ1 myozenin 1
NCALD neurocalcin delta
NCOA2 nuclear receptor coactivator 2
NEUROD1 neuronal differentiation 1
NF2 neurofibromin 2 (merlin)
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NR2F1 nuclear receptor subfamily 2, group F, member 1
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OR1D2 olfactory receptor, family 1, subfamily D, member 2
PAIP2B poly(A) binding protein interacting protein 2B
PDE10A phosphodiesterase 10A
PDGFB platelet-derived growth factor beta polypeptide
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLCL2 phospholipase C-like 2
PML promyelocytic leukemia
PPARD peroxisome proliferator-activated receptor delta
PPP1R7 protein phosphatase 1, regulatory subunit 7
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PPP5C protein phosphatase 5, catalytic subunit
PQBP1 polyglutamine binding protein 1
PRB1 proline-rich protein BstNI subfamily 1
PRKDC protein kinase, DNA-activated, catalytic polypeptide
RPAP2 RNA polymerase II associated protein 2
SCN10A sodium channel, voltage gated, type X alpha subunit
SLC13A4 solute carrier family 13 (sodium/sulfate symporter), member 4
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SORBS3 sorbin and SH3 domain containing 3
SPN sialophorin
SRD5A3 steroid 5 alpha-reductase 3
SUGP1 SURP and G patch domain containing 1
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
TMEM212 transmembrane protein 212
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TRPM2 transient receptor potential cation channel, subfamily M, member 2
UBOX5 U-box domain containing 5
USP46 ubiquitin specific peptidase 46
ZFYVE9 zinc finger, FYVE domain containing 9
ZNF419 zinc finger protein 419
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ABHD14A abhydrolase domain containing 14A
ADGRE5 adhesion G protein-coupled receptor E5
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A
ARHGAP10 Rho GTPase activating protein 10
ARHGAP11A Rho GTPase activating protein 11A
ASTE1 asteroid homolog 1 (Drosophila)
ATP7B ATPase, Cu++ transporting, beta polypeptide
BAHD1 bromo adjacent homology domain containing 1
C11ORF68 chromosome 11 open reading frame 68
C12ORF29 chromosome 12 open reading frame 29
C14ORF132 chromosome 14 open reading frame 132
C16ORF45 chromosome 16 open reading frame 45
C6ORF47 chromosome 6 open reading frame 47
CBX7 chromobox homolog 7
CCDC47 coiled-coil domain containing 47
CCDC88C coiled-coil domain containing 88C
CCNJ cyclin J
CD81 CD81 molecule
CDKL3 cyclin-dependent kinase-like 3
CHKB choline kinase beta
CHMP7 charged multivesicular body protein 7
CLUH clustered mitochondria (cluA/CLU1) homolog
COMMD10 COMM domain containing 10
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DHRS7B dehydrogenase/reductase (SDR family) member 7B
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DOCK1 dedicator of cytokinesis 1
DUSP5 dual specificity phosphatase 5
ENO2 enolase 2 (gamma, neuronal)
EYA2 EYA transcriptional coactivator and phosphatase 2
FAM188A family with sequence similarity 188, member A
FBRS fibrosin
FJX1 four jointed box 1 (Drosophila)
GBAS glioblastoma amplified sequence
GMEB1 glucocorticoid modulatory element binding protein 1
GNPDA1 glucosamine-6-phosphate deaminase 1
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
HIRA histone cell cycle regulator
HMGB3P1 high mobility group box 3 pseudogene 1
HOXC13 homeobox C13
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
IRF2BP1 interferon regulatory factor 2 binding protein 1
KIF3B kinesin family member 3B
LAMA5 laminin, alpha 5
LAMB3 laminin, beta 3
LARS leucyl-tRNA synthetase
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAPKBP1 mitogen-activated protein kinase binding protein 1
MB myoglobin
MBOAT2 membrane bound O-acyltransferase domain containing 2
MED22 mediator complex subunit 22
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MKNK2 MAP kinase interacting serine/threonine kinase 2
MYL5 myosin, light chain 5, regulatory
NLK nemo-like kinase
PGP phosphoglycolate phosphatase
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PISD phosphatidylserine decarboxylase
PKN1 protein kinase N1
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PMP22 peripheral myelin protein 22
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2
PRICKLE3 prickle homolog 3 (Drosophila)
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1
PTK6 protein tyrosine kinase 6
PTPRU protein tyrosine phosphatase, receptor type, U
PYGL phosphorylase, glycogen, liver
QTRT1 queuine tRNA-ribosyltransferase 1
RBM42 RNA binding motif protein 42
RFTN1 raftlin, lipid raft linker 1
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RSAD1 radical S-adenosyl methionine domain containing 1
S100A4 S100 calcium binding protein A4
SARS2 seryl-tRNA synthetase 2, mitochondrial
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SMAD7 SMAD family member 7
SMCO4 single-pass membrane protein with coiled-coil domains 4
SOX12 SRY (sex determining region Y)-box 12
SREBF1 sterol regulatory element binding transcription factor 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
TESK2 testis-specific kinase 2
TMEM120B transmembrane protein 120B
TMEM254 transmembrane protein 254
TMPRSS3 transmembrane protease, serine 3
TMUB2 transmembrane and ubiquitin-like domain containing 2
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TOM1 target of myb1 (chicken)
TRIM25 tripartite motif containing 25
TUBA4A tubulin, alpha 4a
TULP4 tubby like protein 4
URGCP upregulator of cell proliferation
WBP2 WW domain binding protein 2
ZBTB25 zinc finger and BTB domain containing 25
ZBTB6 zinc finger and BTB domain containing 6
ZNF276 zinc finger protein 276
ZNF552 zinc finger protein 552
ZNF573 zinc finger protein 573
ZNF778 zinc finger protein 778