carbamazepine-1805 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the carbamazepine-1805 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADCY3 adenylate cyclase 3
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APOL2 apolipoprotein L, 2
ARSB arylsulfatase B
ATP10A ATPase, class V, type 10A
ATP10D ATPase, class V, type 10D
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
ATP9B ATPase, class II, type 9B
BICD1 bicaudal D homolog 1 (Drosophila)
C16ORF45 chromosome 16 open reading frame 45
C17ORF80 chromosome 17 open reading frame 80
C2CD2L C2CD2-like
CDV3 CDV3 homolog (mouse)
CLIC4 chloride intracellular channel 4
COPS8 COP9 signalosome subunit 8
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DNAAF1 dynein, axonemal, assembly factor 1
EGFL7 EGF-like-domain, multiple 7
EML4 echinoderm microtubule associated protein like 4
EXD3 exonuclease 3'-5' domain containing 3
FBN1 fibrillin 1
FGD6 FYVE, RhoGEF and PH domain containing 6
FHL1 four and a half LIM domains 1
FNDC4 fibronectin type III domain containing 4
FOXA1 forkhead box A1
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
GPR17 G protein-coupled receptor 17
H2AFX H2A histone family, member X
HHEX hematopoietically expressed homeobox
HIRA histone cell cycle regulator
HPCAL4 hippocalcin like 4
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
IL1A interleukin 1, alpha
IL1RAP interleukin 1 receptor accessory protein
INO80B INO80 complex subunit B
ITFG2 integrin alpha FG-GAP repeat containing 2
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8
KIAA0513 KIAA0513
KIDINS220 kinase D-interacting substrate, 220kDa
KIF1A kinesin family member 1A
KRT33A keratin 33A, type I
LIN7B lin-7 homolog B (C. elegans)
LINS lines homolog (Drosophila)
LRRC37A3 leucine rich repeat containing 37, member A3
LYPD3 LY6/PLAUR domain containing 3
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MED18 mediator complex subunit 18
MEF2D myocyte enhancer factor 2D
MFN2 mitofusin 2
MIIP migration and invasion inhibitory protein
MSL3 male-specific lethal 3 homolog (Drosophila)
MTMR1 myotubularin related protein 1
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NCOA1 nuclear receptor coactivator 1
NEK2 NIMA-related kinase 2
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NR2C1 nuclear receptor subfamily 2, group C, member 1
PADI1 peptidyl arginine deiminase, type I
PHF1 PHD finger protein 1
POLL polymerase (DNA directed), lambda
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRSS53 protease, serine, 53
PTGES prostaglandin E synthase
RCAN1 regulator of calcineurin 1
RDX radixin
RNF216 ring finger protein 216
SAMD9 sterile alpha motif domain containing 9
SLC4A3 solute carrier family 4 (anion exchanger), member 3
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SS18 synovial sarcoma translocation, chromosome 18
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
SUGP1 SURP and G patch domain containing 1
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
SYNJ2 synaptojanin 2
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TIAM1 T-cell lymphoma invasion and metastasis 1
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast)
TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast)
TMEM63A transmembrane protein 63A
TRIM2 tripartite motif containing 2
TTC38 tetratricopeptide repeat domain 38
TTLL3 tubulin tyrosine ligase-like family member 3
TTLL7 tubulin tyrosine ligase-like family member 7
ULK2 unc-51 like autophagy activating kinase 2
UNC5B unc-5 homolog B (C. elegans)
WSB1 WD repeat and SOCS box containing 1
WWOX WW domain containing oxidoreductase
ZC3H7B zinc finger CCCH-type containing 7B
ZFYVE9 zinc finger, FYVE domain containing 9
ZMYM4 zinc finger, MYM-type 4

decreased expression

Symbol Name
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3
ADCY6 adenylate cyclase 6
AGO1 argonaute RISC catalytic component 1
ALG12 ALG12, alpha-1,6-mannosyltransferase
ALPK1 alpha-kinase 1
APEX2 APEX nuclease (apurinic/apyrimidinic endonuclease) 2
ARSJ arylsulfatase family, member J
BANK1 B-cell scaffold protein with ankyrin repeats 1
BRPF1 bromodomain and PHD finger containing, 1
BTBD2 BTB (POZ) domain containing 2
CASZ1 castor zinc finger 1
CCP110 centriolar coiled coil protein 110kDa
CDC25B cell division cycle 25B
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDC73 cell division cycle 73
CEP131 centrosomal protein 131kDa
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
DCLRE1A DNA cross-link repair 1A
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DIXDC1 DIX domain containing 1
DNAL4 dynein, axonemal, light chain 4
DUS2 dihydrouridine synthase 2
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EAF2 ELL associated factor 2
ELF1 E74-like factor 1 (ets domain transcription factor)
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
ETV4 ets variant 4
FAM160B2 family with sequence similarity 160, member B2
FBXO46 F-box protein 46
FBXW12 F-box and WD repeat domain containing 12
FGD1 FYVE, RhoGEF and PH domain containing 1
FKBPL FK506 binding protein like
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GLTSCR1 glioma tumor suppressor candidate region gene 1
GPATCH3 G patch domain containing 3
GUSBP3 glucuronidase, beta pseudogene 3
HAUS6 HAUS augmin-like complex, subunit 6
HIST1H2AG histone cluster 1, H2ag
IL15RA interleukin 15 receptor, alpha
INPP5F inositol polyphosphate-5-phosphatase F
IPP intracisternal A particle-promoted polypeptide
JMJD4 jumonji domain containing 4
KATNBL1 katanin p80 subunit B-like 1
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KIAA0894 KIAA0894 protein
LNPEP leucyl/cystinyl aminopeptidase
LRP5L low density lipoprotein receptor-related protein 5-like
LRRC61 leucine rich repeat containing 61
MAGEA3 melanoma antigen family A3
MAML1 mastermind-like 1 (Drosophila)
MANBA mannosidase, beta A, lysosomal
MANSC1 MANSC domain containing 1
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
NIP7 NIP7, nucleolar pre-rRNA processing protein
NKRF NFKB repressing factor
NOC4L nucleolar complex associated 4 homolog (S. cerevisiae)
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PEX12 peroxisomal biogenesis factor 12
POLH polymerase (DNA directed), eta
POR P450 (cytochrome) oxidoreductase
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PTGES2 prostaglandin E synthase 2
PTGFR prostaglandin F receptor (FP)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK6 protein tyrosine kinase 6
PTPN14 protein tyrosine phosphatase, non-receptor type 14
PTTG3P pituitary tumor-transforming 3, pseudogene
RARS arginyl-tRNA synthetase
RBL1 retinoblastoma-like 1
RCAN3 RCAN family member 3
SCAMP4 secretory carrier membrane protein 4
SCML2 sex comb on midleg-like 2 (Drosophila)
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
STK25 serine/threonine kinase 25
TAGLN transgelin
TBC1D19 TBC1 domain family, member 19
TGDS TDP-glucose 4,6-dehydratase
TH tyrosine hydroxylase
TMBIM1 transmembrane BAX inhibitor motif containing 1
TMEM104 transmembrane protein 104
TOM1 target of myb1 (chicken)
TSC22D4 TSC22 domain family, member 4
USP18 ubiquitin specific peptidase 18
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZC3H12A zinc finger CCCH-type containing 12A
ZC3H3 zinc finger CCCH-type containing 3
ZNF134 zinc finger protein 134
ZNF324 zinc finger protein 324
ZNF668 zinc finger protein 668
ZNF804A zinc finger protein 804A