carbamazepine-5093 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the carbamazepine-5093 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOX3 acyl-CoA oxidase 3, pristanoyl
APAF1 apoptotic peptidase activating factor 1
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3
ASIC1 acid sensing (proton gated) ion channel 1
BIRC7 baculoviral IAP repeat containing 7
BMP1 bone morphogenetic protein 1
BMP4 bone morphogenetic protein 4
BTBD7 BTB (POZ) domain containing 7
C11ORF63 chromosome 11 open reading frame 63
C17ORF70 chromosome 17 open reading frame 70
C22ORF29 chromosome 22 open reading frame 29
C22ORF46 chromosome 22 open reading frame 46
C9ORF9 chromosome 9 open reading frame 9
CA9 carbonic anhydrase IX
CAMKMT calmodulin-lysine N-methyltransferase
CD82 CD82 molecule
CEP68 centrosomal protein 68kDa
CHMP6 charged multivesicular body protein 6
CNN1 calponin 1, basic, smooth muscle
COL8A1 collagen, type VIII, alpha 1
CTC1 CTS telomere maintenance complex component 1
DCTN1 dynactin 1
DDN dendrin
DMTN dematin actin binding protein
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DOK4 docking protein 4
DTX2 deltex 2, E3 ubiquitin ligase
EGFL7 EGF-like-domain, multiple 7
ELK4 ELK4, ETS-domain protein (SRF accessory protein 1)
EXOC6B exocyst complex component 6B
FBXL18 F-box and leucine-rich repeat protein 18
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FLII flightless I homolog (Drosophila)
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GPR161 G protein-coupled receptor 161
GRB7 growth factor receptor-bound protein 7
HDAC7 histone deacetylase 7
HIST1H2BN histone cluster 1, H2bn
HIST1H4C histone cluster 1, H4c
HSF2BP heat shock transcription factor 2 binding protein
ICK intestinal cell (MAK-like) kinase
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
LAT2 linker for activation of T cells family, member 2
LIMD1 LIM domains containing 1
LINC00341 long intergenic non-protein coding RNA 341
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LPCAT4 lysophosphatidylcholine acyltransferase 4
LRP1 low density lipoprotein receptor-related protein 1
LRP2 low density lipoprotein receptor-related protein 2
MAPK7 mitogen-activated protein kinase 7
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MARS methionyl-tRNA synthetase
MIER2 mesoderm induction early response 1, family member 2
MUC7 mucin 7, secreted
MYO1B myosin IB
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NCAPH2 non-SMC condensin II complex, subunit H2
NEK11 NIMA-related kinase 11
NF1 neurofibromin 1
NPPA natriuretic peptide A
ORAI3 ORAI calcium release-activated calcium modulator 3
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PLXND1 plexin D1
POU2F2 POU class 2 homeobox 2
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PTK2B protein tyrosine kinase 2 beta
RAB11FIP3 RAB11 family interacting protein 3 (class II)
RABGAP1 RAB GTPase activating protein 1
RALGPS1 Ral GEF with PH domain and SH3 binding motif 1
RARG retinoic acid receptor, gamma
RGCC regulator of cell cycle
RNF122 ring finger protein 122
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RUNDC3B RUN domain containing 3B
S100A11 S100 calcium binding protein A11
SAP30 Sin3A-associated protein, 30kDa
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SMG6 SMG6 nonsense mediated mRNA decay factor
SND1-IT1 SND1 intronic transcript 1
SNRK SNF related kinase
SYK spleen tyrosine kinase
SYNPO synaptopodin
TADA2A transcriptional adaptor 2A
TLN2 talin 2
TMC6 transmembrane channel-like 6
TMEM231 transmembrane protein 231
TMEM63A transmembrane protein 63A
TMSB15A thymosin beta 15a
TOB2 transducer of ERBB2, 2
TOM1 target of myb1 (chicken)
TRPC1 transient receptor potential cation channel, subfamily C, member 1
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
ZC3H7B zinc finger CCCH-type containing 7B
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF528 zinc finger protein 528
ZNF821 zinc finger protein 821

decreased expression

Symbol Name
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8
ADGRB2 adhesion G protein-coupled receptor B2
ALPK1 alpha-kinase 1
ALS2CL ALS2 C-terminal like
AMT aminomethyltransferase
ANKFY1 ankyrin repeat and FYVE domain containing 1
ARHGAP24 Rho GTPase activating protein 24
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ATAT1 alpha tubulin acetyltransferase 1
C14ORF105 chromosome 14 open reading frame 105
C1R complement component 1, r subcomponent
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CDK3 cyclin-dependent kinase 3
CDON cell adhesion associated, oncogene regulated
CHM choroideremia (Rab escort protein 1)
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CLDN11 claudin 11
CNTNAP3B contactin associated protein-like 3B
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CRYBA2 crystallin, beta A2
CSF1R colony stimulating factor 1 receptor
CUZD1 CUB and zona pellucida-like domains 1
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DET1 de-etiolated homolog 1 (Arabidopsis)
DNAH7 dynein, axonemal, heavy chain 7
EDAR ectodysplasin A receptor
EDIL3 EGF-like repeats and discoidin I-like domains 3
ERCC5 excision repair cross-complementation group 5
EYA3 EYA transcriptional coactivator and phosphatase 3
FBXO2 F-box protein 2
FKBP1B FK506 binding protein 1B, 12.6 kDa
FKBP5 FK506 binding protein 5
GDAP1 ganglioside induced differentiation associated protein 1
GIF gastric intrinsic factor (vitamin B synthesis)
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GSTCD glutathione S-transferase, C-terminal domain containing
GTF2I general transcription factor IIi
HIST1H2BJ histone cluster 1, H2bj
HLA-DMA major histocompatibility complex, class II, DM alpha
ICOS inducible T-cell co-stimulator
IFNA2 interferon, alpha 2
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KLF13 Kruppel-like factor 13
KLHL36 kelch-like family member 36
KRT86 keratin 86, type II
LIMS2 LIM and senescent cell antigen-like domains 2
LOXL3 lysyl oxidase-like 3
LPAR3 lysophosphatidic acid receptor 3
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
LYPD3 LY6/PLAUR domain containing 3
MAGEF1 melanoma antigen family F1
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MNX1 motor neuron and pancreas homeobox 1
MTERF4 mitochondrial transcription termination factor 4
MTHFSD methenyltetrahydrofolate synthetase domain containing
MTMR12 myotubularin related protein 12
MTSS1L metastasis suppressor 1-like
MUC3B mucin 3B, cell surface associated
NCS1 neuronal calcium sensor 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NIPAL2 NIPA-like domain containing 2
NTF3 neurotrophin 3
OR1G1 olfactory receptor, family 1, subfamily G, member 1
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PARP3 poly (ADP-ribose) polymerase family, member 3
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRKG2 protein kinase, cGMP-dependent, type II
R3HCC1L R3H domain and coiled-coil containing 1-like
RAB3A RAB3A, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RBMS3 RNA binding motif, single stranded interacting protein 3
RFPL1S RFPL1 antisense RNA 1
SAYSD1 SAYSVFN motif domain containing 1
SCGB2A2 secretoglobin, family 2A, member 2
SCN1B sodium channel, voltage gated, type I beta subunit
SCUBE3 signal peptide, CUB domain, EGF-like 3
SENP7 SUMO1/sentrin specific peptidase 7
SLC35F6 solute carrier family 35, member F6
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
STK16 serine/threonine kinase 16
SUGCT succinyl-CoA:glutarate-CoA transferase
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TMEM212 transmembrane protein 212
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TTLL1 tubulin tyrosine ligase-like family member 1
ZNF408 zinc finger protein 408
ZNF41 zinc finger protein 41
ZNF446 zinc finger protein 446
ZNF480 zinc finger protein 480
ZNF711 zinc finger protein 711
ZNF747 zinc finger protein 747