carbamazepine-835 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the carbamazepine-835 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADM adrenomedullin
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
ALOX15 arachidonate 15-lipoxygenase
ANXA2P3 annexin A2 pseudogene 3
APLP1 amyloid beta (A4) precursor-like protein 1
ATF3 activating transcription factor 3
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
C17ORF53 chromosome 17 open reading frame 53
C1ORF54 chromosome 1 open reading frame 54
C8ORF4 chromosome 8 open reading frame 4
CACYBP calcyclin binding protein
CALD1 caldesmon 1
CD8A CD8a molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CENPC centromere protein C
CGA glycoprotein hormones, alpha polypeptide
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CRIP1 cysteine-rich protein 1 (intestinal)
CSNK1G1 casein kinase 1, gamma 1
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DHRS2 dehydrogenase/reductase (SDR family) member 2
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DPYSL4 dihydropyrimidinase-like 4
DUSP1 dual specificity phosphatase 1
EGR1 early growth response 1
EPHB6 EPH receptor B6
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
EPOR erythropoietin receptor
ETV5 ets variant 5
FAM149A family with sequence similarity 149, member A
FLT4 fms-related tyrosine kinase 4
FNDC3A fibronectin type III domain containing 3A
FOS FBJ murine osteosarcoma viral oncogene homolog
GADD45A growth arrest and DNA-damage-inducible, alpha
GEM GTP binding protein overexpressed in skeletal muscle
GMIP GEM interacting protein
GOSR2 golgi SNAP receptor complex member 2
GTDC1 glycosyltransferase-like domain containing 1
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIST1H2BN histone cluster 1, H2bn
HSPA1L heat shock 70kDa protein 1-like
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IER5 immediate early response 5
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IRAK3 interleukin-1 receptor-associated kinase 3
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
JUN jun proto-oncogene
KIZ kizuna centrosomal protein
KLHL24 kelch-like family member 24
LAMA4 laminin, alpha 4
LAMP1 lysosomal-associated membrane protein 1
LIMCH1 LIM and calponin homology domains 1
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
METTL7A methyltransferase like 7A
MRPS18C mitochondrial ribosomal protein S18C
PCDH9 protocadherin 9
PLEKHA6 pleckstrin homology domain containing, family A member 6
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A
PRKG2 protein kinase, cGMP-dependent, type II
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RARA retinoic acid receptor, alpha
RBM12B-AS1 RBM12B antisense RNA 1
RGS2 regulator of G-protein signaling 2
SAPCD1 suppressor APC domain containing 1
SCN10A sodium channel, voltage gated, type X alpha subunit
SIPA1 signal-induced proliferation-associated 1
SLC16A4 solute carrier family 16, member 4
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLCO4C1 solute carrier organic anion transporter family, member 4C1
SOGA1 suppressor of glucose, autophagy associated 1
SPRY2 sprouty homolog 2 (Drosophila)
TCHH trichohyalin
TMPRSS4 transmembrane protease, serine 4
TNRC6B trinucleotide repeat containing 6B
TOM1 target of myb1 (chicken)
TPMT thiopurine S-methyltransferase
TPP1 tripeptidyl peptidase I
TRIM21 tripartite motif containing 21
TSPYL2 TSPY-like 2
USP27X ubiquitin specific peptidase 27, X-linked
VDAC3 voltage-dependent anion channel 3
VIPR1 vasoactive intestinal peptide receptor 1
WDFY3 WD repeat and FYVE domain containing 3
WDR59 WD repeat domain 59
ZCCHC14 zinc finger, CCHC domain containing 14
ZNF350 zinc finger protein 350
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ACVR2B activin A receptor, type IIB
ADCY6 adenylate cyclase 6
ANKRD10 ankyrin repeat domain 10
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARL15 ADP-ribosylation factor-like 15
ATAD3A ATPase family, AAA domain containing 3A
BCL9 B-cell CLL/lymphoma 9
C7ORF43 chromosome 7 open reading frame 43
CCNE2 cyclin E2
CD302 CD302 molecule
CISH cytokine inducible SH2-containing protein
CLDN9 claudin 9
COCH cochlin
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DNA2 DNA replication helicase/nuclease 2
DNAL4 dynein, axonemal, light chain 4
DNALI1 dynein, axonemal, light intermediate chain 1
DOLPP1 dolichyldiphosphatase 1
EVPL envoplakin
FA2H fatty acid 2-hydroxylase
FASTKD5 FAST kinase domains 5
GAB2 GRB2-associated binding protein 2
GAS6 growth arrest-specific 6
GATA4 GATA binding protein 4
GOLGA8B golgin A8 family, member B
GSTT1 glutathione S-transferase theta 1
GTPBP3 GTP binding protein 3 (mitochondrial)
HLA-J major histocompatibility complex, class I, J (pseudogene)
IREB2 iron-responsive element binding protein 2
KIAA0125 KIAA0125
KIAA0894 KIAA0894 protein
KLHL2 kelch-like family member 2
LARS leucyl-tRNA synthetase
LHX6 LIM homeobox 6
LOC257152 uncharacterized LOC257152
LZTR1 leucine-zipper-like transcription regulator 1
MANSC1 MANSC domain containing 1
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MSANTD2 Myb/SANT-like DNA-binding domain containing 2
NAT9 N-acetyltransferase 9 (GCN5-related, putative)
NES nestin
NFE2L3 nuclear factor, erythroid 2-like 3
NPY1R neuropeptide Y receptor Y1
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PALM paralemmin
PARD6A par-6 family cell polarity regulator alpha
PARD6B par-6 family cell polarity regulator beta
PCDHB3 protocadherin beta 3
PDZK1 PDZ domain containing 1
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PMP22 peripheral myelin protein 22
POLR3F polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa
POTEKP POTE ankyrin domain family, member K, pseudogene
PRPF38B pre-mRNA processing factor 38B
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PTTG3P pituitary tumor-transforming 3, pseudogene
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RHBG Rh family, B glycoprotein (gene/pseudogene)
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RPAP1 RNA polymerase II associated protein 1
SCN1B sodium channel, voltage gated, type I beta subunit
SECISBP2 SECIS binding protein 2
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SIRT2 sirtuin 2
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SOBP sine oculis binding protein homolog (Drosophila)
SP1 Sp1 transcription factor
SPIDR scaffolding protein involved in DNA repair
SREK1IP1 SREK1-interacting protein 1
SS18L1 synovial sarcoma translocation gene on chromosome 18-like 1
SSFA2 sperm specific antigen 2
STK25 serine/threonine kinase 25
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
SYNJ2BP synaptojanin 2 binding protein
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TAGLN transgelin
TBC1D17 TBC1 domain family, member 17
TESK2 testis-specific kinase 2
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
UNC119 unc-119 homolog (C. elegans)
WDR4 WD repeat domain 4
ZNF250 zinc finger protein 250
ZNF254 zinc finger protein 254
ZNF33B zinc finger protein 33B
ZNF552 zinc finger protein 552
ZNF562 zinc finger protein 562
ZNF692 zinc finger protein 692
ZNF74 zinc finger protein 74
ZNF813 zinc finger protein 813
ZW10 zw10 kinetochore protein