carbarsone-3250 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the carbarsone-3250 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A2M alpha-2-macroglobulin
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
ADD2 adducin 2 (beta)
ADGRL1 adhesion G protein-coupled receptor L1
AKAP7 A kinase (PRKA) anchor protein 7
ARL4D ADP-ribosylation factor-like 4D
ATP11A ATPase, class VI, type 11A
BMP5 bone morphogenetic protein 5
CAMK1D calcium/calmodulin-dependent protein kinase ID
CCDC132 coiled-coil domain containing 132
CCDC186 coiled-coil domain containing 186
CDH10 cadherin 10, type 2 (T2-cadherin)
CENPO centromere protein O
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CNR2 cannabinoid receptor 2 (macrophage)
COL1A1 collagen, type I, alpha 1
COPZ2 coatomer protein complex, subunit zeta 2
CRHR2 corticotropin releasing hormone receptor 2
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
DICER1 dicer 1, ribonuclease type III
DLK2 delta-like 2 homolog (Drosophila)
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DUX1 double homeobox 1
DVL3 dishevelled segment polarity protein 3
EDRF1 erythroid differentiation regulatory factor 1
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
ERN2 endoplasmic reticulum to nucleus signaling 2
ERO1LB ERO1-like beta (S. cerevisiae)
ETV7 ets variant 7
FAS Fas cell surface death receptor
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GK2 glycerol kinase 2
GK3P glycerol kinase 3 pseudogene
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GM2A GM2 ganglioside activator
HIST1H1T histone cluster 1, H1t
HPS1 Hermansky-Pudlak syndrome 1
ICA1 islet cell autoantigen 1, 69kDa
IGFBP3 insulin-like growth factor binding protein 3
IGFBP5 insulin-like growth factor binding protein 5
IGHA1 immunoglobulin heavy constant alpha 1
IL5RA interleukin 5 receptor, alpha
JUN jun proto-oncogene
KIAA0125 KIAA0125
KIF1C kinesin family member 1C
LBP lipopolysaccharide binding protein
LINC00341 long intergenic non-protein coding RNA 341
LMAN1 lectin, mannose-binding, 1
LRP12 low density lipoprotein receptor-related protein 12
LSP1 lymphocyte-specific protein 1
MAPK7 mitogen-activated protein kinase 7
MBNL2 muscleblind-like splicing regulator 2
MERTK MER proto-oncogene, tyrosine kinase
MFAP3 microfibrillar-associated protein 3
MITF microphthalmia-associated transcription factor
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MTSS1 metastasis suppressor 1
MYOF myoferlin
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NOL10 nucleolar protein 10
NOX1 NADPH oxidase 1
NXPE3 neurexophilin and PC-esterase domain family, member 3
NYNRIN NYN domain and retroviral integrase containing
PAIP2B poly(A) binding protein interacting protein 2B
PARD6B par-6 family cell polarity regulator beta
PCDHGA3 protocadherin gamma subfamily A, 3
PDE4C phosphodiesterase 4C, cAMP-specific
PDE5A phosphodiesterase 5A, cGMP-specific
PLEK pleckstrin
PLIN2 perilipin 2
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PRIM2 primase, DNA, polypeptide 2 (58kDa)
PRX periaxin
PSG9 pregnancy specific beta-1-glycoprotein 9
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
RNF126P1 ring finger protein 126 pseudogene 1
SCAND2P SCAN domain containing 2 pseudogene
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOS2 son of sevenless homolog 2 (Drosophila)
SPHK2 sphingosine kinase 2
TDRD12 tudor domain containing 12
TENM4 teneurin transmembrane protein 4
THRB thyroid hormone receptor, beta
TLK1 tousled-like kinase 1
TMOD1 tropomodulin 1
TMPO thymopoietin
TMPRSS15 transmembrane protease, serine 15
TRIB2 tribbles pseudokinase 2
TSNAXIP1 translin-associated factor X interacting protein 1
UBTD1 ubiquitin domain containing 1
YPEL1 yippee-like 1 (Drosophila)
ZFX zinc finger protein, X-linked
ZNF362 zinc finger protein 362
ZNF428 zinc finger protein 428

decreased expression

Symbol Name
ABHD3 abhydrolase domain containing 3
ABHD4 abhydrolase domain containing 4
ACSF2 acyl-CoA synthetase family member 2
AGBL5 ATP/GTP binding protein-like 5
BAHD1 bromo adjacent homology domain containing 1
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
C17ORF70 chromosome 17 open reading frame 70
CA11 carbonic anhydrase XI
CCDC176 coiled-coil domain containing 176
CCNL2 cyclin L2
CCNO cyclin O
CDK5 cyclin-dependent kinase 5
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CGA glycoprotein hormones, alpha polypeptide
CHKB choline kinase beta
CISH cytokine inducible SH2-containing protein
COBL cordon-bleu WH2 repeat protein
COL4A5 collagen, type IV, alpha 5
COPS7B COP9 signalosome subunit 7B
CSTA cystatin A (stefin A)
CUEDC1 CUE domain containing 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
EFNA3 ephrin-A3
EHMT1 euchromatic histone-lysine N-methyltransferase 1
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
EPHA2 EPH receptor A2
F8 coagulation factor VIII, procoagulant component
FAM160B2 family with sequence similarity 160, member B2
FBXL6 F-box and leucine-rich repeat protein 6
FXR2 fragile X mental retardation, autosomal homolog 2
GAS6 growth arrest-specific 6
GLI3 GLI family zinc finger 3
GLS2 glutaminase 2 (liver, mitochondrial)
HDAC11 histone deacetylase 11
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
HIST1H4F histone cluster 1, H4f
HOXC11 homeobox C11
HPS6 Hermansky-Pudlak syndrome 6
IFT81 intraflagellar transport 81
IL4R interleukin 4 receptor
INPPL1 inositol polyphosphate phosphatase-like 1
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
KCTD15 potassium channel tetramerization domain containing 15
KLF10 Kruppel-like factor 10
LAMA5 laminin, alpha 5
MAP1S microtubule-associated protein 1S
MBTD1 mbt domain containing 1
MTCL1 microtubule crosslinking factor 1
MTERF4 mitochondrial transcription termination factor 4
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
MYL5 myosin, light chain 5, regulatory
NPIPB15 nuclear pore complex interacting protein family, member B15
NPM3 nucleophosmin/nucleoplasmin 3
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor
PAQR4 progestin and adipoQ receptor family member IV
PCDHB13 protocadherin beta 13
PIEZO1 piezo-type mechanosensitive ion channel component 1
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
PRSS22 protease, serine, 22
PTBP2 polypyrimidine tract binding protein 2
R3HCC1L R3H domain and coiled-coil containing 1-like
RAB4B RAB4B, member RAS oncogene family
RBM42 RNA binding motif protein 42
RHOC ras homolog family member C
RNF122 ring finger protein 122
RNF123 ring finger protein 123
RNF31 ring finger protein 31
SCAI suppressor of cancer cell invasion
SECTM1 secreted and transmembrane 1
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SIK1 salt-inducible kinase 1
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SNAI2 snail family zinc finger 2
SND1 staphylococcal nuclease and tudor domain containing 1
SPIDR scaffolding protein involved in DNA repair
SUN2 Sad1 and UNC84 domain containing 2
SYT17 synaptotagmin XVII
TMEM180 transmembrane protein 180
TMEM254 transmembrane protein 254
TMUB2 transmembrane and ubiquitin-like domain containing 2
TRABD TraB domain containing
TRAPPC11 trafficking protein particle complex 11
TTC13 tetratricopeptide repeat domain 13
TUBA3D tubulin, alpha 3d
UBE2L6 ubiquitin-conjugating enzyme E2L 6
UQCC1 ubiquinol-cytochrome c reductase complex assembly factor 1
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
VWA1 von Willebrand factor A domain containing 1
WASF1 WAS protein family, member 1
WRAP73 WD repeat containing, antisense to TP73
ZNF282 zinc finger protein 282
ZNF552 zinc finger protein 552
ZNF696 zinc finger protein 696