carbarsone-3991 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the carbarsone-3991 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ADAM22 ADAM metallopeptidase domain 22
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
AGTR1 angiotensin II receptor, type 1
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ALDOB aldolase B, fructose-bisphosphate
BBC3 BCL2 binding component 3
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C1ORF105 chromosome 1 open reading frame 105
CASP8 caspase 8, apoptosis-related cysteine peptidase
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CBS cystathionine-beta-synthase
CCL27 chemokine (C-C motif) ligand 27
CD58 CD58 molecule
CDC42 cell division cycle 42
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CNTNAP2 contactin associated protein-like 2
COL4A6 collagen, type IV, alpha 6
COMMD4 COMM domain containing 4
CROCCP3 ciliary rootlet coiled-coil, rootletin pseudogene 3
CTSS cathepsin S
CUBN cubilin (intrinsic factor-cobalamin receptor)
DIAPH2-AS1 DIAPH2 antisense RNA 1
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DOCK10 dedicator of cytokinesis 10
DST dystonin
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene
EXOC7 exocyst complex component 7
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FN1 fibronectin 1
FRK fyn-related Src family tyrosine kinase
GRIK2 glutamate receptor, ionotropic, kainate 2
HBS1L HBS1-like translational GTPase
HIST1H4C histone cluster 1, H4c
ICOSLG inducible T-cell co-stimulator ligand
IL12B interleukin 12B
IL36A interleukin 36, alpha
IQCK IQ motif containing K
KDM5B lysine (K)-specific demethylase 5B
KHK ketohexokinase (fructokinase)
KIAA1109 KIAA1109
KRTAP9-9 keratin associated protein 9-9
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LPP LIM domain containing preferred translocation partner in lipoma
MAN2A2 mannosidase, alpha, class 2A, member 2
MOG myelin oligodendrocyte glycoprotein
MSTN myostatin
MYH2 myosin, heavy chain 2, skeletal muscle, adult
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NRN1 neuritin 1
NRP2 neuropilin 2
NSUN6 NOP2/Sun domain family, member 6
NUDT7 nudix (nucleoside diphosphate linked moiety X)-type motif 7
OBSL1 obscurin-like 1
OMG oligodendrocyte myelin glycoprotein
PCSK5 proprotein convertase subtilisin/kexin type 5
PDGFA platelet-derived growth factor alpha polypeptide
PDIA2 protein disulfide isomerase family A, member 2
PGM5 phosphoglucomutase 5
PKD2L2 polycystic kidney disease 2-like 2
PLSCR2 phospholipid scramblase 2
PLXNA2 plexin A2
PPARD peroxisome proliferator-activated receptor delta
PPP1R3D protein phosphatase 1, regulatory subunit 3D
PPP4R4 protein phosphatase 4, regulatory subunit 4
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRKCI protein kinase C, iota
PRKG1 protein kinase, cGMP-dependent, type I
PTBP3 polypyrimidine tract binding protein 3
PTGDS prostaglandin D2 synthase 21kDa (brain)
RAB6B RAB6B, member RAS oncogene family
RBM26 RNA binding motif protein 26
RHOBTB3 Rho-related BTB domain containing 3
RIBC2 RIB43A domain with coiled-coils 2
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
SGSM3 small G protein signaling modulator 3
SH3BP1 SH3-domain binding protein 1
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SMAD4 SMAD family member 4
STATH statherin
SUSD5 sushi domain containing 5
SYMPK symplekin
THAP9 THAP domain containing 9
THBD thrombomodulin
THOC5 THO complex 5
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast)
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TPTE transmembrane phosphatase with tensin homology
TRA2A transformer 2 alpha homolog (Drosophila)
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae)
TSPAN8 tetraspanin 8
TUBA4B tubulin, alpha 4b
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
VGF VGF nerve growth factor inducible
VILL villin-like
WNK1 WNK lysine deficient protein kinase 1
ZNF639 zinc finger protein 639

decreased expression

Symbol Name
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8
ABHD4 abhydrolase domain containing 4
ADGRE2 adhesion G protein-coupled receptor E2
AGO4 argonaute RISC catalytic component 4
ANKFY1 ankyrin repeat and FYVE domain containing 1
ARC activity-regulated cytoskeleton-associated protein
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ARPIN actin-related protein 2/3 complex inhibitor
B9D2 B9 protein domain 2
C17ORF53 chromosome 17 open reading frame 53
C1ORF21 chromosome 1 open reading frame 21
CAPN15 calpain 15
CASP5 caspase 5, apoptosis-related cysteine peptidase
CBX4 chromobox homolog 4
CCNO cyclin O
CIDEB cell death-inducing DFFA-like effector b
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CNIH3 cornichon family AMPA receptor auxiliary protein 3
CRMP1 collapsin response mediator protein 1
CTSK cathepsin K
DEAF1 DEAF1 transcription factor
DNAL4 dynein, axonemal, light chain 4
DNM3 dynamin 3
EFNA3 ephrin-A3
EPN1 epsin 1
EYA3 EYA transcriptional coactivator and phosphatase 3
FRMPD1 FERM and PDZ domain containing 1
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GPR19 G protein-coupled receptor 19
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GTPBP2 GTP binding protein 2
HDAC7 histone deacetylase 7
IFNA17 interferon, alpha 17
IGFLR1 IGF-like family receptor 1
IL12RB1 interleukin 12 receptor, beta 1
IL17RA interleukin 17 receptor A
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
ISYNA1 inositol-3-phosphate synthase 1
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGB7 integrin, beta 7
JMJD4 jumonji domain containing 4
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12
KDM8 lysine (K)-specific demethylase 8
KRT33A keratin 33A, type I
KRT8P12 keratin 8 pseudogene 12
LIME1 Lck interacting transmembrane adaptor 1
LMTK1 lemur tail kinase 1
LPCAT3 lysophosphatidylcholine acyltransferase 3
LRRK1 leucine-rich repeat kinase 1
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MMP10 matrix metallopeptidase 10
MNMIP1 manchette microtubule inner protein 1
MYO1F myosin IF
NIPAL2 NIPA-like domain containing 2
NOL12 nucleolar protein 12
NUBP2 nucleotide binding protein 2
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
PADI1 peptidyl arginine deiminase, type I
PARM1 prostate androgen-regulated mucin-like protein 1
PC pyruvate carboxylase
PID1 phosphotyrosine interaction domain containing 1
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLBD1 phospholipase B domain containing 1
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLD3 phospholipase D family, member 3
PLEKHO2 pleckstrin homology domain containing, family O member 2
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PRR15L proline rich 15-like
PRR4 proline rich 4 (lacrimal)
PSORS1C1 psoriasis susceptibility 1 candidate 1
PTK6 protein tyrosine kinase 6
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B)
RIMBP2 RIMS binding protein 2
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
SCG2 secretogranin II
SECISBP2 SECIS binding protein 2
SLAMF7 SLAM family member 7
SLC16A6 solute carrier family 16, member 6
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC46A3 solute carrier family 46, member 3
SLITRK5 SLIT and NTRK-like family, member 5
SPEG SPEG complex locus
SSTR4 somatostatin receptor 4
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TDRD7 tudor domain containing 7
TENM4 teneurin transmembrane protein 4
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
WNT1 wingless-type MMTV integration site family, member 1
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF667 zinc finger protein 667