carbarsone-4110 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the carbarsone-4110 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4
AKT2 v-akt murine thymoma viral oncogene homolog 2
ANKRD7 ankyrin repeat domain 7
AOX1 aldehyde oxidase 1
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATHL1 ATH1, acid trehalase-like 1 (yeast)
BANK1 B-cell scaffold protein with ankyrin repeats 1
BCAP29 B-cell receptor-associated protein 29
BMP1 bone morphogenetic protein 1
C14ORF105 chromosome 14 open reading frame 105
C8A complement component 8, alpha polypeptide
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CCDC57 coiled-coil domain containing 57
CDO1 cysteine dioxygenase type 1
CIB2 calcium and integrin binding family member 2
CIITA class II, major histocompatibility complex, transactivator
CLDN11 claudin 11
COL17A1 collagen, type XVII, alpha 1
DCTN1 dynactin 1
DRICH1 aspartate-rich 1
EFCAB11 EF-hand calcium binding domain 11
ETV7 ets variant 7
FABP7 fatty acid binding protein 7, brain
FASLG Fas ligand (TNF superfamily, member 6)
GAB1 GRB2-associated binding protein 1
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GGT1 gamma-glutamyltransferase 1
GJA4 gap junction protein, alpha 4, 37kDa
GJA8 gap junction protein, alpha 8, 50kDa
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GPATCH4 G patch domain containing 4
GPR137 G protein-coupled receptor 137
GPR143 G protein-coupled receptor 143
GREB1L growth regulation by estrogen in breast cancer-like
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HAB1 B1 for mucin
HPX hemopexin
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IL37 interleukin 37
IPW imprinted in Prader-Willi syndrome (non-protein coding)
ITGA7 integrin, alpha 7
LAMB4 laminin, beta 4
LIMCH1 LIM and calponin homology domains 1
LMO1 LIM domain only 1 (rhombotin 1)
LOC157562 uncharacterized LOC157562
MAL mal, T-cell differentiation protein
MBP myelin basic protein
MMP17 matrix metallopeptidase 17 (membrane-inserted)
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
NBL1 neuroblastoma 1, DAN family BMP antagonist
NPFF neuropeptide FF-amide peptide precursor
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae)
NRXN1 neurexin 1
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
PAX6 paired box 6
PCDHGA3 protocadherin gamma subfamily A, 3
PKP2 plakophilin 2
PLAC4 placenta-specific 4
PPP5C protein phosphatase 5, catalytic subunit
PRKG2 protein kinase, cGMP-dependent, type II
PRPH2 peripherin 2 (retinal degeneration, slow)
RAB3B RAB3B, member RAS oncogene family
RAB6A RAB6A, member RAS oncogene family
RAD54L2 RAD54-like 2 (S. cerevisiae)
REPS1 RALBP1 associated Eps domain containing 1
RGS14 regulator of G-protein signaling 14
RPS4Y1 ribosomal protein S4, Y-linked 1
RUNX1 runt-related transcription factor 1
SAG S-antigen; retina and pineal gland (arrestin)
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SIT1 signaling threshold regulating transmembrane adaptor 1
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC35E2 solute carrier family 35, member E2
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SP100 SP100 nuclear antigen
SPAG8 sperm associated antigen 8
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SYNE1 spectrin repeat containing, nuclear envelope 1
TENM1 teneurin transmembrane protein 1
TEX13B testis expressed 13B
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
THRB thyroid hormone receptor, beta
TP63 tumor protein p63
TRIM15 tripartite motif containing 15
TUBA3C tubulin, alpha 3c
UBXN1 UBX domain protein 1
USP20 ubiquitin specific peptidase 20
USP29 ubiquitin specific peptidase 29
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae)
VWA5A von Willebrand factor A domain containing 5A
WNT16 wingless-type MMTV integration site family, member 16
XIST X inactive specific transcript (non-protein coding)
ZC3H7B zinc finger CCCH-type containing 7B
ZNF609 zinc finger protein 609

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ADAT1 adenosine deaminase, tRNA-specific 1
ALOX15 arachidonate 15-lipoxygenase
C21ORF91 chromosome 21 open reading frame 91
CCDC85C coiled-coil domain containing 85C
CCNL2 cyclin L2
CD82 CD82 molecule
CES3 carboxylesterase 3
CHKB choline kinase beta
CLCN5 chloride channel, voltage-sensitive 5
CLSTN2 calsyntenin 2
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DIXDC1 DIX domain containing 1
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
ERCC4 excision repair cross-complementation group 4
ESRP2 epithelial splicing regulatory protein 2
FAM46C family with sequence similarity 46, member C
FKBP14 FK506 binding protein 14, 22 kDa
FRK fyn-related Src family tyrosine kinase
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GINS4 GINS complex subunit 4 (Sld5 homolog)
GLI3 GLI family zinc finger 3
GMEB1 glucocorticoid modulatory element binding protein 1
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H1E histone cluster 1, H1e
HMOX1 heme oxygenase 1
HOXC10 homeobox C10
HOXC8 homeobox C8
IFI6 interferon, alpha-inducible protein 6
IPO8 importin 8
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KLF3 Kruppel-like factor 3 (basic)
LINC00339 long intergenic non-protein coding RNA 339
LPPR1 lipid phosphate phosphatase-related protein type 1
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MBTPS2 membrane-bound transcription factor peptidase, site 2
MFSD11 major facilitator superfamily domain containing 11
MVP major vault protein
NECAB3 N-terminal EF-hand calcium binding protein 3
OSGIN1 oxidative stress induced growth inhibitor 1
PAIP2B poly(A) binding protein interacting protein 2B
PARP16 poly (ADP-ribose) polymerase family, member 16
PCDHGB5 protocadherin gamma subfamily B, 5
PGPEP1 pyroglutamyl-peptidase I
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLD2 phospholipase D2
POLL polymerase (DNA directed), lambda
PRR14L proline rich 14-like
PTPN14 protein tyrosine phosphatase, non-receptor type 14
RAB23 RAB23, member RAS oncogene family
RBBP5 retinoblastoma binding protein 5
RFWD3 ring finger and WD repeat domain 3
RFX7 regulatory factor X, 7
RNF122 ring finger protein 122
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
S100A4 S100 calcium binding protein A4
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SNX16 sorting nexin 16
SP1 Sp1 transcription factor
SPRYD7 SPRY domain containing 7
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
STEAP1 six transmembrane epithelial antigen of the prostate 1
STRN striatin, calmodulin binding protein
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TAOK1 TAO kinase 1
TEP1 telomerase-associated protein 1
TET3 tet methylcytosine dioxygenase 3
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TIPRL TOR signaling pathway regulator
TLR5 toll-like receptor 5
TMEM104 transmembrane protein 104
TMEM120B transmembrane protein 120B
TRIM16 tripartite motif containing 16
TRIM25 tripartite motif containing 25
TRIP10 thyroid hormone receptor interactor 10
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae)
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
VGF VGF nerve growth factor inducible
WDR4 WD repeat domain 4
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZNF160 zinc finger protein 160
ZNF286A zinc finger protein 286A
ZNF606 zinc finger protein 606
ZNF652 zinc finger protein 652
ZNF721 zinc finger protein 721
ZNF862 zinc finger protein 862