| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the carbenoxolone-4093 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM22 | ADAM metallopeptidase domain 22 |
| ADAP1 | ArfGAP with dual PH domains 1 |
| AGER | advanced glycosylation end product-specific receptor |
| AIM2 | absent in melanoma 2 |
| AOC3 | amine oxidase, copper containing 3 |
| AQP4 | aquaporin 4 |
| ARMCX1 | armadillo repeat containing, X-linked 1 |
| ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
| BCAM | basal cell adhesion molecule (Lutheran blood group) |
| C7ORF26 | chromosome 7 open reading frame 26 |
| CA9 | carbonic anhydrase IX |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 |
| CCR7 | chemokine (C-C motif) receptor 7 |
| CD33 | CD33 molecule |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CHD5 | chromodomain helicase DNA binding protein 5 |
| CHRNA1 | cholinergic receptor, nicotinic, alpha 1 (muscle) |
| COBL | cordon-bleu WH2 repeat protein |
| COL19A1 | collagen, type XIX, alpha 1 |
| CPZ | carboxypeptidase Z |
| DHX34 | DEAH (Asp-Glu-Ala-His) box polypeptide 34 |
| EDA | ectodysplasin A |
| EFS | embryonal Fyn-associated substrate |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 |
| ERP44 | endoplasmic reticulum protein 44 |
| ESR2 | estrogen receptor 2 (ER beta) |
| ESRRG | estrogen-related receptor gamma |
| FOXP3 | forkhead box P3 |
| FRMD8 | FERM domain containing 8 |
| FUT3 | fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) |
| FZD10 | frizzled class receptor 10 |
| GABRQ | gamma-aminobutyric acid (GABA) A receptor, theta |
| HBB | hemoglobin, beta |
| HIST1H2BM | histone cluster 1, H2bm |
| HOXD13 | homeobox D13 |
| HPSE2 | heparanase 2 (inactive) |
| HTR5A | 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) |
| IHH | indian hedgehog |
| INS | insulin |
| ITGB8 | integrin, beta 8 |
| KLK12 | kallikrein-related peptidase 12 |
| KRT16 | keratin 16, type I |
| KRT24 | keratin 24, type I |
| LAMB4 | laminin, beta 4 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LSP1 | lymphocyte-specific protein 1 |
| MAGEB2 | melanoma antigen family B2 |
| MEGF6 | multiple EGF-like-domains 6 |
| MSX2 | msh homeobox 2 |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| MTMR7 | myotubularin related protein 7 |
| MYBPC3 | myosin binding protein C, cardiac |
| MYH14 | myosin, heavy chain 14, non-muscle |
| MYH2 | myosin, heavy chain 2, skeletal muscle, adult |
| N4BP2L2-IT2 | N4BPL2 intronic transcript 2 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 |
| NOX3 | NADPH oxidase 3 |
| NPC1 | Niemann-Pick disease, type C1 |
| NR2E3 | nuclear receptor subfamily 2, group E, member 3 |
| NTM | neurotrimin |
| OPRM1 | opioid receptor, mu 1 |
| P2RY4 | pyrimidinergic receptor P2Y, G-protein coupled, 4 |
| PEX16 | peroxisomal biogenesis factor 16 |
| PHOX2A | paired-like homeobox 2a |
| PICALM | phosphatidylinositol binding clathrin assembly protein |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PKLR | pyruvate kinase, liver and RBC |
| PMFBP1 | polyamine modulated factor 1 binding protein 1 |
| PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PRKAR1B | protein kinase, cAMP-dependent, regulatory, type I, beta |
| PROX1 | prospero homeobox 1 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) |
| RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) |
| RPRM | reprimo, TP53 dependent G2 arrest mediator candidate |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SCAPER | S-phase cyclin A-associated protein in the ER |
| SCN2B | sodium channel, voltage gated, type II beta subunit |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
| SIGLEC6 | sialic acid binding Ig-like lectin 6 |
| SLA | Src-like-adaptor |
| SLAMF7 | SLAM family member 7 |
| SOX10 | SRY (sex determining region Y)-box 10 |
| SOX5 | SRY (sex determining region Y)-box 5 |
| SPICE1 | spindle and centriole associated protein 1 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) |
| SYNPO2L | synaptopodin 2-like |
| TBL1Y | transducin (beta)-like 1, Y-linked |
| TLX2 | T-cell leukemia homeobox 2 |
| TM4SF20 | transmembrane 4 L six family member 20 |
| TMLHE | trimethyllysine hydroxylase, epsilon |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase |
| TRPC7 | transient receptor potential cation channel, subfamily C, member 7 |
| VAX2 | ventral anterior homeobox 2 |
| VWA5A | von Willebrand factor A domain containing 5A |
| YIF1B | Yip1 interacting factor homolog B (S. cerevisiae) |
| Symbol | Name |
|---|---|
| AMDHD2 | amidohydrolase domain containing 2 |
| ARHGAP10 | Rho GTPase activating protein 10 |
| ARHGAP22 | Rho GTPase activating protein 22 |
| ASTN1 | astrotactin 1 |
| ATG10 | autophagy related 10 |
| BDKRB1 | bradykinin receptor B1 |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C17ORF70 | chromosome 17 open reading frame 70 |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CHRNA9 | cholinergic receptor, nicotinic, alpha 9 (neuronal) |
| CLIC3 | chloride intracellular channel 3 |
| CNTNAP3B | contactin associated protein-like 3B |
| CYB5R2 | cytochrome b5 reductase 2 |
| DEPTOR | DEP domain containing MTOR-interacting protein |
| DLK2 | delta-like 2 homolog (Drosophila) |
| DLL3 | delta-like 3 (Drosophila) |
| EDN1 | endothelin 1 |
| EFNA3 | ephrin-A3 |
| EPPK1 | epiplakin 1 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| EXO5 | exonuclease 5 |
| FBXO31 | F-box protein 31 |
| FGL1 | fibrinogen-like 1 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FKBP5 | FK506 binding protein 5 |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 |
| GEMIN8 | gem (nuclear organelle) associated protein 8 |
| GMPR | guanosine monophosphate reductase |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| GPR19 | G protein-coupled receptor 19 |
| GRM4 | glutamate receptor, metabotropic 4 |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| HIRA | histone cell cycle regulator |
| HIST1H2BN | histone cluster 1, H2bn |
| HOXA6 | homeobox A6 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IL15RA | interleukin 15 receptor, alpha |
| IL33 | interleukin 33 |
| INO80D | INO80 complex subunit D |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KIFC1 | kinesin family member C1 |
| LMTK1 | lemur tail kinase 1 |
| LOC257152 | uncharacterized LOC257152 |
| LOC390998 | ribosomal protein L10 pseudogene |
| LRRC2 | leucine rich repeat containing 2 |
| LTC4S | leukotriene C4 synthase |
| LUM | lumican |
| MTSS1L | metastasis suppressor 1-like |
| NGF | nerve growth factor (beta polypeptide) |
| NOL10 | nucleolar protein 10 |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| OR12D2 | olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| OXCT2 | 3-oxoacid CoA transferase 2 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PALMD | palmdelphin |
| PLA2G1B | phospholipase A2, group IB (pancreas) |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PODXL2 | podocalyxin-like 2 |
| PRPH | peripherin |
| PRSS12 | protease, serine, 12 (neurotrypsin, motopsin) |
| PRSS53 | protease, serine, 53 |
| PVRL2 | poliovirus receptor-related 2 (herpesvirus entry mediator B) |
| QSER1 | glutamine and serine rich 1 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RFPL3 | ret finger protein-like 3 |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
| RUSC2 | RUN and SH3 domain containing 2 |
| S1PR1 | sphingosine-1-phosphate receptor 1 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SELL | selectin L |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SOD3 | superoxide dismutase 3, extracellular |
| SSTR4 | somatostatin receptor 4 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| SYNPO | synaptopodin |
| TFDP3 | transcription factor Dp family, member 3 |
| THBS3 | thrombospondin 3 |
| THSD4 | thrombospondin, type I, domain containing 4 |
| TMEM212 | transmembrane protein 212 |
| TRAC | T cell receptor alpha constant |
| TSGA10 | testis specific, 10 |
| TSPAN2 | tetraspanin 2 |
| ZNF219 | zinc finger protein 219 |
| ZNF268 | zinc finger protein 268 |
| ZNF280A | zinc finger protein 280A |
| ZNF415 | zinc finger protein 415 |
| ZNF549 | zinc finger protein 549 |
| ZNF76 | zinc finger protein 76 |
| ZNF778 | zinc finger protein 778 |
