carbinoxamine-3466 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the carbinoxamine-3466 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
ACTG2 actin, gamma 2, smooth muscle, enteric
ADARB1 adenosine deaminase, RNA-specific, B1
AKT2 v-akt murine thymoma viral oncogene homolog 2
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARID4B AT rich interactive domain 4B (RBP1-like)
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide
CARTPT CART prepropeptide
CD1E CD1e molecule
CD24 CD24 molecule
CFLAR CASP8 and FADD-like apoptosis regulator
CHML choroideremia-like (Rab escort protein 2)
CIC capicua transcriptional repressor
CISH cytokine inducible SH2-containing protein
COL5A1 collagen, type V, alpha 1
COL6A1 collagen, type VI, alpha 1
COL9A2 collagen, type IX, alpha 2
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
E2F4 E2F transcription factor 4, p107/p130-binding
ECE1 endothelin converting enzyme 1
EMID1 EMI domain containing 1
EWSR1 EWS RNA-binding protein 1
EXOC7 exocyst complex component 7
FH fumarate hydratase
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5
GLRX3 glutaredoxin 3
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
GPER1 G protein-coupled estrogen receptor 1
GRK5 G protein-coupled receptor kinase 5
GYG2 glycogenin 2
HFE hemochromatosis
HRK harakiri, BCL2 interacting protein
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KCTD13 potassium channel tetramerization domain containing 13
KRT17 keratin 17, type I
LDB3 LIM domain binding 3
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
MTA2 metastasis associated 1 family, member 2
MYOF myoferlin
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NMT1 N-myristoyltransferase 1
NOL10 nucleolar protein 10
NOL12 nucleolar protein 12
NRSN2 neurensin 2
OSGIN1 oxidative stress induced growth inhibitor 1
PCDHA6 protocadherin alpha 6
PDE4DIP phosphodiesterase 4D interacting protein
PHF8 PHD finger protein 8
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLCB2 phospholipase C, beta 2
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
POMT2 protein-O-mannosyltransferase 2
PP14571 uncharacterized LOC100130449
PPARG peroxisome proliferator-activated receptor gamma
PTDSS2 phosphatidylserine synthase 2
RAD52 RAD52 homolog (S. cerevisiae)
RALGPS1 Ral GEF with PH domain and SH3 binding motif 1
RARA retinoic acid receptor, alpha
RNF122 ring finger protein 122
SAG S-antigen; retina and pineal gland (arrestin)
SAMD4A sterile alpha motif domain containing 4A
SBNO1 strawberry notch homolog 1 (Drosophila)
SBNO2 strawberry notch homolog 2 (Drosophila)
SCAMP1 secretory carrier membrane protein 1
SCAND2P SCAN domain containing 2 pseudogene
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SH2B1 SH2B adaptor protein 1
SH3BP2 SH3-domain binding protein 2
SIDT2 SID1 transmembrane family, member 2
SIRT4 sirtuin 4
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SRI sorcin
SSBP3 single stranded DNA binding protein 3
STARD3 StAR-related lipid transfer (START) domain containing 3
STC1 stanniocalcin 1
STS steroid sulfatase (microsomal), isozyme S
TIMP3 TIMP metallopeptidase inhibitor 3
TMC6 transmembrane channel-like 6
TMEM63A transmembrane protein 63A
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TRAF2 TNF receptor-associated factor 2
TRIM36 tripartite motif containing 36
UTRN utrophin
ZFP36L2 ZFP36 ring finger protein-like 2
ZHX3 zinc fingers and homeoboxes 3
ZNF350 zinc finger protein 350

decreased expression

Symbol Name
AKAP12 A kinase (PRKA) anchor protein 12
ANKFY1 ankyrin repeat and FYVE domain containing 1
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARL15 ADP-ribosylation factor-like 15
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BGLAP bone gamma-carboxyglutamate (gla) protein
BPGM 2,3-bisphosphoglycerate mutase
BRPF1 bromodomain and PHD finger containing, 1
C11ORF80 chromosome 11 open reading frame 80
C1ORF216 chromosome 1 open reading frame 216
CASZ1 castor zinc finger 1
CCDC85C coiled-coil domain containing 85C
CD302 CD302 molecule
CDC37L1 cell division cycle 37-like 1
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLDN15 claudin 15
CLSPN claspin
CORT cortistatin
CRYBB2P1 crystallin, beta B2 pseudogene 1
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
DGKD diacylglycerol kinase, delta 130kDa
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EFTUD1 elongation factor Tu GTP binding domain containing 1
ELOVL4 ELOVL fatty acid elongase 4
EPB41L5 erythrocyte membrane protein band 4.1 like 5
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FAM155B family with sequence similarity 155, member B
FAM169A family with sequence similarity 169, member A
FAM53B family with sequence similarity 53, member B
FBXL2 F-box and leucine-rich repeat protein 2
FEM1C fem-1 homolog c (C. elegans)
GALK1 galactokinase 1
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GPATCH3 G patch domain containing 3
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
HIST1H3B histone cluster 1, H3b
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
IPO8 importin 8
KIF13B kinesin family member 13B
LIG3 ligase III, DNA, ATP-dependent
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LPCAT3 lysophosphatidylcholine acyltransferase 3
LPIN2 lipin 2
LRRC49 leucine rich repeat containing 49
MAST3 microtubule associated serine/threonine kinase 3
MBTD1 mbt domain containing 1
MFSD11 major facilitator superfamily domain containing 11
MKS1 Meckel syndrome, type 1
MRPL52 mitochondrial ribosomal protein L52
NDE1 nudE neurodevelopment protein 1
NIPAL2 NIPA-like domain containing 2
P3H1 prolyl 3-hydroxylase 1
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLEKHO1 pleckstrin homology domain containing, family O member 1
PROS1 protein S (alpha)
RASAL1 RAS protein activator like 1 (GAP1 like)
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
RWDD3 RWD domain containing 3
SEZ6L2 seizure related 6 homolog (mouse)-like 2
SHFM1 split hand/foot malformation (ectrodactyly) type 1
SIRT6 sirtuin 6
SLC12A8 solute carrier family 12, member 8
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SMYD5 SMYD family member 5
SRD5A3 steroid 5 alpha-reductase 3
SREK1IP1 SREK1-interacting protein 1
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STK25 serine/threonine kinase 25
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TDRD1 tudor domain containing 1
TESC tescalcin
THAP7 THAP domain containing 7
THOP1 thimet oligopeptidase 1
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TOLLIP toll interacting protein
TRIM66 tripartite motif containing 66
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae)
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TUBA3C tubulin, alpha 3c
UBQLN4 ubiquilin 4
USP20 ubiquitin specific peptidase 20
USP27X ubiquitin specific peptidase 27, X-linked
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WDR60 WD repeat domain 60
WDR76 WD repeat domain 76
ZNF211 zinc finger protein 211
ZNF282 zinc finger protein 282
ZNF33B zinc finger protein 33B
ZNF768 zinc finger protein 768
ZSCAN5A zinc finger and SCAN domain containing 5A