carboxy-lyase activity Gene Set

Dataset GO Molecular Function Annotations 2025
Category structural or functional annotations
Type molecular function
Description Catalysis of the nonhydrolytic addition or removal of a carboxyl group to or from a compound. (Gene Ontology, GO_0016831)
External Link http://amigo.geneontology.org/amigo/term/GO:0016831
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Genes

29 genes performing the carboxy-lyase activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

Symbol Name
ACMSD aminocarboxymuconate semialdehyde decarboxylase
ACOD1 aconitate decarboxylase 1
AZIN1 antizyme inhibitor 1
AZIN2 antizyme inhibitor 2
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide
COQ4 coenzyme Q4
CSAD cysteine sulfinic acid decarboxylase
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
DDTL D-dopachrome tautomerase-like
ECHDC1 ethylmalonyl-CoA decarboxylase 1
FAHD1 fumarylacetoacetate hydrolase domain containing 1
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GADL1 glutamate decarboxylase-like 1
GGCX gamma-glutamyl carboxylase
HECA headcase homolog (Drosophila)
MLYCD malonyl-CoA decarboxylase
MVD mevalonate (diphospho) decarboxylase
NPR2 natriuretic peptide receptor 2
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PCDHB16 protocadherin beta 16
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PISD phosphatidylserine decarboxylase
PPCDC phosphopantothenoylcysteine decarboxylase
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
UMPS uridine monophosphate synthetase
URAD ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase
UROD uroporphyrinogen decarboxylase
UXS1 UDP-glucuronate decarboxylase 1