cardia Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description The opening of the esophagus into the stomach; also: the part of the stomach adjoining this opening. (BRENDA Tissue and Enzyme Source Ontology, BTO_0000198)
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Genes

192 proteins co-occuring with the tissue cardia in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 1.71688
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 1.70495
PLCE1 phospholipase C, epsilon 1 1.37179
SPNS2 spinster homolog 2 (Drosophila) 1.21001
PSCA prostate stem cell antigen 1.206
TP53 tumor protein p53 1.1829
KRT7 keratin 7, type II 1.1829
MUC5B mucin 5B, oligomeric mucus/gel-forming 1.15939
AAAS achalasia, adrenocortical insufficiency, alacrimia 1.1266
CKAP5 cytoskeleton associated protein 5 1.12305
KRT20 keratin 20, type I 1.11376
MUC6 mucin 6, oligomeric mucus/gel-forming 1.1111
CRP C-reactive protein, pentraxin-related 1.07
GAST gastrin 1.03566
GATA5 GATA binding protein 5 1.00632
IL1RN interleukin 1 receptor antagonist 0.983254
MUC2 mucin 2, oligomeric mucus/gel-forming 0.946947
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit 0.904127
INS insulin 0.900296
FLRT1 fibronectin leucine rich transmembrane protein 1 0.887557
HSPB7 heat shock 27kDa protein family, member 7 (cardiovascular) 0.85547
UBQLN3 ubiquilin 3 0.838672
ZBTB20 zinc finger and BTB domain containing 20 0.837414
TUBE1 tubulin, epsilon 1 0.82736
MIR25 microRNA 25 0.807299
ERBB2 erb-b2 receptor tyrosine kinase 2 0.779401
TNNI3 troponin I type 3 (cardiac) 0.760742
ZNF135 zinc finger protein 135 0.73062
ITLN2 intelectin 2 0.717882
NLRP9 NLR family, pyrin domain containing 9 0.710909
IL1B interleukin 1, beta 0.70845
CDX2 caudal type homeobox 2 0.705583
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae) 0.677395
SCN10A sodium channel, voltage gated, type X alpha subunit 0.673728
TRIM24 tripartite motif containing 24 0.668436
GHRL ghrelin/obestatin prepropeptide 0.651371
MIR363 microRNA 363 0.645695
PES1 pescadillo ribosomal biogenesis factor 1 0.640023
CHGA chromogranin A 0.637999
EVL Enah/Vasp-like 0.621024
MUC1 mucin 1, cell surface associated 0.620217
CST3 cystatin C 0.612555
ANXA10 annexin A10 0.600881
NLRC5 NLR family, CARD domain containing 5 0.569622
SLC35E2B solute carrier family 35, member E2B 0.566828
MYT1L myelin transcription factor 1-like 0.565631
GGT1 gamma-glutamyltransferase 1 0.55607
CTSW cathepsin W 0.554876
BRWD1 bromodomain and WD repeat domain containing 1 0.549709
POMC proopiomelanocortin 0.547724
GATA4 GATA binding protein 4 0.54217
MYT1 myelin transcription factor 1 0.538209
FAM132A family with sequence similarity 132, member A 0.53346
MNX1 motor neuron and pancreas homeobox 1 0.531089
MUSTN1 musculoskeletal, embryonic nuclear protein 1 0.529903
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.527139
ALB albumin 0.512564
NCK2 NCK adaptor protein 2 0.509027
APOB apolipoprotein B 0.507457
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 0.505887
COL4A6 collagen, type IV, alpha 6 0.504318
IFITM2 interferon induced transmembrane protein 2 0.488667
SHBG sex hormone-binding globulin 0.486716
APOA1 apolipoprotein A-I 0.486326
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2 0.482817
CHD3 chromodomain helicase DNA binding protein 3 0.481259
IL10 interleukin 10 0.478145
CARD8 caspase recruitment domain family, member 8 0.478145
IL17F interleukin 17F 0.476589
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.472315
NLRX1 NLR family member X1 0.468048
DGAT2L6 diacylglycerol O-acyltransferase 2-like 6 0.468048
CPA2 carboxypeptidase A2 (pancreatic) 0.463013
AURKAIP1 aurora kinase A interacting protein 1 0.461078
S1PR2 sphingosine-1-phosphate receptor 2 0.457214
KLK15 kallikrein-related peptidase 15 0.449501
NPPA natriuretic peptide A 0.437589
ST5 suppression of tumorigenicity 5 0.434523
LPAR1 lysophosphatidic acid receptor 1 0.43414
PYCR1 pyrroline-5-carboxylate reductase 1 0.431843
PDLIM1 PDZ and LIM domain 1 0.428018
SCNN1D sodium channel, non voltage gated 1 delta subunit 0.427636
F7 coagulation factor VII (serum prothrombin conversion accelerator) 0.426109
SST somatostatin 0.413532
SH3GL1 SH3-domain GRB2-like 1 0.410491
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 0.401007
ZNF217 zinc finger protein 217 0.397222
CDKN2A cyclin-dependent kinase inhibitor 2A 0.392686
SUB1 SUB1 homolog (S. cerevisiae) 0.392309
MBTPS1 membrane-bound transcription factor peptidase, site 1 0.390421
MIR93 microRNA 93 0.376494
MGEA5 meningioma expressed antigen 5 (hyaluronidase) 0.374618
INSIG2 insulin induced gene 2 0.373868
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 0.373493
PGC progastricsin (pepsinogen C) 0.373118
SOX17 SRY (sex determining region Y)-box 17 0.37087
ERCC2 excision repair cross-complementation group 2 0.368624
CXCL8 chemokine (C-X-C motif) ligand 8 0.364513
HFE hemochromatosis 0.363766
RPGRIP1L RPGRIP1-like 0.361901
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 0.360782
MECOM MDS1 and EVI1 complex locus 0.358174
CTSZ cathepsin Z 0.355942
ENO2 enolase 2 (gamma, neuronal) 0.355198
TFF2 trefoil factor 2 0.354455
TET1 tet methylcytosine dioxygenase 1 0.352969
MKNK1 MAP kinase interacting serine/threonine kinase 1 0.352969
TLR4 toll-like receptor 4 0.352598
ERAS ES cell expressed Ras 0.351856
KLF10 Kruppel-like factor 10 0.347038
CNTN3 contactin 3 (plasmacytoma associated) 0.344449
NPY2R neuropeptide Y receptor Y2 0.344449
TFF1 trefoil factor 1 0.34371
IGLV3-9 immunoglobulin lambda variable 3-9 (gene/pseudogene) 0.338177
GKN2 gastrokine 2 0.336336
EPHX2 epoxide hydrolase 2, cytoplasmic 0.335233
CDH17 cadherin 17, LI cadherin (liver-intestine) 0.33413
MTTP microsomal triglyceride transfer protein 0.328994
UBAP1 ubiquitin associated protein 1 0.328262
ATAD3A ATPase family, AAA domain containing 3A 0.327164
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1 0.324605
GSTM1 glutathione S-transferase mu 1 0.324239
SLC23A1 solute carrier family 23 (ascorbic acid transporter), member 1 0.323874
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein 0.319863
MESP1 mesoderm posterior basic helix-loop-helix transcription factor 1 0.318407
THEM4 thioesterase superfamily member 4 0.314409
CLMP CXADR-like membrane protein 0.314046
MET MET proto-oncogene, receptor tyrosine kinase 0.311145
OGT O-linked N-acetylglucosamine (GlcNAc) transferase 0.309335
EMP2 epithelial membrane protein 2 0.304279
IGFBP3 insulin-like growth factor binding protein 3 0.303919
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1 0.30032
FABP2 fatty acid binding protein 2, intestinal 0.29996
PPT1 palmitoyl-protein thioesterase 1 0.29996
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.298524
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) 0.297447
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 0.295655
CCK cholecystokinin 0.291365
TFF3 trefoil factor 3 (intestinal) 0.286026
SCGB2A2 secretoglobin, family 2A, member 2 0.285316
NOTCH1 notch 1 0.284962
FNDC3A fibronectin type III domain containing 3A 0.284607
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3 0.282837
MUC4 mucin 4, cell surface associated 0.281423
NLRC4 NLR family, CARD domain containing 4 0.279659
TCF21 transcription factor 21 0.278955
PER2 period circadian clock 2 0.278603
TBX18 T-box 18 0.2779
TNNT2 troponin T type 2 (cardiac) 0.276495
OR2AG1 olfactory receptor, family 2, subfamily AG, member 1 (gene/pseudogene) 0.274045
HAND1 heart and neural crest derivatives expressed 1 0.274045
FUT2 fucosyltransferase 2 (secretor status included) 0.274045
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.273346
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.269867
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 0.267791
BCL2L11 BCL2-like 11 (apoptosis facilitator) 0.267791
DEFA5 defensin, alpha 5, Paneth cell-specific 0.266069
KRT81 keratin 81, type II 0.265381
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 0.265038
KRAS Kirsten rat sarcoma viral oncogene homolog 0.264353
PHF20 PHD finger protein 20 0.263327
SI sucrase-isomaltase (alpha-glucosidase) 0.258917
DOCK1 dedicator of cytokinesis 1 0.257907
TNF tumor necrosis factor 0.256902
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 0.254902
A2M alpha-2-macroglobulin 0.252261
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 0.249653
AFP alpha-fetoprotein 0.242672
FANCL Fanconi anemia, complementation group L 0.241746
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 0.236332
GRB7 growth factor receptor-bound protein 7 0.234302
GSTTP1 glutathione S-transferase theta pseudogene 1 0.233446
MIB1 mindbomb E3 ubiquitin protein ligase 1 0.233446
GSTT1 glutathione S-transferase theta 1 0.232881
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 0.230931
COL4A5 collagen, type IV, alpha 5 0.230656
MLH1 mutL homolog 1 0.230656
SOAT1 sterol O-acyltransferase 1 0.230382
OR10T2 olfactory receptor, family 10, subfamily T, member 2 0.23011
ZFPM2 zinc finger protein, FOG family member 2 0.229032
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) 0.229032
PSG9 pregnancy specific beta-1-glycoprotein 9 0.226667
CNOT8 CCR4-NOT transcription complex, subunit 8 0.225144
CDC6 cell division cycle 6 0.22246
YAP1 Yes-associated protein 1 0.220831
PLG plasminogen 0.220831
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1 0.220378
NLRP12 NLR family, pyrin domain containing 12 0.219485
DSG2 desmoglein 2 0.21883
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 0.217974
NDRG2 NDRG family member 2 0.216325
MUC7 mucin 7, secreted 0.213833