cardiac conduction system development Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description The process whose specific outcome is the progression of the cardiac conduction system over time, from its formation to the mature structure. The cardiac conduction system consists of specialized cardiomyocytes that regulate the frequency of heart beat. (Gene Ontology, GO_0003161)
External Link http://amigo.geneontology.org/amigo/term/GO:0003161
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Genes

26 genes participating in the cardiac conduction system development biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
BMP4 bone morphogenetic protein 4
BMPR1A bone morphogenetic protein receptor, type IA
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
GATA4 GATA binding protein 4
GATA6 GATA binding protein 6
GJA1 gap junction protein, alpha 1, 43kDa
GJA5 gap junction protein, alpha 5, 40kDa
GJB6 gap junction protein, beta 6, 30kDa
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
MAML1 mastermind-like 1 (Drosophila)
MSX1 msh homeobox 1
MSX2 msh homeobox 2
NKX2-5 NK2 homeobox 5
NOTCH2 notch 2
NPPA natriuretic peptide A
NPPB natriuretic peptide B
SCN5A sodium channel, voltage gated, type V alpha subunit
SHOX2 short stature homeobox 2
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SMAD1 SMAD family member 1
SMAD4 SMAD family member 4
SMAD5 SMAD family member 5
TBX18 T-box 18
TBX5 T-box 5