cardiac epithelial to mesenchymal transition Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description A transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. (Gene Ontology, GO_0060317)
External Link http://amigo.geneontology.org/amigo/term/GO:0060317
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Genes

20 genes participating in the cardiac epithelial to mesenchymal transition biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ACVRL1 activin A receptor type II-like 1
BMP2 bone morphogenetic protein 2
BMP4 bone morphogenetic protein 4
ENG endoglin
FGF8 fibroblast growth factor 8 (androgen-induced)
HAS2 hyaluronan synthase 2
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HEYL hes-related family bHLH transcription factor with YRPW motif-like
NOTCH1 notch 1
OLFM1 olfactomedin 1
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
RBPJ recombination signal binding protein for immunoglobulin kappa J region
SNAI1 snail family zinc finger 1
SNAI2 snail family zinc finger 2
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
TBX3 T-box 3
TGFB2 transforming growth factor, beta 2
TGFBR1 transforming growth factor, beta receptor 1
TGFBR3 transforming growth factor, beta receptor III